IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID

Product Name: IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID
CAS No.: 64951-08-2
Chemical Name: IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID
Synonyms: MFCD13188642;AKOS BBS-00006401;TIMTEC-BB SBB010195;CHEMBRDG-BB 4401038;ASINEX-REAG BAS 06100978;Minodronic Acid Impurity 25;2-Carboxyimidazo[1,2-a]pyridine;IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID;H-imidazo[1,2-a]pyridine-2-carboxylic acid;1H-Imidazo[1,2-a]pyridine-2-carboxylic acid
CBNumber: CB7290024
Molecular Formula: C8H6N2O2
Formula Weight: 162.15
MOL File: 64951-08-2.mol

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IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID Property

Melting point:: 232-234℃
Density: 1.41±0.1 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
form: Powder
pka: -4.33±0.41(Predicted)
color: White to off-white
InChI: 1S/C8H6N2O2/c11-8(12)6-5-10-4-2-1-3-7(10)9-6/h1-5H,(H,11,12)
InChIKey: WQLJLPDGSLZYEP-UHFFFAOYSA-N
SMILES: OC(=O)c1cn2ccccc2n1
CAS DataBase Reference: 64951-08-2(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38-36-22
Safety Statements: 26-36/37/39-22
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29332900
Storage Class: 11 - Combustible Solids
Hazard Classifications: Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 737569
Product name: Imidazo[1,2-a]pyridine-2-carboxylic acid
Purity: technical grade, 85%
Packaging: 500mg
Price: $50.1
Updated: 2023/06/20

TRC

Product number: I387563
Product name: Imidazo[1,2-a]pyridine-2-carboxylic acid
Packaging: 100mg
Price: $45
Updated: 2021/12/16

Matrix Scientific

Product number: 020265
Product name: Imidazo[1,2-a]pyridine-2-carboxylic acid
Packaging: 1g
Price: $44
Updated: 2021/12/16

Apolloscientific

Product number: OR9880
Product name: Imidazo[1,2-a]pyridine-2-carboxylic acid
Packaging: 100mg
Price: $10
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H21-1-16
Product name: Imidazo[1,2-a]pyridine-2-carboxylic acid
Purity: 98%
Packaging: 100mg
Price: $20
Updated: 2021/12/16

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IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID Chemical Properties,Usage,Production

Chemical Properties

White to off-white solid

Synthesis

38922-77-9

64951-08-2

Step 2: Synthesis of imidazo[1,2-a]pyridine-2-carboxylic acid Sodium hydroxide (85 mg, 2.1 mmol) was added to a stirred solution of ethyl imidazo[1,2-a]pyridine-2-carboxylate (135 mg, 0.7 mmol) in ethanol/water (1:1, 5.0 mL). The reaction mixture was heated at 60°C for 3 hours. After completion of the reaction, the mixture was concentrated under reduced pressure. Cold water was added, followed by acidification with 10% aqueous hydrochloric acid to pH < 7. The precipitated solid was collected by filtration and dried to afford imidazo[1,2-a]pyridine-2-carboxylic acid (110 mg, 73% yield).

References

[1] Patent: US2010/160323, 2010, A1. Location in patent: Page/Page column 31
[2] Journal of Medicinal Chemistry, 2003, vol. 46, # 18, p. 3914 - 3929
[3] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 5, p. 1870 - 1873
[4] Bioorganic and Medicinal Chemistry Letters, 2017, vol. 27, # 7, p. 1572 - 1575

IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

N-Bromosuccinimide Ethyl bromopyruvate Ethyl pyruvate Carbon tetrachloride Tetrahydrofuran 2-Aminopyridine

Preparation Products

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IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID Suppliers

Belgium 1 Canada 1 China 151 France 1 Germany 6 India 8 Russia 2 Switzerland 1 Ukraine 3 United Kingdom 5 United States 38 Global 217

J & K SCIENTIFIC LTD.

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ChemFuture PharmaTech (Jiangsu) Ltd

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Alfa Aesar

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Pure Chemistry Scientific Inc.

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View Lastest Price from IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID manufacturers

Career Henan Chemical Co

Product: IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID 64951-08-2
Price: US $1.00/g
Min. Order: 1g
Purity: 99.0%
Supply Ability: 100 kg
Release date: 2020-01-10

Nanjing jinheyou Trading Co., Ltd.

Product: IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID 64951-08-2
Price: US $0.00/g
Min. Order: 1g
Purity: 95%min
Supply Ability: 20kg/month
Release date: 2019-12-23

64951-08-2, IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACIDRelated Search:

IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER IMIDAZO[1,2-A]PYRIDIN-3-CARBOXALDEHYDE IMIDAZO[1,2-A]PYRIDIN-2-YLMETHANOL IMIDAZO[1,2-A]PYRIDINE-8-CARBOXYLIC ACID Imidazo[1,2-a]pyridine-7-carboxylic acid (9CI),H-imidazo[1,2-a]pyridine-7-carboxylic acid H-imidazo[1,2-a]pyridine-6-carboxylic acid H-imidazo[1,2-a]pyridine-3-carboxylic acid Imidazo[1,2-a]pyridin-5-ylamine IMIDAZO[1,2-A]PYRAZINE-3-CARBALDEHYDE IMIDAZO[1,2-A]PYRIDIN-6-OL ETHYL IMIDAZO[1,2-A]PYRIDINE-7-CARBOXYLATE 98 Dimethyl 4,5-imidazoledicarboxylate Imidazo[1,2-a]pyridine-6-boronic acid Ethyl Imidazo[1,2-a]pyridine-3-carboxylate IMIDAZO[1,5-A]PYRIDINE-1-CARBOXYLIC ACID ETHYL ESTER ETHYL IMIDAZO[1,2-A]PYRAZINE-2-CARBOXYLATE METHYL IMIDAZO[1,2-A]PYRIDINE-6-CARBOXYLATE Imidazo[1,2-a]pyridine-6-boronic acic pinacol ester

TIMTEC-BB SBB010195

ASINEX-REAG BAS 06100978

CHEMBRDG-BB 4401038

IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID

AKOS BBS-00006401

imidazo[1,2-a]pyridine-2-carboxylic acid(SALTDATA: HCl H2O)

Imidazo[1,2-a]pyridine-2-carboxylic acid monohydrate, 97%

1H-Imidazo[1,2-a]pyridine-2-carboxylic acid

H-imidazo[1,2-a]pyridine-2-carboxylic acid

Imidazo[1,2-a]pyridine-2-carboxylic acid ,97%

sodium imidazo[1,2-a]pyridine-2-carboxylate 0.5 hydrate

IMidazo[1,2-a]pyridine-2-carboxylic acid hydrate, 95%

2-Carboxyimidazo[1,2-a]pyridine

IMidazo[1,2-a]pyridine-2-carboxylic acid.HBr

MFCD13188642

Minodronic Acid Impurity 25

2-amino-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine-4-carboxam...

Imidazo[1,2-<i>a</i>]pyridine-2-carboxylic acid

64951-08-2

C8H5N2O2Na

C8H6N2O2H2O

Heterocycle-Pyridine series

Building Blocks

Imidazo[x,x-y]pyridine

pharmacetical

Carboxylic Acids

Fused Ring Systems