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(1H-IMIDAZOL-2-YL)-METHANOL

Product Name
(1H-IMIDAZOL-2-YL)-METHANOL
CAS No.
3724-26-3
Chemical Name
(1H-IMIDAZOL-2-YL)-METHANOL
Synonyms
1H-IMIDAZOLE-2-METHANOL;RARECHEM AL BD 0666;Imidazole-2-methanol;2-(Hydroxymethyl)imidazol;2-HYDROXYMETHYL IMIDAZOLE;(1H-IMIDAZOL-2-YL)-METHANOL;(1H-imidazole-2-yl)-methanol;2-(Hydroxymethyl)-1H-imidazole;2-(Hydroxymethyl)-1H-imidazole 95%
CBNumber
CB5122549
Molecular Formula
C4H6N2O
Formula Weight
98.1
MOL File
3724-26-3.mol
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(1H-IMIDAZOL-2-YL)-METHANOL Property

Melting point:
>160℃ (dec.) (methanol water )
Boiling point:
388.1±25.0 °C(Predicted)
Density 
1.311±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. 
2-8°C
pka
13.30±0.10(Predicted)
Appearance
White to yellow Solid
InChI
InChI=1S/C4H6N2O/c7-3-4-5-1-2-6-4/h1-2,7H,3H2,(H,5,6)
InChIKey
ZOMATQMEHRJKLO-UHFFFAOYSA-N
SMILES
C1(CO)NC=CN=1
CAS DataBase Reference
3724-26-3(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
37/38-41
Safety Statements 
26-39
HS Code 
2933299090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

AK Scientific
Product number
J97447
Product name
1H-Imidazol-2-ylmethanol
Packaging
1g
Price
$217
Updated
2021/12/16
AK Scientific
Product number
X5265
Product name
1H-Imidazol-2-ylmethanol
Packaging
1g
Price
$279
Updated
2021/12/16
SynQuest Laboratories
Product number
4H01-1-0W
Product name
2-(Hydroxymethyl)-1H-imidazole
Purity
95%
Packaging
1g
Price
$424
Updated
2021/12/16
Matrix Scientific
Product number
084234
Product name
1H-Imidazol-2-ylmethanol
Purity
95%
Packaging
1g
Price
$433
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0021052
Product name
2-HYDROXY METHYL IMIDAZOLE
Purity
95.00%
Packaging
1G
Price
$808.89
Updated
2021/12/16
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(1H-IMIDAZOL-2-YL)-METHANOL Chemical Properties,Usage,Production

Synthesis

10111-08-7

3724-26-3

General procedure for the synthesis of (1H-imidazol-2-yl)-methanol from 1H-imidazole-2-carboxaldehyde: A solution of 1H-imidazole-2-carboxaldehyde (5 g, 52.08 mmol) in methanol (50 mL) was added to a 500 mL round-bottomed flask, and the ice bath was cooled to 0 °C. Sodium borohydride (3.93 g, 104.16 mmol) was added in batches with stirring, removed from the ice bath after addition, and the reaction mixture was allowed to stir at room temperature for 3 hours. Upon completion of the reaction, the reaction was quenched with saturated sodium chloride solution (25 mL) and subsequently concentrated under reduced pressure in a rotary evaporator to remove most of the solvent. The crude product was purified by silica gel column chromatography with 10% methanol/chloroform (v/v) as eluent to afford (1H-imidazol-2-yl)-methanol as a light yellow solid (4 g, 78% yield). Thin layer chromatography (TLC) showed an Rf value of 0.1 (unfolding agent: 10% methanol/chloroform).1H NMR (400 MHz, CD3OD) δ: 6.97 (s, 2H), 4.61 (s, 2H).

References

[1] Bioorganic and Medicinal Chemistry Letters, 2013, vol. 23, # 3, p. 827 - 833
[2] Patent: WO2015/36759, 2015, A1. Location in patent: Page/Page column 200
[3] Journal of Organic Chemistry, 2010, vol. 75, # 10, p. 3208 - 3213
[4] Bioorganic and Medicinal Chemistry Letters, 2011, vol. 21, # 19, p. 5849 - 5853
[5] Patent: US9138427, 2015, B2. Location in patent: Page/Page column 302

(1H-IMIDAZOL-2-YL)-METHANOL Preparation Products And Raw materials

Raw materials

Imidazole-2-carboxaldehyde Sodium borohydride Methanol

Preparation Products

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(1H-IMIDAZOL-2-YL)-METHANOL Suppliers

Belgium 1 China 84 France 1 Germany 2 India 3 South Korea 1 The Netherlands 1 Ukraine 1 United Kingdom 3 United States 20 Global 117
Service Chemical Inc.
Tel
--
Fax
--
Email
sales@chemos-group.com
Country
Germany
ProdList
6350
Advantage
71
Rare Chemicals GmbH
Tel
--
Fax
--
Email
sales@rarechem.de
Country
Germany
ProdList
6297
Advantage
38
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View Lastest Price from (1H-IMIDAZOL-2-YL)-METHANOL manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
1H-Imidazol-2-ylmethanol 3724-26-3
Price
US $22.00-88.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20kg
Release date
2025-06-25
Shaanxi Dideu Medichem Co. Ltd
Product
(1H-IMIDAZOL-2-YL)-METHANOL 3724-26-3
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2024-07-12
Career Henan Chemical Co
Product
1H-Imidazol-2-ylmethanol 3724-26-3
Price
US $1.00/KG
Min. Order
1KG
Purity
Min98%HPLC
Supply Ability
g/kg/ton
Release date
2020-02-01

3724-26-3, (1H-IMIDAZOL-2-YL)-METHANOLRelated Search:

1H-Imidazol-2-carboxamide imidazole-4-carboxamide IMIDAZO[1,2-A]PYRIDINE-6-CARBOXYLIC ACID Imidazole Imidazo[1,5-a]pyridine Methyl 4-imidazolecarboxylate 1H-Imidazole-2-carboxylic acid Imidazo[1,2-a]pyridine-8-carboxaldehyde (9CI) Imidazo[1,2-a]pyrazin-3-ylamine Imidazo[1,2-a]pyridine-7-carboxylic acid (9CI) Imidazo[1,2-a]pyridine-6-carbaldehyde IMidazo[1,2-a]pyridine-3-aceticacid,ethylester Imidazo[1,2-a]pyridine IMidazo[1,2-a]pyridine-7-... IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID 2-(1,7-diazabicyclo[4.3.0]nona-2,4,6,8-tetraen-8-yl)acetic acid IMIDAZO[1,2-A]PYRAZINE-2-CARBALDEHYDE 1H-IMIDAZOLE-2-CARBOXYLIC ACID METHYL ESTER

  • 2-(Hydroxymethyl)-1H-imidazole
  • 2-(Hydroxymethyl)-1H-imidazole 95%
  • (1H-IMIDAZOL-2-YL)-METHANOL
  • 1H-IMIDAZOLE-2-METHANOL
  • 2-HYDROXYMETHYL IMIDAZOLE
  • RARECHEM AL BD 0666
  • Imidazole-2-methanol
  • 2-(Hydroxymethyl)imidazol
  • (1H-imidazole-2-yl)-methanol
  • 3724-26-3
  • 3725-26-3
  • Hydroxymethyl's
  • Imidazoles & Benzimidazoles
  • Imidazoles & Benzimidazoles
  • pharmacetical