ChemicalBook > CAS DataBase List > [2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]acetic acid

[2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]acetic acid

Product Name
[2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]acetic acid
CAS No.
16142-03-3
Chemical Name
[2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]acetic acid
Synonyms
mPEG5-CH2COOH;MPEG5-OCH2COOH;m-PEG6-CH4COOH;mPEG5-acetic acid;3,6,9,12,15,18-Hexaoxa-nonadecansaeure;3,6,9,12,15,18-Hexaoxanonadecanoic acid;2,5,8,11,14,17-Hexaoxanonadecan-19-oic acid;2,5,8,11,14,17-Hexaoxa-19-nonadecanoic Acid;mPEG5-CH2COOH/3,6,9,12,15,18-Hexaoxanonadecanoic acid;[2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]acetic acid
CBNumber
CB52747175
Molecular Formula
C13H26O8
Formula Weight
310.34
MOL File
16142-03-3.mol
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[2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]acetic acid Property

Boiling point:
418.6±40.0 °C(Predicted)
Density 
1.124±0.06 g/cm3(Predicted)
pka
3.39±0.10(Predicted)
form 
Liquid
color 
Colorless to light yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-23434
Product name
m-PEG6-CH2COOH
Purity
98%
Packaging
1g
Price
$310
Updated
2021/12/16
Activate Scientific
Product number
AS104071
Product name
mPEG5-CH2COOH
Purity
95+%
Packaging
1g
Price
$471
Updated
2021/12/16
purepeg
Product number
363605
Product name
mPEG5-CH2COOH
Purity
min.95%
Packaging
250mg
Price
$152
Updated
2021/12/16
Acrotein
Product number
B-0958
Product name
mPEG5-CH2COOH
Purity
97%
Packaging
0.5g
Price
$247.5
Updated
2021/12/16
purepeg
Product number
363605
Product name
mPEG5-CH2COOH
Purity
min.95%
Packaging
1g
Price
$275
Updated
2021/12/16
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[2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]acetic acid Chemical Properties,Usage,Production

Description

m-PEG6-CH2COOH is a PEG linker containing a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media.

Biological Activity

m-PEG5-CH2COOH is a non-cleavable ADC linker for the synthesis of antibody-drug conjugates (ADCs). It is also a PEG-based PROTAC linker, which can be used for PROTAC synthesis.

in vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

target

Non-cleavable

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PEGs

[2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]acetic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from [2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]acetic acid manufacturers

Career Henan Chemical Co
Product
[2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]acetic acid 16142-03-3
Price
US $1.00/KG
Min. Order
1KG
Purity
97%-99.9%
Supply Ability
100kg
Release date
2019-12-21

16142-03-3, [2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]acetic acidRelated Search:

3,6,9,12,15,18-Hexaoxanonadecane-1-thiol HEXAETHYLENE GLYCOL MONOMETHYL ETHER mPEG8-Alkyne MPEG3-CH2CH2COOH m-PEG5-bromide METHOXYPOLYETHYLENE GLYCOL 5,000 PROPIONIC ACID m-PEG13-acid MPEG3-Propyne MPEG6-CH2CH2COOH MPEG7-CH2CH2COOH MPEG4-CH2CH2COOH 1-{2-[2-(2-{2-[2-(2-Bromo-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-2-methoxy-ethane Triethylene Glycol 2-Bromoethyl Methyl Ether Polyethylene Glycol mPEG3-CH2COOH mPEG6-CH2COOH 2,5,8,11,14-pentaoxahexadecan-16-oic acid Poly(propylene glycol)

  • MPEG5-OCH2COOH
  • [2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]acetic acid
  • 3,6,9,12,15,18-Hexaoxanonadecanoic acid
  • m-PEG6-CH4COOH
  • mPEG5-acetic acid
  • mPEG5-CH2COOH
  • 2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]acetic acid
  • 3,6,9,12,15,18-Hexaoxa-nonadecansaeure
  • 2,5,8,11,14,17-Hexaoxanonadecan-19-oic acid
  • mPEG5-CH2COOH/3,6,9,12,15,18-Hexaoxanonadecanoic acid
  • 2,5,8,11,14,17-Hexaoxa-19-nonadecanoic Acid
  • 16142-03-3
  • C13H26O8