ChemicalBook > CAS DataBase List > ε-Caprolactone

ε-Caprolactone

Product Name
ε-Caprolactone
CAS No.
502-44-3
Chemical Name
ε-Caprolactone
Synonyms
CAPROLACTONE;2-OXEPANONE;oxepan-2-one;EPSILON-CAPROLACTONE;E-CAPROLACTONE;Oxepanone;6-HEXANOLACTONE;Polycaprolactone Polyol;6-CAPROLACTONE;6-Hydroxyhexan-6-olide
CBNumber
CB1362738
Molecular Formula
C6H10O2
Formula Weight
114.14
MOL File
502-44-3.mol
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ε-Caprolactone Property

Melting point:
-1 °C
Boiling point:
96-97.5 °C10 mm Hg(lit.)
Density 
1.03 g/mL at 25 °C(lit.)
vapor density 
3.9 (vs air)
vapor pressure 
0.01 mm Hg ( 20 °C)
refractive index 
n20/D 1.463(lit.)
Flash point:
229 °F
storage temp. 
Store below +30°C.
solubility 
Chloroform, Ethyl Acetate
form 
Liquid
color 
Clear colorless, yellowing on aging
explosive limit
1.2-9%(V)
Water Solubility 
>1000 MG/L (20 ºC)
BRN 
106919
InChIKey
PAPBSGBWRJIAAV-UHFFFAOYSA-N
LogP
0.32 at 20℃
CAS DataBase Reference
502-44-3(CAS DataBase Reference)
NIST Chemistry Reference
2-Oxepanone(502-44-3)
EPA Substance Registry System
2-Oxepanone (502-44-3)
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Safety

Hazard Codes 
Xi
Risk Statements 
37/38-41-36/38
Safety Statements 
26-39-37/39
WGK Germany 
2
RTECS 
MO8400000
Autoignition Temperature
204 °C
TSCA 
Yes
HS Code 
29322090
Hazardous Substances Data
502-44-3(Hazardous Substances Data)
Toxicity
LD50 orally in Rabbit: > 2000 mg/kg LD50 dermal Rabbit 5990 mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
704067
Product name
ω-Caprolactone
Purity
97%
Packaging
100g
Price
$41.99
Updated
2025/07/31
Sigma-Aldrich
Product number
8.02801
Product name
ε-Caprolactone
Purity
for synthesis
Packaging
250ML
Price
$61.9
Updated
2025/07/31
Sigma-Aldrich
Product number
704067
Product name
ω-Caprolactone
Purity
97%
Packaging
500g
Price
$146
Updated
2025/07/31
TCI Chemical
Product number
C0702
Product name
epsilon-Caprolactone
Purity
>99.0%(GC)
Packaging
25mL
Price
$17
Updated
2025/07/31
TCI Chemical
Product number
C0702
Product name
epsilon-Caprolactone
Purity
>99.0%(GC)
Packaging
500mL
Price
$41
Updated
2025/07/31
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ε-Caprolactone Chemical Properties,Usage,Production

Chemical Properties

Clear colorless liquid, yellowing on ageing

Uses

Intermediate in adhesives, urethane coatings, and elastomers; solvent; diluent for epoxy resins; synthetic fibers; organic synthesis.

Uses

ε-Caprolactone is widely used as a monomer in the manufacturing of highly specialized polymers. It is mainly utilized as a precursor to caprolactam. It finds an application in the synthesis of polyglecaprone, which is used as a suture material in surgery.

Uses

ε-caprolactone is popularly used in the preparation of poly caprolactone (PCL).

Definition

ChEBI: A epsilon-lactone that is oxepane substituted by an oxo group at position 2.

Synthesis Reference(s)

Journal of the American Chemical Society, 80, p. 4079, 1958 DOI: 10.1021/ja01548a063
The Journal of Organic Chemistry, 61, p. 4560, 1996 DOI: 10.1021/jo952237x
Tetrahedron Letters, 17, p. 2455, 1976 DOI: 10.1016/0040-4039(76)90018-6

General Description

ε-caprolactone is a cyclic ester. Ring opening polymerization of ε-caprolactone initiated by, tributylin n butoxide, ethyl magnesium bromide, or samarium acetate or heteropolyacid, leads to the formation of poly caprolactone (PCL).

Flammability and Explosibility

Not classified

ε-Caprolactone Preparation Products And Raw materials

Raw materials

Peroxyacetic acid Ozone Cyclohexanone

Preparation Products

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View Lastest Price from ε-Caprolactone manufacturers

Weifang Integratechem Co., Ltd.
Product
ε-Caprolactone，Epsilon-Caprolactone monomer 502-44-3
Price
US $0.00/kg
Min. Order
1600kg
Purity
99%
Supply Ability
35 ton per month
Release date
2025-08-22
Hebei Chuanghai Biotechnology Co., Ltd
Product
6-Hexanolactone 502-44-3
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-10-25
Hebei Zhuanglai Chemical Trading Co Ltd
Product
6-Hexanolactone 502-44-3
Price
US $79.00-38.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-12-02

502-44-3, ε-CaprolactoneRelated Search:

Spironolactone Dodecyl acrylate Styrene D-(+)-Glucono-1,5-lactone γ-Valerolactone Gibberellin A4 PICROTOXIN DL-CAMPHORIC ANHYDRIDE PICROTOXININ Polycaprolactone (1R,3S)-(-)-CAMPHORIC ANHYDRIDE Nomilin 22(S),23(S)-HOMOBRASSINOLIDE Brassinolide POLYCAPROLACTONE-BLOCK-POLYTETRAHYDROFURAN-BLOCK-POLYCAPROLACTONE 1,2,3,4-Cyclobutanetetracarboxylic Dianhydride 7-BUTYL-2-OXEPANONE heteratisine

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  • 6-Caprolactone monomer
  • 6-Hexanalactone
  • 6-Hexanolacetone
  • 6-Hydroxyhexan-6-olide
  • 6-Hydroxyhexanoic acid lactone
  • 6-hydroxyhexanoicacidlactone
  • 6-hydroxy-hexanoicaciepsilon-lactone
  • 6-hydroxy-hexanoicacilactone
  • caprolactonemonomer
  • epsilon-Kaprolakton
  • Polycaprolactone Polyol
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  • epsilon-Hexalactone epsilon-Hexanolactone
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  • E-CAPROLACTONE FOR SYNTHESIS
  • epsilon-Caprolactone 97%
  • 1,6-Hexanolide
  • 1-Oxa-2-oxocycloheptane
  • 2-Oxacycloheptanone
  • Hexanoic acid, epsilon-lactone
  • hexanoicacid,epsilon-lactone
  • oxepan-2-one
  • Placcel M
  • placcelm
  • epsilon-Caprolactone MonoMer, 99% 1KG
  • epsilon-Caprolactone MonoMer, 99% 250GR
  • epsilon-kaprolakton(czech)
  • Hexamethylene oxide, 2-oxo-
  • Hexan-6-olide
  • Hexanoic acid, 6-hydroxy-, epsilon-lactone
  • Hexanoic acid, 6-hydroxy-, lactone
  • &epsi:-Caprolactone monomer
  • hexano-6-lactone
  • ε-Caprolactone 〔6-Hexanolide〕
  • ε-CaproL
  • 2-OXEPANONE
  • 6-Hexanolactone~2-Oxepanone
  • 6-CAPROLACTONE
  • 6-HEXANOLACTONE
  • 6-HEXANOLIDE
  • 6-HYDROXYCAPROIC ACID LACTONE
  • CAPROLACTONE
  • E-CAPROLACTONE
  • EPSILON-CAPROLACTONE
  • EPSILON-HEXALACTONE
  • EPSILON-HEXANOLACTONE
  • EPSILON-CAPROLACTONE MONOMER
  • gama-Caprolactone
  • gama-Hexalactone
  • EPSILON-CAPROLACTONE, 99+%
  • E-CAPROLACTONE MONOMER
  • epsilon-Caprolactone monomer, 99+%
  • EPSILON-HEXANOICLACTONE
  • 1-isocyanato-4-[(4-isocyanatocyclohexyl)methyl]cyclohexane
  • 2-Oxepanone, 6-Caprolactone monomer, 6-Hexanolactone
  • Oxepanone