1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol

Product Name: 1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol
CAS No.: 1472-62-4
Chemical Name: 1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol
Synonyms: (+/-)-N-methylcoclaurine;1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol;7-Isoquinolinol, 1,2,3,4-tetrahydro-1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-
CBNumber: CB13823814
Molecular Formula: C18H21NO3
Formula Weight: 299.36
MOL File: 1472-62-4.mol

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1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol Property

Melting point:: 138 °C
Boiling point:: 480.9±45.0 °C(Predicted)
Density: 1.214±0.06 g/cm3(Predicted)
pka: 10.00±0.15(Predicted)
form: Solid
color: Off-white to light yellow

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Hazard and Precautionary Statements (GHS)

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1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol Chemical Properties,Usage,Production

Uses

(±)-N-Methylcoclaurine is a selective α2-adrenoceptor antagonist[1].

References

[1] H H Pauli, et al. Molecular cloning and functional heterologous expression of two alleles encoding (S)-N-methylcoclaurine 3'-hydroxylase (CYP80B1), a new methyl jasmonate-inducible cytochrome P-450-dependent mono-oxygenase of benzylisoquinoline alkaloid biosynthesis. Plant J. 1998 Mar;13(6):793-801. DOI:10.1046/j.1365-313x.1998.00085.x

1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol Preparation Products And Raw materials

Raw materials

Preparation Products

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1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol Suppliers

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1472-62-4, 1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-olRelated Search:

(+)-Coclaurine (-)-1,2,3,4-Tetrahydro-7,8-dimethoxy-1-[(4-methoxyphenyl)methyl]isoquinoline (+)-S-N-Methylcoclaurine Hydrochloride GS 389 N-Methylcoclaurine 6,7-Isoquinolinediol, 1,2,3,4-tetrahydro-1-[(4-methoxyphenyl)methyl]- Demethyl-Coclaurine 1,2,3,4-Tetrahydro-6-methoxy-1-[(4-methoxyphenyl)methyl]-7-isoquinolinol 1,2,3,4-Tetrahydro-7-methoxy-1-[(4-methoxyphenyl)methyl]-6-isoquinolinol N-nitroso Coclaurine

1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol

(+/-)-N-methylcoclaurine

7-Isoquinolinol, 1,2,3,4-tetrahydro-1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-

1472-62-4