(1H-IMIDAZOL-2-YL)-METHANOL

Product Name: (1H-IMIDAZOL-2-YL)-METHANOL
CAS No.: 3724-26-3
Chemical Name: (1H-IMIDAZOL-2-YL)-METHANOL
Synonyms: 1H-IMIDAZOLE-2-METHANOL;RARECHEM AL BD 0666;Imidazole-2-methanol;2-(Hydroxymethyl)imidazol;2-HYDROXYMETHYL IMIDAZOLE;(1H-IMIDAZOL-2-YL)-METHANOL;(1H-imidazole-2-yl)-methanol;2-(Hydroxymethyl)-1H-imidazole;2-(Hydroxymethyl)-1H-imidazole 95%
CBNumber: CB5122549
Molecular Formula: C4H6N2O
Formula Weight: 98.1
MOL File: 3724-26-3.mol

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(1H-IMIDAZOL-2-YL)-METHANOL Property

Melting point:: >160℃ (dec.) (methanol water )
Boiling point:: 388.1±25.0 °C(Predicted)
Density: 1.311±0.06 g/cm3 (20 ºC 760 Torr)
storage temp.: 2-8°C
pka: 13.30±0.10(Predicted)
Appearance: White to yellow Solid
InChI: InChI=1S/C4H6N2O/c7-3-4-5-1-2-6-4/h1-2,7H,3H2,(H,5,6)
InChIKey: ZOMATQMEHRJKLO-UHFFFAOYSA-N
SMILES: C1(CO)NC=CN=1
CAS DataBase Reference: 3724-26-3(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 37/38-41
Safety Statements: 26-39
HS Code: 2933299090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

AK Scientific

Product number: J97447
Product name: 1H-Imidazol-2-ylmethanol
Packaging: 1g
Price: $217
Updated: 2021/12/16

AK Scientific

Product number: X5265
Product name: 1H-Imidazol-2-ylmethanol
Packaging: 1g
Price: $279
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H01-1-0W
Product name: 2-(Hydroxymethyl)-1H-imidazole
Purity: 95%
Packaging: 1g
Price: $424
Updated: 2021/12/16

Matrix Scientific

Product number: 084234
Product name: 1H-Imidazol-2-ylmethanol
Purity: 95%
Packaging: 1g
Price: $433
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0021052
Product name: 2-HYDROXY METHYL IMIDAZOLE
Purity: 95.00%
Packaging: 1G
Price: $808.89
Updated: 2021/12/16

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(1H-IMIDAZOL-2-YL)-METHANOL Chemical Properties,Usage,Production

Synthesis

10111-08-7

3724-26-3

General procedure for the synthesis of (1H-imidazol-2-yl)-methanol from 1H-imidazole-2-carboxaldehyde: A solution of 1H-imidazole-2-carboxaldehyde (5 g, 52.08 mmol) in methanol (50 mL) was added to a 500 mL round-bottomed flask, and the ice bath was cooled to 0 °C. Sodium borohydride (3.93 g, 104.16 mmol) was added in batches with stirring, removed from the ice bath after addition, and the reaction mixture was allowed to stir at room temperature for 3 hours. Upon completion of the reaction, the reaction was quenched with saturated sodium chloride solution (25 mL) and subsequently concentrated under reduced pressure in a rotary evaporator to remove most of the solvent. The crude product was purified by silica gel column chromatography with 10% methanol/chloroform (v/v) as eluent to afford (1H-imidazol-2-yl)-methanol as a light yellow solid (4 g, 78% yield). Thin layer chromatography (TLC) showed an Rf value of 0.1 (unfolding agent: 10% methanol/chloroform).1H NMR (400 MHz, CD3OD) δ: 6.97 (s, 2H), 4.61 (s, 2H).

References

[1] Bioorganic and Medicinal Chemistry Letters, 2013, vol. 23, # 3, p. 827 - 833
[2] Patent: WO2015/36759, 2015, A1. Location in patent: Page/Page column 200
[3] Journal of Organic Chemistry, 2010, vol. 75, # 10, p. 3208 - 3213
[4] Bioorganic and Medicinal Chemistry Letters, 2011, vol. 21, # 19, p. 5849 - 5853
[5] Patent: US9138427, 2015, B2. Location in patent: Page/Page column 302

(1H-IMIDAZOL-2-YL)-METHANOL Preparation Products And Raw materials

Raw materials

Imidazole-2-carboxaldehyde Sodium borohydride Methanol

Preparation Products

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(1H-IMIDAZOL-2-YL)-METHANOL Suppliers

Belgium 1 China 84 France 1 Germany 2 India 3 South Korea 1 The Netherlands 1 Ukraine 1 United Kingdom 3 United States 20 Global 117

Shanghai Shenghua Pharmaceutical Technology Co., LTD. (Custom Synthesis Laboratory)

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View Lastest Price from (1H-IMIDAZOL-2-YL)-METHANOL manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 1H-Imidazol-2-ylmethanol 3724-26-3
Price: US $22.00-88.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20kg
Release date: 2025-06-25

Shaanxi Dideu Medichem Co. Ltd

Product: (1H-IMIDAZOL-2-YL)-METHANOL 3724-26-3
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20T
Release date: 2024-07-12

Career Henan Chemical Co

Product: 1H-Imidazol-2-ylmethanol 3724-26-3
Price: US $1.00/KG
Min. Order: 1KG
Purity: Min98%HPLC
Supply Ability: g/kg/ton
Release date: 2020-02-01

3724-26-3, (1H-IMIDAZOL-2-YL)-METHANOLRelated Search:

1H-Imidazol-2-carboxamide imidazole-4-carboxamide IMIDAZO[1,2-A]PYRIDINE-6-CARBOXYLIC ACID Imidazole Imidazo[1,5-a]pyridine Methyl 4-imidazolecarboxylate 1H-Imidazole-2-carboxylic acid Imidazo[1,2-a]pyridine-8-carboxaldehyde (9CI) Imidazo[1,2-a]pyrazin-3-ylamine Imidazo[1,2-a]pyridine-7-carboxylic acid (9CI) Imidazo[1,2-a]pyridine-6-carbaldehyde IMidazo[1,2-a]pyridine-3-aceticacid,ethylester Imidazo[1,2-a]pyridine IMidazo[1,2-a]pyridine-7-... IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID 2-(1,7-diazabicyclo[4.3.0]nona-2,4,6,8-tetraen-8-yl)acetic acid IMIDAZO[1,2-A]PYRAZINE-2-CARBALDEHYDE 1H-IMIDAZOLE-2-CARBOXYLIC ACID METHYL ESTER

2-(Hydroxymethyl)-1H-imidazole

2-(Hydroxymethyl)-1H-imidazole 95%

(1H-IMIDAZOL-2-YL)-METHANOL

1H-IMIDAZOLE-2-METHANOL

2-HYDROXYMETHYL IMIDAZOLE

RARECHEM AL BD 0666

Imidazole-2-methanol

2-(Hydroxymethyl)imidazol

(1H-imidazole-2-yl)-methanol

3724-26-3

3725-26-3

Hydroxymethyl's

Imidazoles & Benzimidazoles

pharmacetical