ChemicalBook > CAS DataBase List > MPEG3-CH2CH2COOH

MPEG3-CH2CH2COOH

Product Name: MPEG3-CH2CH2COOH
CAS No.: 67319-28-2
Chemical Name: MPEG3-CH2CH2COOH
Synonyms: mPEG4-COOH;m-PEG4-Acid;m-dPEG4-acid;Me-dPEG?4-acid;Methyl-PEG3-acid;MPEG3-CH2CH2COOH;COOHCH2CH2-PEG3-OME;mPEG3-propionic acid;Methyl-PEG3-CH2CH2COOH;MeO-(CH2CH2O)3-CH2CH2COOH
CBNumber: CB82546939
Molecular Formula: C10H20O6
Formula Weight: 236.26
MOL File: 67319-28-2.mol

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MPEG3-CH2CH2COOH Property

Boiling point:: 352.3±32.0 °C(Predicted)
Density: 1.105±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: Soluble in Water
pka: 4.28±0.10(Predicted)
form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Activate Scientific

Product number: AS116748
Product name: mPEG3-CH2CH2COOH
Purity: 97+%
Packaging: 250mg
Price: $141
Updated: 2021/12/16

ChemScene

Product number: CS-0062370
Product name: m-PEG3-CH2CH2COOH
Packaging: 1g
Price: $187
Updated: 2021/12/16

dPEG

Product number: 10234
Product name: m-dPEG®₄-acid
Packaging: 100mg
Price: $100
Updated: 2021/12/16

BroadPharm

Product number: BP-20979
Product name: m-PEG4-acid
Purity: 98%
Packaging: 1g
Price: $230
Updated: 2021/12/16

chempep

Product number: 280801
Product name: mPEG3-CH2CH2COOH
Purity: >=95%
Packaging: 1g
Price: $231
Updated: 2021/12/16

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MPEG3-CH2CH2COOH Chemical Properties,Usage,Production

Description

m-PEG4-acid is a PEG linker containing a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media.

Uses

m-PEG3-CH2CH2COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG3-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

IC 50

Non-cleavable Linker; PEGs

References

[1] Robert Lyon, et al. Pegylated drug-linkers for improved ligand-drug conjugate pharmacokinetics. WO2015057699A2.

MPEG3-CH2CH2COOH Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from MPEG3-CH2CH2COOH manufacturers

LAURENT

Product: mPEG3-CH2CH2COOH 67319-28-2
Price: US $41.90/g
Min. Order: 10g
Purity: 98%
Supply Ability: 300kg
Release date: 2025-11-15

Xian confluore Biological Technology Co., Ltd.

Product: m-PEG4-COOH 67319-28-2
Price: US $0.00/g
Min. Order: 10g
Purity: >98.00%
Supply Ability: 10g
Release date: 2024-03-27

Career Henan Chemical Co

Product: 4,7,10,13-Tetraoxatetradecanoic acid 67319-28-2
Price: US $8.80/KG
Min. Order: 1KG
Purity: 97%-99%
Supply Ability: 100kg
Release date: 2019-07-09

67319-28-2, MPEG3-CH2CH2COOHRelated Search:

1-{2-[2-(2-{2-[2-(2-Bromo-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-2-methoxy-ethane Triethylene Glycol 2-Bromoethyl Methyl Ether 13-Azido-2,5,8,11-tetraoxa-tridecane 22-Amino-5,8,11,14,17,20-hexaoxa-2-azadocosanoic acid 1,1-dimethylethyl ester 3,6,9,12,15-PENTAOXAHEPTADECANE-1,17-DIYL BIS-AMINE 6-Maleimidocaproic acid Z-8-aMino-3,6-dioxaoctanoic acid 15-biotinlaMino-4,7,10,13-dioxanonanoic acid N-hydroxysucciniMidyl ester HEPTAETHYLENE GLYCOL MONOMETHYL ETHER DECAETHYLENE GLYCOL MONOMETHYL ETHER Fmoc-NH-PEG3-CH2COOH NONAETHYLENE GLYCOL MONOMETHYL ETHER Methyl-PEG12-bromide 2,5,8,11,14-pentaoxahexadecan-16-oic acid 2,5,8,11,14,17,20-Heptaoxadocosan-22-amine Methyl-PEG10-azide Methyl-PEG9-bromide m-PEG6-bromide

MPEG3-CH2CH2COOH

4,7,10,13-Tetraoxatetradecanoic acid

m-PEG4-Acid

Methyl-PEG3-acid

mPEG3-propionic acid

COOHCH2CH2-PEG3-OME

mPEG4-COOH

2,5,8,11-Tetraoxa-14-tetradecanoic Acid

m-dPEG4-acid

MeO-(CH2CH2O)3-CH2CH2COOH

mPEG3-CH2CH2COOH/4,7,10,13-Tetraoxatetradecanoic acid

3-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]propanoic acid

Methyl-PEG3-CH2CH2COOH

m-dPEG??-acid (QBD-10234)

Me-dPEG?4-acid

67319-28-2

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