(R,S)-ANATABINE
- Product Name
- (R,S)-ANATABINE
- CAS No.
- 2743-90-0
- Chemical Name
- (R,S)-ANATABINE
- Synonyms
- D,L-ANATABINE;rac-Anatabine;(R,S)-ANATABINE;Nicotine USP RC A;ANATABINE, (+/-)-(RG);Nicotine Impurity A as Racemate;1,2,3,6-TETRAHYDRO-2,3'-BIPYRIDINE;Nicotine EP Impurity A as Racemate;1,2,3,6-Tetrahydro-2,3'-bipyridine;Anatabine, froM Nicotiana tabacuM L.
- CBNumber
- CB1382628
- Molecular Formula
- C10H12N2
- Formula Weight
- 160.22
- MOL File
- 2743-90-0.mol
(R,S)-ANATABINE Property
- Boiling point:
- 136
- Density
- 1.045±0.06 g/cm3(Predicted)
- storage temp.
- Amber Vial, Refrigerator, Under Inert Atmosphere
- solubility
- ≤15mg/ml in DMSO;15mg/ml in dimethyl formamide
- form
- solution in ethanol.
- pka
- 8.84±0.40(Predicted)
- color
- Light yellow to yellow
- Stability:
- Hygroscopic, Light Sensitive
- CAS DataBase Reference
- 2743-90-0
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- PHR3060
- Product name
- Nicotine Related Compound A/EP Impurity A
- Purity
- pharmaceutical secondary standard, certified reference material
- Packaging
- 50MG
- Price
- $576
- Updated
- 2024/03/01
- Product number
- 1463326
- Product name
- Nicotine Related Compound A
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 20mg
- Price
- $1380
- Updated
- 2024/03/01
- Product number
- 11001
- Product name
- (R,S)-Anatabine
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $37
- Updated
- 2024/03/01
- Product number
- 11001
- Product name
- (R,S)-Anatabine
- Purity
- ≥95%
- Packaging
- 10mg
- Price
- $62
- Updated
- 2024/03/01
- Product number
- 11001
- Product name
- (R,S)-Anatabine
- Purity
- ≥95%
- Packaging
- 50mg
- Price
- $241
- Updated
- 2024/03/01
(R,S)-ANATABINE Chemical Properties,Usage,Production
Description
(R,S)-Anatabine is a minor alkaloid produced in plants of the Solanaceae family, including tobacco. The detection of (R,S)-anatabine in urine is used as an indicator of tobacco use, particularly when nicotine-
Chemical Properties
Light Yellow Oil
Uses
A nicotine metabolite
Uses
A nicotine (N412420) metabolite.
Uses
(R,S)-Anatabine is a metabolite of Nicotine (N412420).
in vitro
anatabine dose-dependently lowered aβ1-40 and aβ1-42 levels and reduced sappβ production without any effects on sappα levels. anatabine lowered aβ production by mainly impacting the β-cleavage of app. anatabine lowered nfκb activation. anatabine inhibited bace-1 transcription and reduced bace-1 protein levels in human neuronal like shsy-5y cells. (r,s)-anatabine also dose dependently inhibits nf-κb activation [1].
in vivo
in a transgenic mouse model of alzheimer's disease, acute treatment with anatabine for 4 days significantly lowered brain soluble aβ1-40 and aβ1-42 levels [1].
References
[1] paris d, beaulieu-abdelahad d, bachmeier c, et al. anatabine lowers alzheimer's aβ production in vitro and in vivo[j]. european journal of pharmacology, 2011, 670(2): 384-391.
(R,S)-ANATABINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from (R,S)-ANATABINE manufacturers
- Product
- (R,S)-ANATABINE 2743-90-0
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- 95%min
- Supply Ability
- 20kg/month
- Release date
- 2019-12-20