ChemicalBook > CAS DataBase List > 1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose

1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose

Product Name
1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose
CAS No.
18968-05-3
Chemical Name
1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose
Synonyms
1,3,4,6-Tetra-O<;beta-D-Mannopyranose tetraacetate;1,3,4,6-Tetra-O-acetyl-ββ-D-Mannopyranose 1,3,4,6-tetraacetate;1,3,4,6-Tetraacetate β-D-Mannopyranose;1,3,4,6-Tetra-O-acetyl-β-D-maopyranose;1,3,4,6-Tetra-O-acetyl-?D-mannopyranose;1,3,4,6-O-Tetraacetyl-β-D-Mannopyranose;β-d-mannopyranose 1,3,4,6-tetra-o-acetate;1,3,4,6-TETRA-O-ACETYL-SS-D-MANNOPYRANOSE
CBNumber
CB1361140
Molecular Formula
C14H20O10
Formula Weight
348.3
MOL File
18968-05-3.mol
More
Less

1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose Property

Melting point:
160-161 °C(lit.)
Boiling point:
425.5±45.0 °C(Predicted)
Density 
1.33±0.1 g/cm3(Predicted)
refractive index 
-22.5 ° (C=1.4, CHCl3)
storage temp. 
Sealed in dry,2-8°C
solubility 
very faint turbidity in Chloroform
form 
powder to crystal
pka
12.22±0.70(Predicted)
color 
White to Almost white
optical activity
[α]19/D 68°, c = 0.7 in pyridine
BRN 
96634
InChI
InChI=1/C14H20O10/c1-6(15)20-5-10-12(21-7(2)16)13(22-8(3)17)11(19)14(24-10)23-9(4)18/h10-14,19H,5H2,1-4H3/t10-,11+,12-,13-,14-/s3
InChIKey
SHBHJRVMGYVXKK-XVIXHAIJSA-N
SMILES
[C@@H]1(OC(=O)C)[C@@H](COC(=O)C)O[C@@H](OC(=O)C)[C@@H](O)[C@H]1OC(=O)C |&1:0,5,12,17,19,r|
CAS DataBase Reference
18968-05-3(CAS DataBase Reference)
More
Less

Safety

Safety Statements 
22-24/25
WGK Germany 
3
HS Code 
29400090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
310247
Product name
1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose
Purity
98%
Packaging
100mg
Price
$148.16
Updated
2025/07/31
TCI Chemical
Product number
T1459
Product name
1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose
Purity
>97.0%(GC)
Packaging
1g
Price
$139
Updated
2025/07/31
TCI Chemical
Product number
T1459
Product name
1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose
Purity
>97.0%(GC)
Packaging
5g
Price
$418
Updated
2025/07/31
Usbiological
Product number
021414
Product name
1,3,4,6-Tetra-O-acetyl-&beta;-D-mannopyranose
Packaging
250mg
Price
$460
Updated
2021/12/16
TRC
Product number
T282760
Product name
1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose
Packaging
250mg
Price
$165
Updated
2021/12/16
More
Less

1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose Chemical Properties,Usage,Production

Uses

1,3,4,6-Tetra-o-acetyl-beta-d-mannopyranose is an intermediate in the preparation of precursors of 2-[18F]fluoro-2-deoxy-D-glucose for diagnostic use in positron emission tomography.

Synthesis

28140-37-6

18968-05-3

General procedure for the synthesis of (2S,3S,4R,5R,6R)-6-(acetyloxymethyl)-3-hydroxytetrahydro-2H-pyran-2,4,5-triyl triacetate from 1,2-O-(1-ethoxyethylidene)-β-D-mannopyranose triacetate: to a solution of anhydrous acetone (27 mL) of the protoacid ester (4.4 g, 12 mmol), a slow addition of a 1 M aqueous hydrochloric acid (HCl) solution (2.7 mL), and the reaction was carried out under vigorous stirring (the water bath temperature was maintained at about 18 °C). The reaction mixture was continued to be stirred at room temperature for 5 min before being concentrated on a rotary evaporator, keeping the temperature below 20 °C. The concentrated solid was dissolved in chloroform (CHCl3, 25 mL) and washed with deionized water (2 x 10 mL). The organic phase was dried over anhydrous sodium sulfate (Na2SO4) and filtered, and the filtrate was concentrated on a rotary evaporator. The residue was ground with ether (Et2O) and recrystallized from ethanol (EtOH) to give the target product tetraacetylmannose (1.9 g, 45% yield) as a white solid. Thin layer chromatography (TLC) Rf value was 0.13 (unfolding agent: hexane/ethyl acetate = 1:1). The melting point is 134-136°C. High Resolution Mass Spectrometry (HRMS-ESI): m/z C14H20NaO10 ([M+Na]+) Calculated value 371.09542, measured value 371.09581 (error 0.39 mmu, 1.06 ppm).

References

[1] Bioorganic and Medicinal Chemistry, 2018, vol. 26, # 8, p. 1848 - 1858
[2] Tetrahedron, 1992, vol. 48, # 47, p. 10249 - 10264
[3] Tetrahedron Letters, 2013, vol. 54, # 17, p. 2190 - 2193

1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose Suppliers

Canada 1 China 102 France 1 Germany 5 India 3 Japan 1 Russia 1 Switzerland 1 United Kingdom 6 United States 9 Global 130
Tel
0531-88821801 15192360884
Fax
0531-88821802
Email
605818151@qq.com
Country
China
ProdList
417
Advantage
58
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
Advantage
66
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15402
Advantage
60
Tel
025-66113011 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19913
Advantage
55
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28387
Advantage
80
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22514
Advantage
55
More
Less

View Lastest Price from 1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose 18968-05-3
Price
US $0.00/Kg/Bag
Min. Order
1KG
Purity
98%min HPLC
Supply Ability
100KGS
Release date
2021-06-24
Hebei Chuanghai Biotechnology Co., Ltd
Product
1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose 18968-05-3
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-18
Career Henan Chemical Co
Product
1,3,4,6-TETRA-O-ACETYL-BETA-D-MANNOPYRANOSE 18968-05-3
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1tons
Release date
2018-08-08

18968-05-3, 1,3,4,6-Tetra-O-acetyl-β-D-mannopyranoseRelated Search:

1,3-BUTANEDIOL DIACETATE 1,1,3-TRIETHOXYPROPANE Mannitol 1,3-Diacetoxy-2-(acetoxymethoxy)propane 1,4-DIACETOXYBUTANE Diacetin 2-[(Acetyloxy)methoxy]ethyl acetate D-Mannitol D-LYXOSE L(+)-Rhamnose monohydrate 1,6-Diacetoxyhexane 2-Butoxyethyl acetate 1,1,3-TRIMETHOXYBUTANE TATM D-Mannose (R)-1,2-4-TRIACETOXYBUTANE BETA-METHYL-D-LYXOPYRANOSIDE 1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose

  • 1,3,4,6-TETRA-O-ACETYL-BETA-D-MANNOPYRANOSE
  • 1,2,3,4-TETRA-O-ACETYL-BETA-D-MANNOPYRANOSE
  • 1,3,4,6-Tetraacetate β-D-Mannopyranose
  • 1,3,4,6-O-Tetraacetyl-β-D-Mannopyranose
  • [(2R,3R,4R,5S,6S)-3,4,6-triacetyloxy-5-hydroxyoxan-2-yl]methyl acetate
  • (2S,3S,4R,5R,6R)-6-(Acetoxymethyl)-3-hydroxytetrahydro-2H-pyran-2,4,5-triyl triacetate
  • 1,3,4,6-Tetra-<i>O</i>-acetyl-&beta
  • 1,3,4,6-Tetra-O-acetyl-?D-mannopyranose
  • 1-O,3-O,4-O,6-O-Tetraacetyl-β-D-mannopyranose
  • β-D-Mannopyranose 1,3,4,6-tetraacetate
  • beta-D-Mannopyranose tetraacetate
  • 1,3,4,6-Tetra-O-acetyl-β-D-maopyranose
  • β-d-mannopyranose 1,3,4,6-tetra-o-acetate
  • 1,3,4,6-TETRA-O-ACETYL-SS-D-MANNOPYRANOSE
  • 1,3,4,6-TETRA-O-ACETYL-BETA-D-MANNOPYRANOSE 98+%
  • 1,2,3,4-TETRA-O-ACETYL-SS-D-MANNOPYRANOSE
  • β-D-Mannopyranose, 1, 3, 4, 6-tetraacetate18968-05-3
  • Β-D-MANNOPYRANOSE, 1, 3, 4, 6-TETRAACETATE
  • 1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose
  • 1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose USP/EP/BP
  • 1,3,4,6-Tetra-<i>O<
  • 1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose, CAS 18968-05-3
  • 1,3,4,6-Tetra-O-acetyl-β-D-pyridinylmannose
  • 18968-05-3
  • C14H20O10
  • O-Substituted Sugars
  • Sugars
  • Carbohydrate Synthesis
  • Specialty Synthesis
  • Monosaccharides
  • Intermediates & Fine Chemicals
  • Labeling and Diagnostics Reagents
  • Pharmaceuticals
  • Carbohydrates & Derivatives
  • Biochemistry
  • O-Substituted Sugars
  • Sugars
  • chiral
  • Glycon Biochem