METHYL 2-CHLORO-3-NITROBENZOATE
- Product Name
- METHYL 2-CHLORO-3-NITROBENZOATE
- CAS No.
- 53553-14-3
- Chemical Name
- METHYL 2-CHLORO-3-NITROBENZOATE
- Synonyms
- METHYL 2-CHLORO-3-NITROBENZOATE;Benzoic acid, 2-chloro-3-nitro-, methyl ester
- CBNumber
- CB1382976
- Molecular Formula
- C8H6ClNO4
- Formula Weight
- 215.59
- MOL File
- 53553-14-3.mol
METHYL 2-CHLORO-3-NITROBENZOATE Property
- Melting point:
- 70 °C
- Boiling point:
- 319.5±22.0 °C(Predicted)
- Density
- 1.426±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- Appearance
- Light yellow to yellow Solid
Safety
- HS Code
- 2916399090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- B499288
- Product name
- methyl2-chloro-3-nitrobenzoate
- Packaging
- 100mg
- Price
- $90
- Updated
- 2021/12/16
- Product number
- FC55358
- Product name
- 2-Chloro-3-nitrobenzoic acid methyl ester
- Packaging
- 1g
- Price
- $95
- Updated
- 2021/12/16
- Product number
- 7382AH
- Product name
- Methyl2-chloro-3-nitrobenzoate
- Packaging
- 250mg
- Price
- $99
- Updated
- 2021/12/16
- Product number
- FC55358
- Product name
- 2-Chloro-3-nitrobenzoic acid methyl ester
- Packaging
- 2g
- Price
- $150
- Updated
- 2021/12/16
- Product number
- 7382AH
- Product name
- Methyl2-chloro-3-nitrobenzoate
- Packaging
- 1g
- Price
- $163
- Updated
- 2021/12/16
METHYL 2-CHLORO-3-NITROBENZOATE Chemical Properties,Usage,Production
Uses
Methyl 2-Chloro-3-nitrobenzoate is a useful research chemical used in the preparation of benzothiadiazole derivatives as agrochemical microbicides.
Synthesis
67-56-1
3970-35-2
53553-14-3
General procedure for the synthesis of methyl 2-chloro-3-nitrobenzoate from methanol and 2-chloro-3-nitrobenzoic acid: 1. to a solution of 2-chloro-3-nitrobenzoic acid (10.0 g, 49.6 mmol) in methanol (80 mL) was added concentrated sulfuric acid (2.0 mL). 2. The reaction mixture was stirred overnight under reflux conditions. 3. Upon completion of the reaction, the methanol was removed by vacuum concentration. 4. Water was added to the residue and extracted with ethyl acetate. 5. The organic phase was washed sequentially with water, saturated sodium bicarbonate solution and saturated brine. 6. 6. The organic phase was dried with magnesium sulfate. 7. The target compound, methyl 2-chloro-3-nitrobenzoate (10.6 g, 99% yield), was obtained as a white solid by vacuum concentration. 8. The product was characterized by 1H NMR (CDCl3) and HPLC: 1H NMR (CDCl3) δ (ppm): 7.95 (dd, 1H), 7.84 (dd, 1H), 7.48 (t, 1H), 3.98 (s, 3H). HPLC Rt = 11.88 min. 150 × 6.0 mm); mobile phase: 0-20 min, acetonitrile/water = 10/90 to 100/0 (gradient), 20-30 min, acetonitrile/water = 100/0 (isocratic); flow rate: 1 mL/min.
References
[1] Patent: WO2008/51533, 2008, A2. Location in patent: Page/Page column 95
[2] Pesticide Science, 1997, vol. 50, # 4, p. 275 - 282
[3] Patent: EP1982982, 2008, A1. Location in patent: Page/Page column 197
[4] Patent: EP2141150, 2010, A1. Location in patent: Page/Page column 109-110
[5] Patent: KR101511396, 2015, B1. Location in patent: Paragraph 2881-2885
METHYL 2-CHLORO-3-NITROBENZOATE Preparation Products And Raw materials
Raw materials
Preparation Products
METHYL 2-CHLORO-3-NITROBENZOATE Suppliers
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- sales@ajchem.in
- Country
- India
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- info@chemsworth.com
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View Lastest Price from METHYL 2-CHLORO-3-NITROBENZOATE manufacturers
- Product
- METHYL 2-CHLORO-3-NITROBENZOATE 53553-14-3
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 97.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-05-12