4-Amino-3-methylphenol

Product Name: 4-Amino-3-methylphenol
CAS No.: 2835-99-6
Chemical Name: 4-Amino-3-methylphenol
Synonyms: 4-AMINO-3-METHYLPHENOL;4-AMINO-3-CRESOL;Phenol, 4-amino-3-methyl-;p-Hydroxy-o-toluidine;3-Methyl-4-aminophenol;JAROCOL 4A3MP;4-amino-meta-;Amino-M-Cresol;4-amino-cresol;4-amino-m-creso
CBNumber: CB1365623
Molecular Formula: C7H9NO
Formula Weight: 123.15
MOL File: 2835-99-6.mol

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4-Amino-3-methylphenol Property

Melting point:: 176-179 °C (lit.)
Boiling point:: 229.26°C (rough estimate)
Density: 1.0877 (rough estimate)
refractive index: 1.5380 (estimate)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: soluble in Methanol
pka: 10.34±0.18(Predicted)
form: Powder
color: Brown
Water Solubility: insoluble
BRN: 2078803
InChIKey: QGNGOGOOPUYKMC-UHFFFAOYSA-N
LogP: 0.51 at 22℃
CAS DataBase Reference: 2835-99-6(CAS DataBase Reference)
NIST Chemistry Reference: 4-Amino-3-methyl phenol(2835-99-6)
EPA Substance Registry System: Phenol, 4-amino-3-methyl- (2835-99-6)

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Safety

Hazard Codes: Xn
Risk Statements: 22-36/37/38-20/21/22
Safety Statements: 26-37/39-36/37/39-36-24/25
RIDADR: UN3077
WGK Germany: 3
RTECS: GO6826000
F: 8-10-23
TSCA: Yes
HazardClass: 9
PackingGroup: III
HS Code: 29222900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H400Very toxic to aquatic life

Precautionary statements

P273Avoid release to the environment.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 144894
Product name: 4-Amino-3-methylphenol
Purity: 97%
Packaging: 5g
Price: $44.4
Updated: 2024/03/01

Sigma-Aldrich

Product number: 144894
Product name: 4-Amino-3-methylphenol
Purity: 97%
Packaging: 25g
Price: $155
Updated: 2024/03/01

TCI Chemical

Product number: A0288
Product name: 4-Amino-m-cresol
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $58
Updated: 2024/03/01

Alfa Aesar

Product number: B23152
Product name: 4-Amino-3-methylphenol, 98%
Packaging: 100g
Price: $157.65
Updated: 2024/03/01

TRC

Product number: A898190
Product name: 4-Amino-3-methylphenol
Packaging: 50g
Price: $75
Updated: 2021/12/16

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4-Amino-3-methylphenol Chemical Properties,Usage,Production

Description

4-Amino-3-methylphenol is a metabolite of 3-methyl-4-nitrophenol. It is a major metabolite of carcinogenic o-toluidine and causes DNA damage in the presence of Cu(II).

Chemical Properties

Light gray powder

Uses

4-Amino-3-methylphenol is a useful reagent for the synthesis of piperidine (piperazine)-amide substituted derivatives as multi-target antipsychotics.
4-Amino-3-methylphenol was used in synthesis of a new type of tweezer-molecule in which a strongly preferred binding conformation is generated by convergent, intramolecular hydrogen bonding.

Application

4-Amino-m-cresol is used as an oxidative hair dye at a maximum concentration of 1.5% after mixing with peroxide.

Definition

ChEBI: 4-hydroxy-6-methylaniline is a substituted aniline in which the aniline ring carries 4-hydroxy and 6-methyl substituents; a urinary metabolite of lidocaine. It has a role as a drug metabolite. It is a member of phenols and a substituted aniline.

General Description

4-Amino-3-methylphenol is a metabolite of 3-methyl-4-nitrophenol. It is a major metabolite of carcinogenic o-toluidine and causes DNA damage in the presence of Cu(II).

Flammability and Explosibility

Not classified

Synthesis

The synthesis of 4-Amino-3-methylphenol is as follows:A mixture of the para-benzoquinone mono-oxime (1.26 mmol),SnCl₂ (0.72 g, 3.80 mmol), 20 mL of CH₂Cl₂, and 0.2 mL of concentrated HCl, was heated to reflux for 16 h. The CH₂Cl₂ was removed under reduced pressure, and the residue was dissolved in ethyl acetate and washed with concentrated aqueous NaHCO₃. The organic layer was dried over anhydrous Na₂SO₄ and the filtrate was concentrated under reduced pressure to afford the solid product.

Purification Methods

Crystallise it from 50% EtOH. [Beilstein 13 H 593, 13 IV 1698.]

4-Amino-3-methylphenol Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Amino-3-methylphenol Suppliers

Americas 1 Belgium 2 Canada 1 China 313 Europe 3 Germany 10 India 21 Italy 2 Japan 6 Slovakia 1 South Korea 1 Switzerland 2 United Kingdom 15 United States 43 Global 421

Hubei Shishun Biotechnology Co. Ltd

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Alfa Aesar

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TCI (Shanghai) Development Co., Ltd.

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Energy Chemical

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Beijing Ouhe Technology Co., Ltd

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View Lastest Price from 4-Amino-3-methylphenol manufacturers

HebeiShuoshengImportandExportco.,Ltd

Product: 4-Amino-m-cresol 2835-99-6
Price: US $6.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 2000KG/Month
Release date: 2024-08-09

Hebei Longbang Technology Co., Ltd

Product: 4-Amino-m-cresol 2835-99-6
Price: US $6.00/kg
Min. Order: 1kg
Purity: More than 99%
Supply Ability: 2000KG/Month
Release date: 2024-04-26

Hebei Weibang Biotechnology Co., Ltd

Product: 4-Amino-m-cresol 2835-99-6
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-27

2835-99-6, 4-Amino-3-methylphenol Related Search:

m-Cresol Acetaminophen Cresol 3-Aminophenol Betaine 3-Ethylphenol Glycine o-Cresol Xylenol CHLOROPHOSPHONAZO III 2-Aminophenol ALTRENOGEST p-Cresol Tris(hydroxymethyl)aminomethane 4-Aminophenol 2-AMINO-4-CRESOL,2-AMINO-PARA-CRESOL, 97%,O-AMINO-P-CRESOL,2-AMINO-P-CRESOL 6-NITROPIPERONAL 3-Methyl-4-nitrophenol

4-amino-cresol

4-amino-m-creso

4-amino-m-cresol,4-hydroxy-o-toluidine,4-amino-3-methylphenol

m-Cresol, 4-amino-

Phenol, 4-amino-3-methyl-

p-Hydroxy-o-toluidine

4-Amino-3-methylphenol,98%

4-amino-meta-cresol

4-Amino-m-cresol;4-Amino-3-methylphenol

Amino-M-Cresol

4-Amino-m-methylphenol

PARA-AMINO-META-CRESOL

4-AMino-M-cresol, 99+% 50GR

2-Amino-5-hydroxytoluene, 4-Amino-m-cresol, 4-Hydroxy-2-methylaniline

4-Amino-meta-cresol, 99+%

4-Amino-m-cresol,99+%

4-Amino-3-methylphenol 4-Hydroxy-2-methylaniline

4-AMINO-3-METHYLPHENOL FOR SYNTHESIS

4-AMino-3-Methylphenol, 99%, 99%

4-Amino-<i>m-</i>cresol

C4-Amino-m-cresol

4-HYDROXY-2-METHYLANILINE

4-HYDROXY-O-TOLUIDINE

4-AMINO-M-CRESOL

4-AMINO-3-METHYLPHENOL

4-AMINO-3-CRESOL

2-AMINO-5-HYDROXYTOLUENE

JAROCOL 4A3MP

P-AMINO-M-CRESOL

2-Methyl-4-hydroxyaniline

3-Methyl-4-aminophenol

4-amino-3-methyl-pheno

4-hydroxy-6-methylaniline

4-Amino-3-methylphenol, 98.5%

4-amino-meta-

4-Amino-m-cresol&gt

4-Amino-m-cresol(4AMC)

Dopexamine Impurity 13

2835-99-6

Phenols

Oxygen Compounds

Organic Building Blocks

Building Blocks

Aromatic Phenols