3-AMINO-4-PHENYLPYRIDINE
- Product Name
- 3-AMINO-4-PHENYLPYRIDINE
- CAS No.
- 146140-99-0
- Chemical Name
- 3-AMINO-4-PHENYLPYRIDINE
- Synonyms
- 4-phenylpyridin-3-aMine;4-PHENYL-3-PYRIDINAMINE;3-AMINO-4-PHENYLPYRIDINE;3-PyridinaMine, 4-phenyl-;4-PHENYL-PYRIDIN-3-YLAMINE;4-Phenylpyridin-3-aMine hydrochloride
- CBNumber
- CB1379705
- Molecular Formula
- C11H10N2
- Formula Weight
- 170.21
- MOL File
- 146140-99-0.mol
3-AMINO-4-PHENYLPYRIDINE Property
- Boiling point:
- 334.6±22.0 °C(Predicted)
- Density
- 1.133
- storage temp.
- 2-8°C(protect from light)
- pka
- 6.33±0.18(Predicted)
- Appearance
- White to off-white Solid
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- P399953
- Product name
- 4-Phenylpyridin-3-amine
- Packaging
- 50mg
- Price
- $110
- Updated
- 2021/12/16
- Product number
- CHM0010257
- Product name
- 3-AMINO-4-PHENYL PYRIDINE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $834.37
- Updated
- 2021/12/16
- Product number
- FA51245
- Product name
- 3-Amino-4-phenylpyridine
- Packaging
- 100mg
- Price
- $216
- Updated
- 2021/12/16
- Product number
- FA51245
- Product name
- 3-Amino-4-phenylpyridine
- Packaging
- 250mg
- Price
- $270
- Updated
- 2021/12/16
- Product number
- OR912999
- Product name
- 3-Amino-4-phenylpyridine
- Purity
- 95%
- Packaging
- 1g
- Price
- $300
- Updated
- 2021/12/16
3-AMINO-4-PHENYLPYRIDINE Chemical Properties,Usage,Production
Synthesis
220952-00-1
146140-99-0
General procedure for the synthesis of 3-amino-4-phenylpyridine from 3-nitro-4-phenylpyridine: 3-nitro-4-phenylpyridine (600 mg, 3.00 mmol) and 10% palladium-carbon catalyst (319 mg, 0.150 mmol) were suspended in methanol (20 mL). The reaction mixture was stirred for 3 h at room temperature under hydrogen atmosphere (1 atm). Upon completion of the reaction, the catalyst was filtered through a diatomaceous earth pad to remove the catalyst. The filtrate was concentrated under reduced pressure to give an off-white solid 3-amino-4-phenylpyridine (420 mg, 2.468 mmol, 82% yield). The structure of the product was confirmed by NMR hydrogen spectroscopy (400 MHz, DMSO-d6): δ 8.11 (s, 1H), 7.85 (d, J = 4.8 Hz, 1H), 7.54-7.47 (m, 4H), 7.45-7.38 (m, 1H), 7.00 (d, J = 4.5 Hz, 1H), 5.10 (br.s., 2H); liquid chromatography-mass spectrometry (ESI) showed m/z 171.1 [(M + H)+, calculated value C11H11N2 171.1].
References
[1] Journal of Heterocyclic Chemistry, 2001, vol. 38, # 1, p. 99 - 104
[2] Angewandte Chemie - International Edition, 2013, vol. 52, # 1, p. 304 - 309
[3] Angew. Chem., 2013, vol. 125, # 1, p. 322 - 327,6
[4] Patent: WO2018/98411, 2018, A1. Location in patent: Page/Page column 85
3-AMINO-4-PHENYLPYRIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
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