MPEG16-Propyne

Product Name: MPEG16-Propyne
CAS No.: 2169967-47-7
Chemical Name: MPEG16-Propyne
Synonyms: MPEG16-Propyne;m-PEG16-propargyl;2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50-Heptadecaoxatripentacont-52-yne;mPEG16-Propyne/2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50-Heptadecaoxatripentacont-52-yne;Propargyl PEG17 methane,PROTAC Linkers,inhibit,PropargylPEG17methane,Inhibitor,Propargyl-PEG-17-methane
CBNumber: CB52656925
Molecular Formula: C36H70O17
Formula Weight: 774.93
MOL File: 2169967-47-7.mol

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

chempep

Product number: 283906
Product name: mPEG16-Propyne
Purity: >=95%
Packaging: 250mg
Price: $387
Updated: 2021/12/16

ChemPep

Product number: 283906
Product name: mPEG16-Propyne
Packaging: 1g
Price: $795
Updated: 2021/12/16

Activate Scientific

Product number: AS104123
Product name: mPEG16-Propyne
Purity: 95+%
Packaging: 1g
Price: $875
Updated: 2021/12/16

purepeg

Product number: 3664916
Product name: mPEG16-CH2C≡CH
Purity: min.95%
Packaging: 250mg
Price: $220
Updated: 2021/12/16

Acrotein

Product number: B-1018
Product name: mPEG16-Propyne
Purity: 97%
Packaging: 0.25g
Price: $302.5
Updated: 2021/12/16

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MPEG16-Propyne Chemical Properties,Usage,Production

Uses

Propargyl-PEG17-methane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG17-methane is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Biological Activity

Propargyl-PEG17-methane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

IC 50

PEGs

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

MPEG16-Propyne Preparation Products And Raw materials

Raw materials

Preparation Products

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MPEG16-Propyne Suppliers

China 14 United States 3 Global 17

ChemPep, Inc.

Tel: +1 (888) 615-9178 / (561) 791-8787
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Country: United States
ProdList: 2138
Advantage: 57

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 42446
Advantage: 60

Amatek Scientific Co. Ltd.

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Email: info@amateksci.com
Country: China
ProdList: 28785
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TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 15801484223;
Email: psaitong@jm-bio.com
Country: China
ProdList: 29757
Advantage: 58

Affinity（Wuhan）Ltd.

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Email: sales@affinitytech.cn
Country: China
ProdList: 3000
Advantage: 58

Shanghai Yifei Biotechnology Co. , Ltd.

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Email: customer_service@efebio.com
Country: China
ProdList: 11973
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Accela ChemBio Co.,Ltd.

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Shandong fen Boyu Biotechnology Co.,LTD

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Hubei wei shi reagent group ltd., company

Tel: 027-59101766 13125137661
Email: 2853877621@qq.com
Country: China
ProdList: 7976
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2169967-47-7, MPEG16-PropyneRelated Search:

Propargyl-PEG7-t-butyl ester Propargyl-PEG7-acid Propargyl-PEG4-Tos Propargyl-PEG8-NHS ester Propargyl-PEG6-acid Propargyl-PEG8-t-butyl ester Propargyl-PEG6-t-butyl ester Proparyl-PEG5-methane MPEG3-Propyne mPEG8-Alkyne Propargyl-PEG8-alcohol Propargyl-PEG8-bromide Propargyl-PEG8-acid Propargyl-PEG9-bromide MPEGn-Alkyne 2K, 5K, 10K, 20K Propargyl-PEG6-Tos Propargyl-PEG7-acid Propargyl-PEG9-azide

MPEG16-Propyne

2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50-Heptadecaoxatripentacont-52-yne

Propargyl PEG17 methane,PROTAC Linkers,inhibit,PropargylPEG17methane,Inhibitor,Propargyl-PEG-17-methane

mPEG16-Propyne/2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50-Heptadecaoxatripentacont-52-yne

m-PEG16-propargyl

2169967-47-7