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4-Amino-3-methylphenol

Product Name
4-Amino-3-methylphenol
CAS No.
2835-99-6
Chemical Name
4-Amino-3-methylphenol
Synonyms
4-AMINO-3-METHYLPHENOL;4-AMINO-3-CRESOL;Phenol, 4-amino-3-methyl-;p-Hydroxy-o-toluidine;3-Methyl-4-aminophenol;JAROCOL 4A3MP;4-amino-meta-;Amino-M-Cresol;4-amino-cresol;4-amino-m-creso
CBNumber
CB1365623
Molecular Formula
C7H9NO
Formula Weight
123.15
MOL File
2835-99-6.mol
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4-Amino-3-methylphenol Property

Melting point:
176-179 °C (lit.)
Boiling point:
229.26°C (rough estimate)
Density 
1.0877 (rough estimate)
refractive index 
1.5380 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
soluble in Methanol
pka
10.34±0.18(Predicted)
form 
Powder
color 
Brown
Water Solubility 
insoluble
BRN 
2078803
InChIKey
QGNGOGOOPUYKMC-UHFFFAOYSA-N
LogP
0.51 at 22℃
CAS DataBase Reference
2835-99-6(CAS DataBase Reference)
NIST Chemistry Reference
4-Amino-3-methyl phenol(2835-99-6)
EPA Substance Registry System
Phenol, 4-amino-3-methyl- (2835-99-6)
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37/38-20/21/22
Safety Statements 
26-37/39-36/37/39-36-24/25
RIDADR 
UN3077
WGK Germany 
3
RTECS 
GO6826000
F 
8-10-23
TSCA 
Yes
HazardClass 
9
PackingGroup 
III
HS Code 
29222900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H400Very toxic to aquatic life

Precautionary statements

P273Avoid release to the environment.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
144894
Product name
4-Amino-3-methylphenol
Purity
97%
Packaging
5g
Price
$44.4
Updated
2024/03/01
Sigma-Aldrich
Product number
144894
Product name
4-Amino-3-methylphenol
Purity
97%
Packaging
25g
Price
$155
Updated
2024/03/01
TCI Chemical
Product number
A0288
Product name
4-Amino-m-cresol
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$58
Updated
2024/03/01
Alfa Aesar
Product number
B23152
Product name
4-Amino-3-methylphenol, 98%
Packaging
100g
Price
$157.65
Updated
2024/03/01
TRC
Product number
A898190
Product name
4-Amino-3-methylphenol
Packaging
50g
Price
$75
Updated
2021/12/16
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4-Amino-3-methylphenol Chemical Properties,Usage,Production

Description

4-Amino-3-methylphenol is a metabolite of 3-methyl-4-nitrophenol. It is a major metabolite of carcinogenic o-toluidine and causes DNA damage in the presence of Cu(II).

Chemical Properties

Light gray powder

Uses

4-Amino-3-methylphenol is a useful reagent for the synthesis of piperidine (piperazine)-amide substituted derivatives as multi-target antipsychotics.
4-Amino-3-methylphenol was used in synthesis of a new type of tweezer-molecule in which a strongly preferred binding conformation is generated by convergent, intramolecular hydrogen bonding.

Application

4-Amino-m-cresol is used as an oxidative hair dye at a maximum concentration of 1.5% after mixing with peroxide.

Definition

ChEBI: 4-hydroxy-6-methylaniline is a substituted aniline in which the aniline ring carries 4-hydroxy and 6-methyl substituents; a urinary metabolite of lidocaine. It has a role as a drug metabolite. It is a member of phenols and a substituted aniline.

General Description

4-Amino-3-methylphenol is a metabolite of 3-methyl-4-nitrophenol. It is a major metabolite of carcinogenic o-toluidine and causes DNA damage in the presence of Cu(II).

Flammability and Explosibility

Not classified

Synthesis

The synthesis of 4-Amino-3-methylphenol is as follows:A mixture of the para-benzoquinone mono-oxime (1.26 mmol),SnCl2 (0.72 g, 3.80 mmol), 20 mL of CH2Cl2, and 0.2 mL of concentrated HCl, was heated to reflux for 16 h. The CH2Cl2 was removed under reduced pressure, and the residue was dissolved in ethyl acetate and washed with concentrated aqueous NaHCO3. The organic layer was dried over anhydrous Na2SO4 and the filtrate was concentrated under reduced pressure to afford the solid product.

Purification Methods

Crystallise it from 50% EtOH. [Beilstein 13 H 593, 13 IV 1698.]

4-Amino-3-methylphenol Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Amino-3-methylphenol Suppliers

Americas 1 Belgium 2 Canada 1 China 313 Europe 3 Germany 10 India 21 Italy 2 Japan 6 Slovakia 1 South Korea 1 Switzerland 2 United Kingdom 15 United States 43 Global 421
Hubei Shishun Biotechnology Co. Ltd
Tel
027-59223025 15107168801
Fax
027-59223025
Email
1718480011@qq.com
Country
China
ProdList
9855
Advantage
58
Shandong Qianyuan Polymer Material Co. , Ltd.
Tel
18678041314 18765609661
Email
2547772582@qq.com
Country
China
ProdList
881
Advantage
58
Wuxi KaiLi Biotech Co.,Ltd
Tel
0510-80721533 13327925606
Email
sales@klbiotech.com
Country
China
ProdList
129
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
Country
China
ProdList
1995
Advantage
65
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
Advantage
61
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12390
Advantage
60
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View Lastest Price from 4-Amino-3-methylphenol manufacturers

HebeiShuoshengImportandExportco.,Ltd
Product
4-Amino-m-cresol 2835-99-6
Price
US $6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000KG/Month
Release date
2024-08-09
Hebei Longbang Technology Co., Ltd
Product
4-Amino-m-cresol 2835-99-6
Price
US $6.00/kg
Min. Order
1kg
Purity
More than 99%
Supply Ability
2000KG/Month
Release date
2024-04-26
Hebei Weibang Biotechnology Co., Ltd
Product
4-Amino-m-cresol 2835-99-6
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-27

2835-99-6, 4-Amino-3-methylphenol Related Search:

m-Cresol Acetaminophen Cresol 3-Aminophenol Betaine 3-Ethylphenol Glycine o-Cresol Xylenol CHLOROPHOSPHONAZO III 2-Aminophenol ALTRENOGEST p-Cresol Tris(hydroxymethyl)aminomethane 4-Aminophenol 2-AMINO-4-CRESOL,2-AMINO-PARA-CRESOL, 97%,O-AMINO-P-CRESOL,2-AMINO-P-CRESOL 6-NITROPIPERONAL 3-Methyl-4-nitrophenol

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