MPEG3-CH2CH2COOH
- Product Name
- MPEG3-CH2CH2COOH
- CAS No.
- 67319-28-2
- Chemical Name
- MPEG3-CH2CH2COOH
- Synonyms
- mPEG4-COOH;m-PEG4-Acid;m-dPEG4-acid;Me-dPEG?4-acid;Methyl-PEG3-acid;MPEG3-CH2CH2COOH;COOHCH2CH2-PEG3-OME;mPEG3-propionic acid;Methyl-PEG3-CH2CH2COOH;MeO-(CH2CH2O)3-CH2CH2COOH
- CBNumber
- CB82546939
- Molecular Formula
- C10H20O6
- Formula Weight
- 236.26
- MOL File
- 67319-28-2.mol
MPEG3-CH2CH2COOH Property
- Boiling point:
- 352.3±32.0 °C(Predicted)
- Density
- 1.105±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- Soluble in Water
- pka
- 4.28±0.10(Predicted)
- form
- Liquid
- color
- Colorless to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- AS116748
- Product name
- mPEG3-CH2CH2COOH
- Purity
- 97+%
- Packaging
- 250mg
- Price
- $141
- Updated
- 2021/12/16
- Product number
- CS-0062370
- Product name
- m-PEG3-CH2CH2COOH
- Packaging
- 1g
- Price
- $187
- Updated
- 2021/12/16
- Product number
- 10234
- Product name
- m-dPEG®₄-acid
- Packaging
- 100mg
- Price
- $100
- Updated
- 2021/12/16
- Product number
- BP-20979
- Product name
- m-PEG4-acid
- Purity
- 98%
- Packaging
- 1g
- Price
- $230
- Updated
- 2021/12/16
- Product number
- 280801
- Product name
- mPEG3-CH2CH2COOH
- Purity
- >=95%
- Packaging
- 1g
- Price
- $231
- Updated
- 2021/12/16
MPEG3-CH2CH2COOH Chemical Properties,Usage,Production
Description
m-PEG4-acid is a PEG linker containing a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media.
Uses
m-PEG3-CH2CH2COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG3-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
IC 50
Non-cleavable Linker; PEGs
References
[1] Robert Lyon, et al. Pegylated drug-linkers for improved ligand-drug conjugate pharmacokinetics. WO2015057699A2.
MPEG3-CH2CH2COOH Preparation Products And Raw materials
Raw materials
Preparation Products
MPEG3-CH2CH2COOH Suppliers
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View Lastest Price from MPEG3-CH2CH2COOH manufacturers
- Product
- mPEG3-CH2CH2COOH 67319-28-2
- Price
- US $41.90/g
- Min. Order
- 10g
- Purity
- 98%
- Supply Ability
- 300kg
- Release date
- 2025-11-15
- Product
- m-PEG4-COOH 67319-28-2
- Price
- US $0.00/g
- Min. Order
- 10g
- Purity
- >98.00%
- Supply Ability
- 10g
- Release date
- 2024-03-27
- Product
- 4,7,10,13-Tetraoxatetradecanoic acid 67319-28-2
- Price
- US $8.80/KG
- Min. Order
- 1KG
- Purity
- 97%-99%
- Supply Ability
- 100kg
- Release date
- 2019-07-09