Hexaethylene Glycol Monomethyl Ether
- Product Name
- Hexaethylene Glycol Monomethyl Ether
- CAS No.
- 23601-40-3
- Chemical Name
- Hexaethylene Glycol Monomethyl Ether
- Synonyms
- 2,5,8,11,14,17-hexaoxanonadecan-19-ol;MPEG6-OH;MPEG-6;m-PEG6-alcohol;HO-(CH2CH2O)6-Me;Methyl-PEG6-alcohol;HexaethyleneGlycolMonomethylEther>3,6,9,12,15,18-Hexaoxanonadecan-1-ol;HEXAETHYLENE GLYCOL MONOMETHYL ETHER;3,6,9,12,15,18-Hexaoxanonadecane-1-ol
- CBNumber
- CB1373804
- Molecular Formula
- C13H28O7
- Formula Weight
- 296.36
- MOL File
- 23601-40-3.mol
Hexaethylene Glycol Monomethyl Ether Property
- Boiling point:
- 167 °C / 1mmHg
- Density
- 1,08 g/cm3
- refractive index
- 1.4510-1.4550
- storage temp.
- -20°C
- form
- clear liquid
- pka
- 14.36±0.10(Predicted)
- color
- Colorless to Light yellow to Light orange
- InChI
- InChI=1S/C13H28O7/c1-15-4-5-17-8-9-19-12-13-20-11-10-18-7-6-16-3-2-14/h14H,2-13H2,1H3
- InChIKey
- FHHGCKHKTAJLOM-UHFFFAOYSA-N
- SMILES
- C(O)COCCOCCOCCOCCOCCOC
- CAS DataBase Reference
- 23601-40-3
- EPA Substance Registry System
- 2,5,8,11,14,17-Hexaoxanonadecan-19-ol (23601-40-3)
Safety
- WGK Germany
- WGK 3
- TSCA
- TSCA listed
- HS Code
- 29094990
- Storage Class
- 10 - Combustible liquids
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- H0808
- Product name
- Hexaethylene Glycol Monomethyl Ether
- Purity
- >97.0%(GC)
- Packaging
- 1g
- Price
- $111
- Updated
- 2025/07/31
- Product number
- H0808
- Product name
- Hexaethylene Glycol Monomethyl Ether
- Purity
- >97.0%(GC)
- Packaging
- 5g
- Price
- $332
- Updated
- 2025/07/31
- Product number
- H0808
- Product name
- Hexaethylene Glycol Monomethyl Ether
- Purity
- >97.0%(GC)
- Packaging
- 25g
- Price
- $996
- Updated
- 2025/07/31
- Product number
- CHM0129350
- Product name
- HEXAETHYLENE GLYCOL MONOMETHYL ETHER
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $1082.74
- Updated
- 2021/12/16
- Product number
- 281404
- Product name
- mPEG6-OH
- Purity
- >=95%
- Packaging
- 25g
- Price
- $600
- Updated
- 2021/12/16
Hexaethylene Glycol Monomethyl Ether Chemical Properties,Usage,Production
Description
m-PEG6-alcohol is a PEG linker containing a hydroxyl group. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The hydrophilic PEG spacer increases solubility in aqueous media.
Uses
Applications may include: bioconjugation, drug delivery, PEG hydrogel, crosslinker, and surface functionalization
Definition
ChEBI: Hexaethylene glycol monomethyl ether is a hydroxypolyether. It is functionally related to a hexaethylene glycol.
reaction suitability
reagent type: cross-linking reagent
Synthesis
62921-74-8
112-27-6
23601-40-3
Under stirring conditions, 2-(2-(2-methoxyethoxy)ethoxy)ethyl 4-methylbenzenesulfonate (1.0 g, 3.14 mmol) was slowly added to triethylene glycol (2.10 mL, 15.7 mmol). Subsequently, potassium hydroxide (510 mg, 9.42 mmol) was ground into a fine powder and added to the reaction system. The reaction mixture was refluxed at 100 °C for 12 hours. After completion of the reaction, the reaction mixture was diluted with deionized water (50 mL) and extracted with dichloromethane. The organic phases were combined, dried with anhydrous sodium sulfate and concentrated under reduced pressure to afford 2,5,8,11,14,17-hexaoxanonadecan-19-ol as a yellow oil in 69% yield.
IC 50
PEGs
References
[1] Journal of Organic Chemistry, 2006, vol. 71, # 20, p. 7499 - 7508
[2] Organic Letters, 2004, vol. 6, # 4, p. 469 - 472
[3] Patent: WO2015/143185, 2015, A1. Location in patent: Paragraph 00819
[4] Patent: WO2016/40891, 2016, A2. Location in patent: Paragraph 00316
[5] Bulletin of the Korean Chemical Society, 2011, vol. 32, # 7, p. 2193 - 2198
Hexaethylene Glycol Monomethyl Ether Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Hexaethylene Glycol Monomethyl Ether manufacturers
- Product
- mPEG6-OH 23601-40-3
- Price
- US $19.90-2899.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 300kg
- Release date
- 2025-12-19
- Product
- 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL 23601-40-3
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 1g/bottle, 10g/bottle, 100g/bottle
- Release date
- 2025-09-10
- Product
- m-PEG6-alcohol 23601-40-3
- Price
- US $0.00/g
- Min. Order
- 25g
- Purity
- >98.00%
- Supply Ability
- 25g
- Release date
- 2024-03-27