MPEG16-Propyne

Product Name: MPEG16-Propyne
CAS No.: 2169967-47-7
Chemical Name: MPEG16-Propyne
Synonyms: MPEG16-Propyne;m-PEG16-propargyl;2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50-Heptadecaoxatripentacont-52-yne;mPEG16-Propyne/2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50-Heptadecaoxatripentacont-52-yne;Propargyl PEG17 methane,PROTAC Linkers,inhibit,PropargylPEG17methane,Inhibitor,Propargyl-PEG-17-methane
CBNumber: CB52656925
Molecular Formula: C36H70O17
Formula Weight: 774.93
MOL File: 2169967-47-7.mol

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

chempep

Product number: 283906
Product name: mPEG16-Propyne
Purity: >=95%
Packaging: 250mg
Price: $387
Updated: 2021/12/16

ChemPep

Product number: 283906
Product name: mPEG16-Propyne
Packaging: 1g
Price: $795
Updated: 2021/12/16

Activate Scientific

Product number: AS104123
Product name: mPEG16-Propyne
Purity: 95+%
Packaging: 1g
Price: $875
Updated: 2021/12/16

purepeg

Product number: 3664916
Product name: mPEG16-CH2C≡CH
Purity: min.95%
Packaging: 250mg
Price: $220
Updated: 2021/12/16

Acrotein

Product number: B-1018
Product name: mPEG16-Propyne
Purity: 97%
Packaging: 0.25g
Price: $302.5
Updated: 2021/12/16

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MPEG16-Propyne Chemical Properties,Usage,Production

Uses

Propargyl-PEG17-methane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG17-methane is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Biological Activity

Propargyl-PEG17-methane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

IC 50

PEGs

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

MPEG16-Propyne Preparation Products And Raw materials

Raw materials

Preparation Products

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MPEG16-Propyne Suppliers

China 16 United States 3 Global 19

ChemPep, Inc.

Tel: +1 (888) 615-9178 / (561) 791-8787
Fax: +1 (561) 791-8728
Email: service@chempep.com
Country: United States
ProdList: 2138
Advantage: 57

Amatek Scientific Co. Ltd.

Tel: 0512-56316828
Fax: 0512-56316826
Email: info@amateksci.com
Country: China
ProdList: 28772
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32467
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 15801484223;
Email: psaitong@jm-bio.com
Country: China
ProdList: 29757
Advantage: 58

Affinity（Wuhan）Ltd.

Tel: 15841022315
Email: sales@affinitytech.cn
Country: China
ProdList: 3000
Advantage: 58

Shanghai Yifei Biotechnology Co. , Ltd.

Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Country: China
ProdList: 11972
Advantage: 58

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Email: marketing@accelachem.com
Country: China
ProdList: 9746
Advantage: 58

Shandong fen Boyu Biotechnology Co.,LTD

Tel: 13356310019 13356310019;
Email: boyu2024@163.com
Country: China
ProdList: 3992
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Hubei wei shi reagent group ltd., company

Tel: 17771898297 13125137661
Email: 2853877621@qq.com
Country: China
ProdList: 7756
Advantage: 58

TargetMol Chemicals Inc.

Tel: 15002134094
Email: marketing@targetmol.cn
Country: China
ProdList: 29431
Advantage: 58

2169967-47-7, MPEG16-PropyneRelated Search:

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MPEG16-Propyne

2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50-Heptadecaoxatripentacont-52-yne

Propargyl PEG17 methane,PROTAC Linkers,inhibit,PropargylPEG17methane,Inhibitor,Propargyl-PEG-17-methane

mPEG16-Propyne/2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50-Heptadecaoxatripentacont-52-yne

m-PEG16-propargyl

2169967-47-7