ChemicalBook > CAS DataBase List > 4-Amino-3-methylphenol

4-Amino-3-methylphenol

Product Name
4-Amino-3-methylphenol
CAS No.
2835-99-6
Chemical Name
4-Amino-3-methylphenol
Synonyms
4-AMINO-3-METHYLPHENOL;4-AMINO-3-CRESOL;Phenol, 4-amino-3-methyl-;p-Hydroxy-o-toluidine;3-Methyl-4-aminophenol;JAROCOL 4A3MP;4-amino-meta-;Amino-M-Cresol;4-amino-cresol;4-amino-m-creso
CBNumber
CB1365623
Molecular Formula
C7H9NO
Formula Weight
123.15
MOL File
2835-99-6.mol
More
Less

4-Amino-3-methylphenol Property

Melting point:
176-179 °C (lit.)
Boiling point:
229.26°C (rough estimate)
Density 
1.0877 (rough estimate)
refractive index 
1.5380 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
soluble in Methanol
pka
10.34±0.18(Predicted)
form 
Powder
color 
Brown
Water Solubility 
insoluble
BRN 
2078803
InChIKey
QGNGOGOOPUYKMC-UHFFFAOYSA-N
LogP
0.51 at 22℃
CAS DataBase Reference
2835-99-6(CAS DataBase Reference)
NIST Chemistry Reference
4-Amino-3-methyl phenol(2835-99-6)
EPA Substance Registry System
Phenol, 4-amino-3-methyl- (2835-99-6)
More
Less

Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37/38-20/21/22
Safety Statements 
26-37/39-36/37/39-36-24/25
RIDADR 
UN3077
WGK Germany 
3
RTECS 
GO6826000
F 
8-10-23
TSCA 
Yes
HazardClass 
9
PackingGroup 
III
HS Code 
29222900
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H400Very toxic to aquatic life

Precautionary statements

P273Avoid release to the environment.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
144894
Product name
4-Amino-3-methylphenol
Purity
97%
Packaging
5g
Price
$44.4
Updated
2024/03/01
Sigma-Aldrich
Product number
144894
Product name
4-Amino-3-methylphenol
Purity
97%
Packaging
25g
Price
$155
Updated
2024/03/01
TCI Chemical
Product number
A0288
Product name
4-Amino-m-cresol
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$58
Updated
2024/03/01
Alfa Aesar
Product number
B23152
Product name
4-Amino-3-methylphenol, 98%
Packaging
100g
Price
$157.65
Updated
2024/03/01
TRC
Product number
A898190
Product name
4-Amino-3-methylphenol
Packaging
50g
Price
$75
Updated
2021/12/16
More
Less

4-Amino-3-methylphenol Chemical Properties,Usage,Production

Description

4-Amino-3-methylphenol is a metabolite of 3-methyl-4-nitrophenol. It is a major metabolite of carcinogenic o-toluidine and causes DNA damage in the presence of Cu(II).

Chemical Properties

Light gray powder

Uses

4-Amino-3-methylphenol is a useful reagent for the synthesis of piperidine (piperazine)-amide substituted derivatives as multi-target antipsychotics.
4-Amino-3-methylphenol was used in synthesis of a new type of tweezer-molecule in which a strongly preferred binding conformation is generated by convergent, intramolecular hydrogen bonding.

Application

4-Amino-m-cresol is used as an oxidative hair dye at a maximum concentration of 1.5% after mixing with peroxide.

Definition

ChEBI: A substituted aniline in which the aniline ring carries 4-hydroxy and 6-methyl substituents; a urinary metabolite of lidocaine.

General Description

4-Amino-3-methylphenol is a metabolite of 3-methyl-4-nitrophenol. It is a major metabolite of carcinogenic o-toluidine and causes DNA damage in the presence of Cu(II).

Flammability and Explosibility

Not classified

Synthesis

The synthesis of 4-Amino-3-methylphenol is as follows:A mixture of the para-benzoquinone mono-oxime (1.26 mmol),SnCl2 (0.72 g, 3.80 mmol), 20 mL of CH2Cl2, and 0.2 mL of concentrated HCl, was heated to reflux for 16 h. The CH2Cl2 was removed under reduced pressure, and the residue was dissolved in ethyl acetate and washed with concentrated aqueous NaHCO3. The organic layer was dried over anhydrous Na2SO4 and the filtrate was concentrated under reduced pressure to afford the solid product.

Purification Methods

Crystallise it from 50% EtOH. [Beilstein 13 H 593, 13 IV 1698.]

4-Amino-3-methylphenol Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

4-Amino-3-methylphenol Suppliers

Americas 1 Belgium 2 Canada 1 China 293 Europe 3 Germany 10 India 21 Italy 2 Japan 6 Slovakia 1 South Korea 1 Switzerland 2 United Kingdom 15 United States 43 Global 401
Hubei Shishun Biotechnology Co. Ltd
Tel
027-59223025 15107168801
Fax
027-59223025
Email
1718480011@qq.com
Country
China
ProdList
9994
Advantage
58
Wuxi KaiLi Biotech Co.,Ltd
Tel
0510-80721533 13327925606
Email
sales@klbiotech.com
Country
China
ProdList
127
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
Country
China
ProdList
1998
Advantage
65
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12426
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9984
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9551
Advantage
66
Winchem Industrial Co. Ltd
Tel
0574-83851061
Fax
86-574-87083209
Email
info@win-chemical.com
Country
China
ProdList
500
Advantage
55
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11660
Advantage
64
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
17988
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696;
Email
info@hanhongsci.com
Country
China
ProdList
42982
Advantage
64
XiaoGan ShenYuan ChemPharm co,ltd
Tel
0712-0712-2580635 15527768850
Email
1791901229@qq.com
Country
China
ProdList
8849
Advantage
52
Beijing Isomersyn Technology CO;LTD
Tel
010-82954736 13391601435
Email
sales@isomersyn.com
Country
China
ProdList
3296
Advantage
57
Shandong Xiya Chemical Co., Ltd
Tel
13355009207 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18739
Advantage
57
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12990
Advantage
57
BEST-REAGENT
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11726
Advantage
57
RYSS TECH LTD
Tel
400-188-0725 +86 21 34310725 13611771617
Fax
+86 21 34311076
Country
China
ProdList
2002
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14443
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9823
Advantage
79
ELION INTERNATIONAL(HONGKONG) CO., LTD
Tel
177-6725-7858 15967138206
Fax
0571-85022751
Email
sales@hzbrown.com
Country
China
ProdList
73
Advantage
62
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11714
Advantage
57
ZhengZhou HuaWen Chemical Co.Ltd
Tel
0370-2785118 15343847665
Fax
QQ：3470079902
Email
huawenchem@163.com
Country
China
ProdList
3206
Advantage
55
Shanghai Nuohey Chemical Co., Ltd.
Tel
021-52212593 13761626812
Fax
+86 (21) 51062076
Email
sales@nuohey.com
Country
China
ProdList
10690
Advantage
60
ShangHai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847 13636370518
Fax
021-55068248
Email
shyysw007@163.com
Country
China
ProdList
4941
Advantage
60
Chengdu Ai Keda Chemical Technology Co., Ltd.
Tel
4008-755-333 18080918076
Fax
028-86757656
Email
800078821@qq.com
Country
China
ProdList
9725
Advantage
55
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9872
Advantage
52
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17779
Advantage
75
Beijing innoChem Science & Technology Co.,Ltd.
Tel
400-810-7969 010-59572699
Fax
010-59572688
Email
ningzi.li@inno-chem.com.cn
Country
China
ProdList
6139
Advantage
55
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9442
Advantage
58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66099280 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19918
Advantage
55
Shanghai Jian Chao Chemical Technology Co., Ltd.
Tel
021-50430803 18017383231
Fax
qq：2817624287
Email
983544897@qq.com
Country
China
ProdList
9352
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18216
Advantage
56
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 18521732826;
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25015
Advantage
65
Shanghai Raise Chemical Technology Co.,Ltd
Tel
+86-021-50935922
Fax
+86-021-33847795
Country
China
ProdList
7876
Advantage
55
Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.
Tel
+86-28-85122536 85324413
Fax
+86-28-85326443
Email
market@astatech.cn
Country
China
ProdList
8033
Advantage
55
Zouping Mingxing Chemical Co.,Ltd.
Tel
86-13605431940 13605431940
Fax
0086-0543-2240079
Email
zpmxchemical@126.com
Country
China
ProdList
2002
Advantage
62
Shanghai Huikai Chemical Technology Co., Ltd.
Tel
021-61995394 18916691159
Email
chemicalsea@163.com
Country
China
ProdList
1975
Advantage
58
Quzhou Juhua Friendship Co., Ltd
Tel
0570-3066667
Fax
0570-3063388
Country
China
ProdList
3933
Advantage
58
Beijing Universal Century Technology Co., Ltd.
Tel
400-8706899
Fax
400-8706899
Email
hysj_bj.com
Country
China
ProdList
3585
Advantage
55
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9986
Advantage
55
Huainan Kedi Chemical Factory
Tel
0554-2106669
Fax
0554-2666215
Email
sales1@kedichem.com
Country
China
ProdList
4928
Advantage
55
Bide Pharmatech Ltd.
Tel
400-1647117 15221909166
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41438
Advantage
60
Chemwill Asia Co.,Ltd.
Tel
86-21-51086038
Fax
86-21-51861608
Country
China
ProdList
2931
Advantage
58
Zhengzhou HongSheng Pharmaceutical Co., Ltd.
Tel
1352-6885213 15637198702
Fax
0371-63709726
Email
xpkchem@163.com
Country
China
ProdList
3998
Advantage
58
Hunan HuaTeng Pharmaceutical Co., Ltd.,
Tel
400-8592883 15367835770
Fax
0731-82251112
Email
viola@huatengsci.com
Country
China
ProdList
5877
Advantage
58
Credit-Chem Co., Ltd.
Tel
400-821-5857 021-64326257
Fax
021-64393586 QQ;2798200800
Email
credit-chem@foxmail.com
Country
China
ProdList
5223
Advantage
58
More
Less

View Lastest Price from 4-Amino-3-methylphenol manufacturers

Hebei Saisier Technology Co., LTD
Product
4-Amino-m-cresol 2835-99-6
Price
US $6.00/KG
Min. Order
1KG
Purity
More than 99%
Supply Ability
2000KG/Month
Release date
2024-04-17
Hebei Jingbo New Material Technology Co., Ltd
Product
4-Amino-3-methylphenol 2835-99-6
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000000
Release date
2023-12-25
Weijer International Trade (Hebei) Co., Ltd
Product
4-Amino-3-methylphenol 2835-99-6
Price
US $20.00/KG
Min. Order
1KG
Purity
>99%
Supply Ability
50000kg/Month
Release date
2023-03-14

2835-99-6, 4-Amino-3-methylphenol Related Search:

m-Cresol Acetaminophen Cresol 3-Aminophenol Betaine 3-Ethylphenol Glycine o-Cresol Xylenol CHLOROPHOSPHONAZO III 2-Aminophenol ALTRENOGEST p-Cresol Tris(hydroxymethyl)aminomethane 4-Aminophenol 2-AMINO-4-CRESOL,2-AMINO-PARA-CRESOL, 97%,O-AMINO-P-CRESOL,2-AMINO-P-CRESOL 6-NITROPIPERONAL 3-Methyl-4-nitrophenol

  • 4-amino-cresol
  • 4-amino-m-creso
  • 4-amino-m-cresol,4-hydroxy-o-toluidine,4-amino-3-methylphenol
  • m-Cresol, 4-amino-
  • Phenol, 4-amino-3-methyl-
  • p-Hydroxy-o-toluidine
  • 4-Amino-3-methylphenol,98%
  • 4-amino-meta-cresol
  • 4-Amino-m-cresol;4-Amino-3-methylphenol
  • Amino-M-Cresol
  • 4-Amino-m-methylphenol
  • PARA-AMINO-META-CRESOL
  • 4-AMino-M-cresol, 99+% 50GR
  • 2-Amino-5-hydroxytoluene, 4-Amino-m-cresol, 4-Hydroxy-2-methylaniline
  • 4-Amino-meta-cresol, 99+%
  • 4-Amino-m-cresol,99+%
  • 4-Amino-3-methylphenol 4-Hydroxy-2-methylaniline
  • 4-AMINO-3-METHYLPHENOL FOR SYNTHESIS
  • 4-AMino-3-Methylphenol, 99%, 99%
  • 4-Amino-<i>m-</i>cresol
  • C4-Amino-m-cresol
  • 4-HYDROXY-2-METHYLANILINE
  • 4-HYDROXY-O-TOLUIDINE
  • 4-AMINO-M-CRESOL
  • 4-AMINO-3-METHYLPHENOL
  • 4-AMINO-3-CRESOL
  • 2-AMINO-5-HYDROXYTOLUENE
  • JAROCOL 4A3MP
  • P-AMINO-M-CRESOL
  • 2-Methyl-4-hydroxyaniline
  • 3-Methyl-4-aminophenol
  • 4-amino-3-methyl-pheno
  • 4-hydroxy-6-methylaniline
  • 4-Amino-3-methylphenol, 98.5%
  • 4-amino-meta-
  • 4-Amino-m-cresol&gt
  • 4-Amino-m-cresol(4AMC)
  • Dopexamine Impurity 13
  • 2835-99-6
  • Phenols
  • Oxygen Compounds
  • Organic Building Blocks
  • Building Blocks
  • Aromatic Phenols