7-Chloro-1-tetralone

Uses

Product Name: 7-Chloro-1-tetralone
CAS No.: 26673-32-5
Chemical Name: 7-Chloro-1-tetralone
Synonyms: 7-chloro-3,4-dihydronaphthalen-1(2H)-one;7-chloro-3;7-CHLORO-1-TETRALONE;7-Chloro-α-Tetralone;7-Chloro-1-tetralone >7-Chloro-3,4-dihydro-2H-phthalen-1-one;7-CHLORO-3,4-DIHYDRO-2H-NAPHTHALEN-1-ONE;1(2H)-Naphthalenone, 7-chloro-3,4-dihydro-;7-chloro-1,2,3,4-tetrahydronaphthalen-1-one;4-benzoyl-3H-benzo[f]quinoline-3-carbonitrile
CBNumber: CB1364868
Molecular Formula: C10H9ClO
Formula Weight: 180.63
MOL File: 26673-32-5.mol

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7-Chloro-1-tetralone Property

Melting point:: 93.0 to 97.0 °C
Boiling point:: 115°C/0.3mmHg(lit.)
Density: 1.248±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: soluble in Toluene
form: powder to crystal
color: White to Yellow to Green
λmax: 305nm(MeOH)(lit.)
InChI: InChI=1S/C10H9ClO/c11-8-5-4-7-2-1-3-10(12)9(7)6-8/h4-6H,1-3H2
InChIKey: IIMAYXKDBHTQHC-UHFFFAOYSA-N
SMILES: C1(=O)C2=C(C=CC(Cl)=C2)CCC1
CAS DataBase Reference: 26673-32-5

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Safety

Hazard Codes: Xn
Risk Statements: 22
HS Code: 2914790090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical

Product number: C2976
Product name: 7-Chloro-1-tetralone
Purity: >95.0%(GC)
Packaging: 1g
Price: $40
Updated: 2025/07/31

TCI Chemical

Product number: C2976
Product name: 7-Chloro-1-tetralone
Purity: >95.0%(GC)
Packaging: 5g
Price: $203
Updated: 2025/07/31

TRC

Product number: C429313
Product name: 7-Chloro-1-tetralone
Packaging: 100mg
Price: $60
Updated: 2021/12/16

TRC

Product number: C429313
Product name: 7-Chloro-1-tetralone
Packaging: 500mg
Price: $90
Updated: 2021/12/16

AK Scientific

Product number: W4993
Product name: 7-Chloro-1-tetralone
Packaging: 1g
Price: $54
Updated: 2021/12/16

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7-Chloro-1-tetralone Chemical Properties,Usage,Production

Uses

7-Chloro-1-tetralone (cas# 26673-32-5) is a useful research chemical.

Chemical Properties

Pale yellow to white crystalline powder

Synthesis

4619-18-5

26673-32-5

General procedure for the synthesis of 7-chloro-3,4-dihydro-2H-1-naphthalenone from 4-(4-chlorophenyl)butyric acid: polyphosphoric acid (20 g, excess) was placed in a beaker and heated to 90 °C. 4-(4-Chlorophenyl)butyric acid (3 g, 17 mmol) was added in batches. The reaction mixture was stirred for 5 minutes and then polyphosphoric acid (20 g, excess) was added and continued to be heated at 90°C for 5 minutes. The resulting thick orange viscous oil was cooled to 60 °C, followed by the slow addition of water. After completion of the reaction, the mixture was cooled to room temperature and extracted with ethyl acetate (EtOAc). The organic phase was washed sequentially with water, 1N NaOH solution and water, dried with anhydrous magnesium sulfate (MgSO4) and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography to give a white solid product (2.5 g, 81% yield). The product was characterized by 1H NMR (400 MHz, CDCl3): δ 2.12-2.18 (m, 2H), 2.67 (t, J = 6.8 Hz, 2H), 2.95 (t, J = 6.8 Hz, 2H), 7.22 (d, J = 8.0 Hz, 1H), 7.42 (dd, J = 10.2, 2.4 Hz, 1H), 7.85 (d , J = 2.4 Hz, 1H).

References

[1] Angewandte Chemie - International Edition, 2017, vol. 56, # 41, p. 12476 - 12480
[2] Angew. Chem., 2017, vol. 129, p. 12650 - 12654,5
[3] Journal of Medicinal Chemistry, 2009, vol. 52, # 21, p. 6768 - 6781
[4] Patent: WO2017/150904, 2017, A1. Location in patent: Paragraph 312-314
[5] Synthetic Communications, 1991, vol. 21, # 8-9, p. 981 - 987

7-Chloro-1-tetralone Preparation Products And Raw materials

Raw materials

Preparation Products

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7-Chloro-1-tetralone Suppliers

Americas 1 China 126 Europe 1 Germany 1 India 9 Japan 1 United Kingdom 2 United States 18 Global 159

TOKYO CHEMICAL INDUSTRY CO., LTD.

Tel: 03-36680489
Fax: 03-3668-0520
Email: Sales-JP@TCIchemicals.com
Country: Japan
ProdList: 28387
Advantage: 80

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View Lastest Price from 7-Chloro-1-tetralone manufacturers

Shanghai UCHEM Inc.

Product: 7-Chloro-1-tetralone 26673-32-5
Price: US $17.00-152.00/g
Min. Order: 10g
Purity: 0.98
Supply Ability: 25kg
Release date: 2024-10-25

Shanghai Rlavie Technology Co ltd

Product: 7-Chloro-1-tetralone 26673-32-5
Price: US $0.00-0.00/KG
Min. Order: 1g
Purity: 98%minHPLC
Supply Ability: 100kgs/month
Release date: 2021-11-15

Honest Joy Holdings Limited

Product: 7-chloro-3,4-dihydro-2H-naphthalen-1-one 26673-32-5
Price: US $0.00/KG
Min. Order: 1KG
Purity: 97.5%
Supply Ability: 100 tons
Release date: 2022-01-14

26673-32-5, 7-Chloro-1-tetraloneRelated Search:

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7-chloro-3,4-dihydronaphthalen-1(2H)-one

7-chloro-3

7-chloro-1,2,3,4-tetrahydronaphthalen-1-one

1(2H)-Naphthalenone, 7-chloro-3,4-dihydro-

7-CHLORO-1-TETRALONE

7-CHLORO-3,4-DIHYDRO-2H-NAPHTHALEN-1-ONE

7-Chloro-α-Tetralone

7-Chloro-3,4-dihydro-2H-phthalen-1-one

4-benzoyl-3H-benzo[f]quinoline-3-carbonitrile

7-Chloro-1-tetralone &gt

7-Chloro-3,4-dihydronaphthalen-1(2<i>H</i>)-one

26673-32-5

C10H9CIO