[2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]acetic acid
- Product Name
- [2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]acetic acid
- CAS No.
- 16142-03-3
- Chemical Name
- [2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]acetic acid
- Synonyms
- mPEG5-CH2COOH;MPEG5-OCH2COOH;m-PEG6-CH4COOH;mPEG5-acetic acid;3,6,9,12,15,18-Hexaoxa-nonadecansaeure;3,6,9,12,15,18-Hexaoxanonadecanoic acid;2,5,8,11,14,17-Hexaoxanonadecan-19-oic acid;2,5,8,11,14,17-Hexaoxa-19-nonadecanoic Acid;mPEG5-CH2COOH/3,6,9,12,15,18-Hexaoxanonadecanoic acid;[2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]acetic acid
- CBNumber
- CB52747175
- Molecular Formula
- C13H26O8
- Formula Weight
- 310.34
- MOL File
- 16142-03-3.mol
[2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]acetic acid Property
- Boiling point:
- 418.6±40.0 °C(Predicted)
- Density
- 1.124±0.06 g/cm3(Predicted)
- pka
- 3.39±0.10(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- BP-23434
- Product name
- m-PEG6-CH2COOH
- Purity
- 98%
- Packaging
- 1g
- Price
- $310
- Updated
- 2021/12/16
- Product number
- AS104071
- Product name
- mPEG5-CH2COOH
- Purity
- 95+%
- Packaging
- 1g
- Price
- $471
- Updated
- 2021/12/16
- Product number
- 363605
- Product name
- mPEG5-CH2COOH
- Purity
- min.95%
- Packaging
- 250mg
- Price
- $152
- Updated
- 2021/12/16
- Product number
- B-0958
- Product name
- mPEG5-CH2COOH
- Purity
- 97%
- Packaging
- 0.5g
- Price
- $247.5
- Updated
- 2021/12/16
- Product number
- 363605
- Product name
- mPEG5-CH2COOH
- Purity
- min.95%
- Packaging
- 1g
- Price
- $275
- Updated
- 2021/12/16
[2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]acetic acid Chemical Properties,Usage,Production
Description
m-PEG6-CH2COOH is a PEG linker containing a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media.
Biological Activity
m-PEG5-CH2COOH is a non-cleavable ADC linker for the synthesis of antibody-drug conjugates (ADCs). It is also a PEG-based PROTAC linker, which can be used for PROTAC synthesis.
in vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
target
| Non-cleavable < span> | PEGs
|
[2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]acetic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from [2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]acetic acid manufacturers
- Product
- [2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]acetic acid 16142-03-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 97%-99.9%
- Supply Ability
- 100kg
- Release date
- 2019-12-21