ChemicalBook > CAS DataBase List > Baccatine III

Baccatine III

Product Name
Baccatine III
CAS No.
27548-93-2
Chemical Name
Baccatine III
Synonyms
BACCATIN III;NSC 330753;baccatin Ⅲ;Baccatine Ⅲ;BACCATINE III;Bacardine III;Baccatin III-RM;BACCATIN III 98%;Baccatine III,95%;Paclitaxel Impurity N
CBNumber
CB1380992
Molecular Formula
C31H38O11
Formula Weight
586.63
MOL File
27548-93-2.mol
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Baccatine III Property

Melting point:
229-234 °C
Boiling point:
562.81°C (rough estimate)
Density 
1.2062 (rough estimate)
refractive index 
1.5455-1.5475
storage temp. 
Sealed in dry,Store in freezer, under -20°C
solubility 
DMSO : 125 mg/mL (213.08 mM; Need ultrasonic)
form 
Solid
pka
12.76±0.70(Predicted)
color 
White to off-white
Water Solubility 
insoluble
Stability:
4 Year Shelf Life
InChIKey
OVMSOCFBDVBLFW-VHLOTGQHSA-N
SMILES
O1C[C@@]2(OC(C)=O)[C@@]3([H])[C@H](OC(=O)C4=CC=CC=C4)[C@@]4(O)C(C)(C)C(=C(C)[C@@H](O)C4)[C@@H](OC(C)=O)C(=O)[C@]3(C)[C@@H](O)C[C@@]12[H]
CAS DataBase Reference
27548-93-2
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Safety

Hazard Codes 
T
Risk Statements 
45-46-22-36/37/38-48/20/22
Safety Statements 
53-22-26-36/37/39-45-24/25
RIDADR 
1544
WGK Germany 
3
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
29329990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H340May cause genetic defects

H350May cause cancer

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
B8154
Product name
Baccatin III
Purity
≥95% (HPLC)
Packaging
5mg
Price
$205
Updated
2025/07/31
Cayman Chemical
Product number
21404
Product name
Baccatin III
Purity
≥98%
Packaging
5mg
Price
$63
Updated
2024/03/01
Cayman Chemical
Product number
21404
Product name
Baccatin III
Purity
≥98%
Packaging
10mg
Price
$117
Updated
2024/03/01
Cayman Chemical
Product number
21404
Product name
Baccatin III
Purity
≥98%
Packaging
25mg
Price
$275
Updated
2024/03/01
Cayman Chemical
Product number
21404
Product name
Baccatin III
Purity
≥98%
Packaging
50mg
Price
$486
Updated
2024/03/01
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Baccatine III Chemical Properties,Usage,Production

Chemical Properties

White to Off-White Powder

Uses

A precursor to Paclitaxel, a neoplasm inhibitor to ovarian and breast cancers found in Taxus species

Uses

immunomodulator, induces apoptosis

Definition

ChEBI: A tetracyclic diterpenoid isolated from plant species of the genus Taxus.

in vivo

Baccatin III (0.05-0.5 mg/kg; intragastrically; once daily; 17-19 days) significantly inhibits tumor growth and reduced accumulation of myeloid-derived suppressor cells (MDSCs) in BALB/c mice with 4T1 breast cancer or CT26 colon cancer[1].
Baccatin III (5-10 mg/kg; intraperitoneally; single; 21 days) alleviates Bleomycin (HY-108345)-induced lung fibrosis in C57BL/6 mice by inhibiting TGF-β1[2].

Baccatine III Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Baccatine III manufacturers

ShenZhen H&D Pharmaceutical Technology Co., LTD
Product
Paclitaxel EP Impurity N 27548-93-2
Price
US $0.00-0.00/mg
Min. Order
10mg
Purity
0.98
Supply Ability
10g
Release date
2024-04-25
Shanghai Standard Technology Co., Ltd.
Product
Baccatin III 27548-93-2
Price
US $0.00/mg
Min. Order
20mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2020-04-22
Qiuxian Baitai New Material Co., LTD
Product
Baccatin III 27548-93-2
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200000pcs
Release date
2021-03-15

27548-93-2, Baccatine IIIRelated Search:

Paclitaxel ACETYLTAXOL, 7-(P) Cephalomannine 10-Deacetylbaccatin III β-(BenzoylaMino)-α-hydroxybenzenepropanoic Acid (αR,βS)-(1S,3S,4S,4aR,5S,6S,8S,11R,12aS)-3,11-Bis(acetyloxy)-4-[(benzoyloxy)Methyl]-1,2,3,4,4a,5,6,7,8,11,12,12a-dodecahydro-1,4,5,6-tetrahydroxy-9,12a,13,13-tetraMethyl-12-oxo-6,10-Methanobenzocyclodecen-8-yl Ester Paclitaxel EP Impurity I 7-O-(Triethylsilyl) Paclitaxel PACLITAXEL C 7-Epitaxol Paclitaxel IMpurity F N-Debenzoyl-N-[(3E)-hex-3-enoyl]paclitaxel 7-EPI-10-DEACETYLTAXOL 7-EPI-CEPHALOMANNINE Deacetyltaxol Iso CephaloMannine Paclitaxel EP Impurity J Paclitaxel impurity 19/Taxol E/(αR,βS)-α-Hydroxy-β-[[(2S)-2-methyl-1-oxobutyl]amino]benzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetr Paclitaxel IMpurity O

  • BACCATINE III
  • BACCATIN III
  • (1S)-4α,10β-Bis(acetoxy)-2α-(benzoyloxy)-5β,20-epoxy-1,7β,13α-trihydroxytaxa-11-ene-9-one
  • (2aR)-6α,12bβ-Bisacetoxy-12β-(benzoyloxy)-1,2aβ,3,4,4a,6,9,10,11,12,12aβ,12b-dodecahydro-4α,9β,11β-trihydroxy-4aα,8,13,13-tetramethyl-7,11-methano-5H-cyclodeca[3,4]benzo[1,2-b]oxete-5-one
  • (2aR)-6α,12bβ-Diacetoxy-12β-benzoyloxy-1,2aβ,3,4,4a,6,9,10,11,12,12aβ,12b-dodecahydro-4α,9β,11β-trihydroxy-4aα,8,13,13-tetramethyl-7,11α-methano-5H-cyclodeca[3,4]benzo[1,2-b]oxete-5-one
  • 6α,12bβ-Diacetoxy-12β-benzoyloxy-1,2aβ,3,4,4a,6,9,10,11,12,12aβ,12b-dodecahydro-4α,9β,11β-trihydroxy-4aα,8,13,13-tetramethyl-7,11α-methano-5H-cyclodeca[3,4]benzo[1,2-b]oxete-5-one
  • Baccatine III,95%
  • baccatin Ⅲ
  • BACCATIN III 98%
  • (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,9,11-trihydroxy-4a,8,13,13-tetraMethyl-7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one
  • NSC 330753
  • Baccatin III >=95% (HPLC)
  • Paclitaxel EP Impurity N (Baccatin III)
  • Paclitaxel Impurity 14（Paclitaxel EP Impurity N）
  • Paclitaxel EP Impurity N 13-O-de[(2R,3S)-3-(benzoylamino)-2-hydroxy-3- phenylpropanoyl]paclitaxel (baccatin III).
  • 13-O-de[(2R,3S)-3-(benzoylamino)-2-hydroxy-3- phenylpropanoyl]paclitaxel (baccatin III).
  • 7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one,6,12b-bis(acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,9,11-trihydroxy-4a,8,13,13-tetraMethyl-,(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-
  • 13-O-de[(2R,3S)-3-(benzoylamino)-2-hydroxy-3phenylpropanoyl]paclitaxel
  • Paclitaxel EP Impurity N
  • (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12-(Benzoyloxy)-4,9,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxete-6,12b-diyl diacetate
  • Baccatin IIIQ: What is Baccatin III Q: What is the CAS Number of Baccatin III Q: What is the storage condition of Baccatin III Q: What are the applications of Baccatin III
  • Baccatine III,27548-93-2
  • Paclitaxel Impurity N
  • Bacardine III
  • Baccatine Ⅲ
  • Baccatin III-RM
  • (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12-(benzoyloxy)-4,9,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxete-6,12b-di
  • Paclitaxel Imp. N (EP): 13-O-de[(2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenyl propanoyl]paclitaxel
  • (2ar,4s,4as,6r,9s,11s,12s,12ar,12bs)-12-(benzoyloxy)-4,9,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-3,4,4a,5,6,9,10,11,12,12a-decahydro-1h-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxete-6,12b(2ah)-diyl diacetate
  • 27548-93-2
  • C31H38O11
  • Asymmetric Synthesis
  • Chiral Building Blocks
  • Complex Molecules
  • Inhibitors
  • API
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  • Pharmaceuticals
  • Aromatics
  • Chiral Reagents
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