ChemicalBook > CAS DataBase List > 1-Methylindole

1-Methylindole

Product Name
1-Methylindole
CAS No.
603-76-9
Chemical Name
1-Methylindole
Synonyms
1-Methyl-1H-indole;N-METHYLINDOLE;1-METHYLINDOLE (N-);N-Methyindole;1-methyl-1h-indol;1H-Indole, 1-methyl-;CgHgN;NSC 212534;1-METHYLINDOL;L-Methylindole
CBNumber
CB1371608
Molecular Formula
C9H9N
Formula Weight
131.17
MOL File
603-76-9.mol
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1-Methylindole Property

Melting point:
61.2°C (estimate)
Boiling point:
133 °C26 mm Hg(lit.)
Density 
1.051 g/mL at 20 °C(lit.)
refractive index 
n20/D 1.606(lit.)
Flash point:
>230 °F
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Chloroform (Soluble), DMSO (Slightly)
form 
Liquid, May Develop Some Turbidity or Precipitate
color 
Colorless to white
Water Solubility 
insoluble
Sensitive 
Light Sensitive
BRN 
111026
Stability:
Light sensitive. Combustible. Incompatible with strong oxidizing agents.
InChIKey
BLRHMMGNCXNXJL-UHFFFAOYSA-N
LogP
2.720
CAS DataBase Reference
603-76-9(CAS DataBase Reference)
NIST Chemistry Reference
1H-Indole, 1-methyl-(603-76-9)
EPA Substance Registry System
1H-Indole, 1-methyl- (603-76-9)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
22-24/25-37/39-26
RIDADR 
UN 3334
WGK Germany 
3
F 
13
TSCA 
Yes
HS Code 
29339990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
193984
Product name
1-Methylindole
Purity
≥97%
Packaging
5g
Price
$43.79
Updated
2025/07/31
Sigma-Aldrich
Product number
193984
Product name
1-Methylindole
Purity
≥97%
Packaging
25g
Price
$89.58
Updated
2025/07/31
TCI Chemical
Product number
M0561
Product name
1-Methylindole
Purity
>96.0%(GC)
Packaging
5g
Price
$20
Updated
2025/07/31
TCI Chemical
Product number
M0561
Product name
1-Methylindole
Purity
>96.0%(GC)
Packaging
25g
Price
$55
Updated
2025/07/31
TRC
Product number
M313560
Product name
1-Methylindole
Packaging
5g
Price
$50
Updated
2021/12/16
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1-Methylindole Chemical Properties,Usage,Production

Chemical Properties

deep yellow viscous liquid with a very unpleasant smell

Uses

1-Methylindole is useful for the determination of association constant for the electron-donor-acceptor complexes with 1-(2,4,6-trinitrophenyl) propan-2-one. It acts as a reactant for the preparation of polycyclic derivatives of indoles, bisindole derivatives and pharmaceutically active 2-oxo-1-pyrrolidine analogues. It is also used as a reactant for the preparation of Positron Emission Tomography (PET) imaging agents of protein kinase C (PKC) and glycogen synthase kinase-3 (GSK-3).

Synthesis Reference(s)

Synthetic Communications, 26, p. 1349, 1996 DOI: 10.1080/00397919608003495
Tetrahedron Letters, 27, p. 377, 1986 DOI: 10.1016/S0040-4039(00)84023-X

General Description

1-Methylindole undergoes Au(III)/TPPMS-catalyzed benzylation reaction with benzhydryl and benzylic alcohols.

1-Methylindole Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 1-Methylindole manufacturers

Changzhou waston chemical technology Co.,Ltd
Product
1-Methylindole 603-76-9
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
As your request
Release date
2025-07-17
Hebei Chuanghai Biotechnology Co., Ltd
Product
1-Methylindole 603-76-9
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-07
Moxin Chemicals
Product
Ramosetron Impurity 603-76-9
Price
US $0.00-0.00/mg
Min. Order
10mg
Purity
95%+
Supply Ability
10000
Release date
2025-01-22

603-76-9, 1-MethylindoleRelated Search:

1-METHYL-2-INDOLINONE 3-(1-methyl-1H-indole-3-carbonyl)hexanedioic acid (3R)-2,3-Dihydro-3-(2-propyn-1-ylaMino)-1H-inden-1-one 1-Methyl-1H-indole-3-carboxylic acid Ramosetron hydrochloride Rasagiline Impurity 5 Mesylate 5-(1-methyl-1H-indole-3-carbonyl)-1H-benzo[d]imidazol-2(3H)-one ramosetron 4,5,6,7-Tetrahydro-1H-benzoiMidazole-5-carboxylic acid hydrochloride Rasagiline Impurity 3 3a,7a-dihydroxy-5-(1-methyl-1H-indole-3-carbonyl)-hexahydro-1H-benzo[d]imidazol-2(3H)-one Ramosetron Impurity 13 N-[4,5,6,7-Tetrahydrobenzimidazole-5-yl)carbonyl] pyrrolidine sulfate N-METHYLISATIN 2-Methylindole N-Ethylcarbazole 1-Methylindole-2-carboxylic acid 5-HYDROXY-2-METHYLINDOLE

  • 1-METHYLINDOLE (N-)
  • 1-METHYLINDOLE
  • 1-METHYLINDOL
  • 1H-Indole, 1-methyl-
  • L-Methylindole
  • 1-METHYLINDOLE, 97+%
  • N-Methyindole
  • 1-Methylindol, 98+%
  • 1-Methylindole,98+%
  • 1-methyl-1h-indol
  • 1-methyl-1H-indole analogue
  • NSC 212534
  • Ramosetron Impurity 13
  • N-METHYLINDOLE
  • 1-Methyl-1H-indole
  • Indole, 1-methyl-
  • 1-Methylindole&gt
  • 1-Methylindole (Ramosetron Impurity)
  • 2- 1-Methylindole
  • 603-76-9 1-Methylindole
  • 1-Methylindole pure, 97%
  • CgHgN
  • Vitamin B6 Impurity 97
  • 1-methylindote
  • 603-76-9
  • Building Blocks
  • Indoles
  • Simple Indoles
  • Heterocyclic Building Blocks
  • Heterocycle-Indole series
  • Simple Indoles
  • Building Blocks
  • Heterocyclic Building Blocks
  • Indoles
  • blocks
  • IndolesOxindoles
  • Indole
  • bc0001