2-AMINO-2-NORBORNANECARBOXYLIC ACID

Product Name: 2-AMINO-2-NORBORNANECARBOXYLIC ACID
CAS No.: 20448-79-7
Chemical Name: 2-AMINO-2-NORBORNANECARBOXYLIC ACID
Synonyms: BCH;B-Bch;LAT1-IN-1;LAT1-IN-1 (BCH);2-AMINO-2-NORBORNANECARBOXYLIC ACID;2-Aminonorbornane-2-carboxylic acid;2-Amino-2-carboxy-bicyclo-2,2,1-heptane;2-AMINOBICYCLO[2.2.1]HEPTANE-2-CARBOXYLIC ACID;3-amino-3-bicyclo[2.2.1]heptanecarboxylic acid;3-aminobicyclo[2.2.1]heptane-3-carboxylic Acid
CBNumber: CB1384309
Molecular Formula: C8H13NO2
Formula Weight: 155.19
MOL File: 20448-79-7.mol

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2-AMINO-2-NORBORNANECARBOXYLIC ACID Property

Melting point:: >300 °C(lit.)
Boiling point:: 295.5±23.0 °C(Predicted)
Density: 1.256±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: Aqueous Acid (Slightly)
form: Solid
pka: 2.58±0.20(Predicted)
color: White
Water Solubility: Soluble to 100 mM in water
CAS DataBase Reference: 20448-79-7(CAS DataBase Reference)

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: A7902
Product name: 2-Amino-2-norbornanecarboxylic acid
Purity: amino acid transport inhibitor
Packaging: 100mg
Price: $117
Updated: 2024/03/01

Sigma-Aldrich

Product number: A7902
Product name: 2-Amino-2-norbornanecarboxylic acid
Purity: amino acid transport inhibitor
Packaging: 1g
Price: $662
Updated: 2024/03/01

Cayman Chemical

Product number: 15249
Product name: BCH
Purity: ≥98%
Packaging: 25mg
Price: $33
Updated: 2024/03/01

Cayman Chemical

Product number: 15249
Product name: BCH
Purity: ≥98%
Packaging: 50mg
Price: $63
Updated: 2024/03/01

Sigma-Aldrich

Product number: A7902
Product name: 2-Amino-2-norbornanecarboxylic acid
Purity: amino acid transport inhibitor
Packaging: 250mg
Price: $219
Updated: 2024/03/01

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2-AMINO-2-NORBORNANECARBOXYLIC ACID Chemical Properties,Usage,Production

Uses

2-Amino-2-norbornanecarboxylic Acid functions in the suppressive effect of I-type amino acid transporter 1 inhibition as therapeutic target on human esophageal squamous cell carcinoma. Also use in the design and preparation of KMH-233, selective and slowly reversible inhibitor of L-type amino acid transporter 1 (LAT1) which potentiates antiproliferative drug efficacy in cancer cells

Definition

ChEBI: 2-Amino-2-norbornanecarboxylic acid is a monoterpenoid.

General Description

2-Amino-2-norbornanecarboxylic acid is a potential large amino acid transporters inhibitor. It may suppress tumor progression and apoptosis.

Biochem/physiol Actions

2-Amino-2-norbornanecarboxylic acid (BCH) is a Na(+)-independent system L specific substrate used with other system specific substrates such as the system A specific substrate α-(methylamino) isobutyric acid and system N specific substrate L-glutamic acid gamma-monohydroxamate to help identify, differentiate and characterize amino acid transport systems in cells.

storage

Store at RT

2-AMINO-2-NORBORNANECARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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2-AMINO-2-NORBORNANECARBOXYLIC ACID Suppliers

China 45 Germany 1 India 1 South Korea 1 Switzerland 1 United Kingdom 6 United States 14 USA 1 Global 70

3B Pharmachem (Wuhan) International Co.,Ltd.

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20448-79-7, 2-AMINO-2-NORBORNANECARBOXYLIC ACIDRelated Search:

3-AMINOPENTANE-3-CARBOXYLIC ACID DL-ALPHA-METHYLLEUCINE BICYCLO[2.2.1]HEPTANE-2-CARBOXYLIC ACID 1-Amino-1-cyclohexanecarboxylic acid Cycloleucine 3-Cyclopentylpropionic acid Heptane 1-AMINO-2-METHYLCYCLOHEXANECARBOXYLIC ACID 2-AMINO-3-METHYL-HEXANOIC ACID 2-AMINO-3-ETHYL-PENTANOIC ACID (R/S)-2-AMINO-5-METHYLHEXANOIC ACID NORBORNANE-2-CARBOXALDEHYDE 2-amino-3-cyclopentylpropanoic acid DIPROPYLGLYCINE 2-AMINO-2-METHYLPENTANOIC ACID 2-AMINO-2-NORBORNANECARBOXYLIC ACID 1-AMINO-3-METHYLCYCLOHEXANECARBOXYLIC ACID CYCLOLEUCINOL

2-AMINO-2-NORBORNANECARBOXYLIC ACID

2-AMINOBICYCLO[2.2.1]HEPTANE-2-CARBOXYLIC ACID

BCH

2-AMINO-2-NORBORNANECARBOXYLIC ACID, 98% , MIXTURE OF ISOMERS

2-Amino-2-carboxy-bicyclo-2,2,1-heptane

2-Aminonorbornane-2-carboxylic acid

B-Bch

Bicyclo(2.2.1)heptane-2-carboxylic acid, 2-amino-

2-AMino-2-norbornanecarboxylic acid aMino acid transport inhibitor

LAT1-IN-1 (BCH)

LAT1-IN-1

3-amino-3-bicyclo[2.2.1]heptanecarboxylic acid

3-aminobicyclo[2.2.1]heptane-3-carboxylic Acid

LAT-1-IN-1,inhibit,LAT1 IN 1,LAT1IN1,Apoptosis,Inhibitor

20448-79-7

Biochemicals and Reagents

BioChemical

Amino Acids and Peptides

A - H

Modified Amino Acids

Peptide Synthesis

Others

Specialty Synthesis

Unnatural Amino Acid Derivatives