mPEG8-Alkyne

Product Name: mPEG8-Alkyne
CAS No.: 880081-81-2
Chemical Name: mPEG8-Alkyne
Synonyms: mPEG8-Alkyne;MPEG8-PROPYNE;mPEG11-Alkyne;m-PEG8-O-alkyne;m-PEG9-Propargyl;2,5,8,11,14,17,20,23,26-Nonaoxanonacos-28-yne;mPEG8-Propyne/2,5,8,11,14,17,20,23,26-Nonaoxanonacos-28-yne;inhibit,m-PEG-8-O-alkyne,PROTAC Linkers,m PEG8 O alkyne,Inhibitor,mPEG8Oalkyne
CBNumber: CB82747176
Molecular Formula: C20H38O9
Formula Weight: 422.51
MOL File: 880081-81-2.mol

More

Less

mPEG8-Alkyne Property

Boiling point:: 468.8±40.0 °C(Predicted)
Density: 1.057±0.06 g/cm3(Predicted)
storage temp.: Store at 0-8 °C
form: Liquid
color: Colorless to light yellow

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

ChemPep

Product number: 283903
Product name: mPEG8-Propyne
Packaging: 1g
Price: $460
Updated: 2021/12/16

Activate Scientific

Product number: AS104121
Product name: mPEG8-Propyne
Purity: 95+%
Packaging: 1g
Price: $471
Updated: 2021/12/16

ChemPep

Product number: 283903
Product name: mPEG8-Propyne
Packaging: 5g
Price: $1499
Updated: 2021/12/16

purepeg

Product number: 3664908
Product name: mPEG8-CH2C≡CH
Purity: min.97%
Packaging: 250mg
Price: $145
Updated: 2021/12/16

purepeg

Product number: 3664908
Product name: mPEG8-CH2C≡CH
Purity: min.97%
Packaging: 1g
Price: $288
Updated: 2021/12/16

More

Less

mPEG8-Alkyne Chemical Properties,Usage,Production

Uses

m-PEG8-O-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. m-PEG8-O-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Biological Activity

m-PEG8-O-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

IC 50

PEGs

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

mPEG8-Alkyne Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

mPEG8-Alkyne Suppliers

China 39 United States 4 Global 43

ChemPep, Inc.

Tel: +1 (888) 615-9178 / (561) 791-8787
Fax: +1 (561) 791-8728
Email: service@chempep.com
Country: United States
ProdList: 2138
Advantage: 57

T&W GROUP

Tel: 021-61551611 13296011611
Fax: ＋86 21-50676805
Email: contact@trustwe.com
Country: China
ProdList: 9895
Advantage: 58

Nanjing Norris-Pharm Technology Co., Ltd

Tel: 18652989687
Fax: +86-25-52131256
Email: sales@norris-pharm.com
Country: China
ProdList: 8878
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Shanghai Boka-chem Tech. Inc.

Tel: 400-026-1533/(021) 6478-0600
Fax: +86 (21) 6459-2060
Email: sales@bokachem.com
Country: China
ProdList: 876
Advantage: 58

Tongling HengYou Biotechnology Co., Ltd.

Tel: 021-50426030 13856289449
Fax: 021-50426030
Email: 2630597085@qq.com
Country: China
ProdList: 1889
Advantage: 55

Amatek Scientific Co. Ltd.

Tel: 0512-56316828
Fax: 0512-56316826
Email: info@amateksci.com
Country: China
ProdList: 28785
Advantage: 58

Jiaxing Deyi Chemical Co., Ltd.

Tel: 86-0573-85866609 13325730825
Fax: 0573-85866609
Email: 945717149@qq.com
Country: China
ProdList: 8593
Advantage: 58

Hangzhou HanLai Biochemical Technology Co., Ltd.

Tel: 571-86101219 18768477782
Fax: -
Email: sales09@leobiochem.com
Country: China
ProdList: 433
Advantage: 58

Xi'an Confluore Biological Technology Co., Ltd.

Tel: +86-156-80926068 +86-15680926068
Email: 1924344760@qq.com
Country: China
ProdList: 4952
Advantage: 58

More

Less

View Lastest Price from mPEG8-Alkyne manufacturers

LAURENT

Product: mPEG8-Propargyl 880081-81-2
Price: US $951.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 300kg
Release date: 2025-11-18

Xian confluore Biological Technology Co., Ltd.

Product: Propargyl-PEG9-methane 880081-81-2
Price: US $0.00/g
Min. Order: 1g
Purity: >98.00%
Supply Ability: 1g
Release date: 2024-03-26

880081-81-2, mPEG8-AlkyneRelated Search:

m-PEG13-acid m-PEG5-bromide METHOXYPOLYETHYLENE GLYCOL 5,000 PROPIONIC ACID [2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]acetic acid mPEG3-CH2COOH MPEG6-CH2CH2COOH MPEG7-CH2CH2COOH MPEG4-CH2CH2COOH 1-{2-[2-(2-{2-[2-(2-Bromo-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-2-methoxy-ethane 3,6,9,12,15,18,21,24,27-Nonaoxaoctacosanoic acid Triethylene Glycol 2-Bromoethyl Methyl Ether Proparyl-PEG5-methane MPEG3-Propyne mPEG24-Propyne mPEG11-Propyne mPEG36-Propyne mPEG12-Propyne MPEG16-Propyne

MPEG8-PROPYNE

mPEG8-Alkyne

mPEG11-Alkyne

m-PEG8-O-alkyne

2,5,8,11,14,17,20,23,26-Nonaoxanonacos-28-yne

m-PEG9-Propargyl

inhibit,m-PEG-8-O-alkyne,PROTAC Linkers,m PEG8 O alkyne,Inhibitor,mPEG8Oalkyne

mPEG8-Propyne/2,5,8,11,14,17,20,23,26-Nonaoxanonacos-28-yne

880081-81-2