ChemicalBook > CAS DataBase List > Hexaethylene Glycol Monomethyl Ether

Hexaethylene Glycol Monomethyl Ether

Product Name
Hexaethylene Glycol Monomethyl Ether
CAS No.
23601-40-3
Chemical Name
Hexaethylene Glycol Monomethyl Ether
Synonyms
2,5,8,11,14,17-hexaoxanonadecan-19-ol;MPEG6-OH;MPEG-6;m-PEG6-alcohol;HO-(CH2CH2O)6-Me;Methyl-PEG6-alcohol;HexaethyleneGlycolMonomethylEther>3,6,9,12,15,18-Hexaoxanonadecan-1-ol;HEXAETHYLENE GLYCOL MONOMETHYL ETHER;3,6,9,12,15,18-Hexaoxanonadecane-1-ol
CBNumber
CB1373804
Molecular Formula
C13H28O7
Formula Weight
296.36
MOL File
23601-40-3.mol
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Hexaethylene Glycol Monomethyl Ether Property

Boiling point:
167 °C / 1mmHg
Density 
1,08 g/cm3
refractive index 
1.4510-1.4550
storage temp. 
-20°C
form 
clear liquid
pka
14.36±0.10(Predicted)
color 
Colorless to Light yellow to Light orange
InChI
InChI=1S/C13H28O7/c1-15-4-5-17-8-9-19-12-13-20-11-10-18-7-6-16-3-2-14/h14H,2-13H2,1H3
InChIKey
FHHGCKHKTAJLOM-UHFFFAOYSA-N
SMILES
C(O)COCCOCCOCCOCCOCCOC
CAS DataBase Reference
23601-40-3
EPA Substance Registry System
2,5,8,11,14,17-Hexaoxanonadecan-19-ol (23601-40-3)
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Safety

HS Code 
29094990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical
Product number
H0808
Product name
Hexaethylene Glycol Monomethyl Ether
Purity
>97.0%(GC)
Packaging
1g
Price
$111
Updated
2025/07/31
TCI Chemical
Product number
H0808
Product name
Hexaethylene Glycol Monomethyl Ether
Purity
>97.0%(GC)
Packaging
5g
Price
$332
Updated
2025/07/31
TCI Chemical
Product number
H0808
Product name
Hexaethylene Glycol Monomethyl Ether
Purity
>97.0%(GC)
Packaging
25g
Price
$996
Updated
2025/07/31
American Custom Chemicals Corporation
Product number
CHM0129350
Product name
HEXAETHYLENE GLYCOL MONOMETHYL ETHER
Purity
95.00%
Packaging
5G
Price
$1082.74
Updated
2021/12/16
chempep
Product number
281404
Product name
mPEG6-OH
Purity
>=95%
Packaging
25g
Price
$600
Updated
2021/12/16
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Hexaethylene Glycol Monomethyl Ether Chemical Properties,Usage,Production

Description

m-PEG6-alcohol is a PEG linker containing a hydroxyl group. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The hydrophilic PEG spacer increases solubility in aqueous media.

Uses

Applications may include: bioconjugation, drug delivery, PEG hydrogel, crosslinker, and surface functionalization

Definition

ChEBI: Hexaethylene glycol monomethyl ether is a hydroxypolyether. It is functionally related to a hexaethylene glycol.

reaction suitability

reagent type: cross-linking reagent

Synthesis

62921-74-8

112-27-6

23601-40-3

Under stirring conditions, 2-(2-(2-methoxyethoxy)ethoxy)ethyl 4-methylbenzenesulfonate (1.0 g, 3.14 mmol) was slowly added to triethylene glycol (2.10 mL, 15.7 mmol). Subsequently, potassium hydroxide (510 mg, 9.42 mmol) was ground into a fine powder and added to the reaction system. The reaction mixture was refluxed at 100 °C for 12 hours. After completion of the reaction, the reaction mixture was diluted with deionized water (50 mL) and extracted with dichloromethane. The organic phases were combined, dried with anhydrous sodium sulfate and concentrated under reduced pressure to afford 2,5,8,11,14,17-hexaoxanonadecan-19-ol as a yellow oil in 69% yield.

IC 50

PEGs

References

[1] Journal of Organic Chemistry, 2006, vol. 71, # 20, p. 7499 - 7508
[2] Organic Letters, 2004, vol. 6, # 4, p. 469 - 472
[3] Patent: WO2015/143185, 2015, A1. Location in patent: Paragraph 00819
[4] Patent: WO2016/40891, 2016, A2. Location in patent: Paragraph 00316
[5] Bulletin of the Korean Chemical Society, 2011, vol. 32, # 7, p. 2193 - 2198

Hexaethylene Glycol Monomethyl Ether Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Hexaethylene Glycol Monomethyl Ether manufacturers

LAURENT
Product
mPEG6-OH 23601-40-3
Price
US $998.00/g
Min. Order
1g
Purity
98%
Supply Ability
300kg
Release date
2025-11-20
XIAMEN SINOPEG BIOTECH CO., LTD.
Product
2,5,8,11,14,17-HEXAOXANONADECAN-19-OL 23601-40-3
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98%
Supply Ability
1g/bottle, 10g/bottle, 100g/bottle
Release date
2025-09-10
Xian confluore Biological Technology Co., Ltd.
Product
m-PEG6-alcohol 23601-40-3
Price
US $0.00/g
Min. Order
25g
Purity
>98.00%
Supply Ability
25g
Release date
2024-03-27

23601-40-3, Hexaethylene Glycol Monomethyl EtherRelated Search:

3,6,9,12,15,18-Hexaoxanonadecane-1-thiol m-PEG6-bromide [2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]acetic acid M-PEG6-CHO C12E8 NONAETHYLENE GLYCOL MONODODECYL ETHER Dicyclohexano-24-crown-8 (+)-(18-CROWN-6)-2,3,11,12-TETRACARBOXYLIC ACID C18E6 C10 E8 C14E6 C14E8 C16 E8 HEXAETHYLENE GLYCOL MONOHEXADECYL ETHER HEXAETHYLENE GLYCOL MONOMETHYL ETHER HEXAETHYLENE GLYCOL MONODECYL ETHER HEXAETHYLENE GLYCOL DIMETHYL ETHER HEXAETHYLENE GLYCOL MONODODECYL ETHER

  • HEXAETHYLENE GLYCOL MONOMETHYL ETHER
  • 2,5,8,11,14,17-hexaoxanonadecan-19-ol
  • 2-[2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethanol
  • 3,6,9,12,15,18-Hexaoxanonadecane-1-ol
  • MPEG6-OH
  • MPEG-6
  • m-PEG6-alcohol
  • Methyl-PEG6-alcohol
  • 3,6,9,12,15,18-Hexaoxanonadecan-1-ol
  • HexaethyleneGlycolMonomethylEther&gt
  • HEXAETHYLENE GLYCOL MONOMETHYL ETHER ISO 9001：2015 REACH
  • HO-(CH2CH2O)6-Me
  • mPEG6-OH/3,6,9,12,15,18-Hexaoxanonadecan-1-ol
  • 23601-40-3
  • C13H28O7
  • Ethylene Glycols & Monofunctional Ethylene Glycols
  • Monofunctional Ethylene Glycols
  • Ethylene Glycols & Monofunctional Ethylene Glycols
  • Monofunctional Ethylene Glycols
  • PEG-COOH
  • peg