ChemicalBook > CAS DataBase List > 4-Amino-3-methylphenol

4-Amino-3-methylphenol

Product Name
4-Amino-3-methylphenol
CAS No.
2835-99-6
Chemical Name
4-Amino-3-methylphenol
Synonyms
4-AMINO-3-METHYLPHENOL;4-AMINO-3-CRESOL;Phenol, 4-amino-3-methyl-;p-Hydroxy-o-toluidine;3-Methyl-4-aminophenol;JAROCOL 4A3MP;4-amino-meta-;Amino-M-Cresol;4-amino-cresol;4-amino-m-creso
CBNumber
CB1365623
Molecular Formula
C7H9NO
Formula Weight
123.15
MOL File
2835-99-6.mol
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4-Amino-3-methylphenol Property

Melting point:
176-179 °C (lit.)
Boiling point:
229.26°C (rough estimate)
Density 
1.0877 (rough estimate)
refractive index 
1.5380 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
soluble in Methanol
pka
10.34±0.18(Predicted)
form 
Powder
color 
Brown
Water Solubility 
insoluble
BRN 
2078803
InChIKey
QGNGOGOOPUYKMC-UHFFFAOYSA-N
LogP
0.51 at 22℃
CAS DataBase Reference
2835-99-6(CAS DataBase Reference)
NIST Chemistry Reference
4-Amino-3-methyl phenol(2835-99-6)
EPA Substance Registry System
Phenol, 4-amino-3-methyl- (2835-99-6)
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37/38-20/21/22
Safety Statements 
26-37/39-36/37/39-36-24/25
RIDADR 
UN3077
WGK Germany 
3
RTECS 
GO6826000
F 
8-10-23
TSCA 
Yes
HazardClass 
9
PackingGroup 
III
HS Code 
29222900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H400Very toxic to aquatic life

Precautionary statements

P273Avoid release to the environment.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
144894
Product name
4-Amino-3-methylphenol
Purity
97%
Packaging
5g
Price
$44.4
Updated
2024/03/01
Sigma-Aldrich
Product number
144894
Product name
4-Amino-3-methylphenol
Purity
97%
Packaging
25g
Price
$155
Updated
2024/03/01
TCI Chemical
Product number
A0288
Product name
4-Amino-m-cresol
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$58
Updated
2024/03/01
Alfa Aesar
Product number
B23152
Product name
4-Amino-3-methylphenol, 98%
Packaging
100g
Price
$157.65
Updated
2024/03/01
TRC
Product number
A898190
Product name
4-Amino-3-methylphenol
Packaging
50g
Price
$75
Updated
2021/12/16
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4-Amino-3-methylphenol Chemical Properties,Usage,Production

Description

4-Amino-3-methylphenol is a metabolite of 3-methyl-4-nitrophenol. It is a major metabolite of carcinogenic o-toluidine and causes DNA damage in the presence of Cu(II).

Chemical Properties

Light gray powder

Uses

4-Amino-3-methylphenol is a useful reagent for the synthesis of piperidine (piperazine)-amide substituted derivatives as multi-target antipsychotics.
4-Amino-3-methylphenol was used in synthesis of a new type of tweezer-molecule in which a strongly preferred binding conformation is generated by convergent, intramolecular hydrogen bonding.

Application

4-Amino-m-cresol is used as an oxidative hair dye at a maximum concentration of 1.5% after mixing with peroxide.

Definition

ChEBI: 4-hydroxy-6-methylaniline is a substituted aniline in which the aniline ring carries 4-hydroxy and 6-methyl substituents; a urinary metabolite of lidocaine. It has a role as a drug metabolite. It is a member of phenols and a substituted aniline.

General Description

4-Amino-3-methylphenol is a metabolite of 3-methyl-4-nitrophenol. It is a major metabolite of carcinogenic o-toluidine and causes DNA damage in the presence of Cu(II).

Flammability and Explosibility

Not classified

Synthesis

The synthesis of 4-Amino-3-methylphenol is as follows:A mixture of the para-benzoquinone mono-oxime (1.26 mmol),SnCl2 (0.72 g, 3.80 mmol), 20 mL of CH2Cl2, and 0.2 mL of concentrated HCl, was heated to reflux for 16 h. The CH2Cl2 was removed under reduced pressure, and the residue was dissolved in ethyl acetate and washed with concentrated aqueous NaHCO3. The organic layer was dried over anhydrous Na2SO4 and the filtrate was concentrated under reduced pressure to afford the solid product.

Purification Methods

Crystallise it from 50% EtOH. [Beilstein 13 H 593, 13 IV 1698.]

4-Amino-3-methylphenol Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Amino-3-methylphenol Suppliers

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View Lastest Price from 4-Amino-3-methylphenol manufacturers

HebeiShuoshengImportandExportco.,Ltd
Product
4-Amino-m-cresol 2835-99-6
Price
US $6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000KG/Month
Release date
2024-08-09
Hebei Longbang Technology Co., Ltd
Product
4-Amino-m-cresol 2835-99-6
Price
US $6.00/kg
Min. Order
1kg
Purity
More than 99%
Supply Ability
2000KG/Month
Release date
2024-04-26
Hebei Weibang Biotechnology Co., Ltd
Product
4-Amino-m-cresol 2835-99-6
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-27

2835-99-6, 4-Amino-3-methylphenol Related Search:

m-Cresol Acetaminophen Cresol 3-Aminophenol Betaine 3-Ethylphenol Glycine o-Cresol Xylenol CHLOROPHOSPHONAZO III 2-Aminophenol ALTRENOGEST p-Cresol Tris(hydroxymethyl)aminomethane 4-Aminophenol 2-AMINO-4-CRESOL,2-AMINO-PARA-CRESOL, 97%,O-AMINO-P-CRESOL,2-AMINO-P-CRESOL 6-NITROPIPERONAL 3-Methyl-4-nitrophenol

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