2-AMINO-2-NORBORNANECARBOXYLIC ACID
- Product Name
- 2-AMINO-2-NORBORNANECARBOXYLIC ACID
- CAS No.
- 20448-79-7
- Chemical Name
- 2-AMINO-2-NORBORNANECARBOXYLIC ACID
- Synonyms
- BCH;B-Bch;LAT1-IN-1;LAT1-IN-1 (BCH);2-AMINO-2-NORBORNANECARBOXYLIC ACID;2-Aminonorbornane-2-carboxylic acid;2-Amino-2-carboxy-bicyclo-2,2,1-heptane;2-AMINOBICYCLO[2.2.1]HEPTANE-2-CARBOXYLIC ACID;3-amino-3-bicyclo[2.2.1]heptanecarboxylic acid;3-aminobicyclo[2.2.1]heptane-3-carboxylic Acid
- CBNumber
- CB1384309
- Molecular Formula
- C8H13NO2
- Formula Weight
- 155.19
- MOL File
- 20448-79-7.mol
2-AMINO-2-NORBORNANECARBOXYLIC ACID Property
- Melting point:
- >300 °C(lit.)
- Boiling point:
- 295.5±23.0 °C(Predicted)
- Density
- 1.256±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- Aqueous Acid (Slightly)
- form
- Solid
- pka
- 2.58±0.20(Predicted)
- color
- White
- Water Solubility
- Soluble to 100 mM in water
- CAS DataBase Reference
- 20448-79-7(CAS DataBase Reference)
Safety
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A7902
- Product name
- 2-Amino-2-norbornanecarboxylic acid
- Purity
- amino acid transport inhibitor
- Packaging
- 100mg
- Price
- $117
- Updated
- 2024/03/01
- Product number
- A7902
- Product name
- 2-Amino-2-norbornanecarboxylic acid
- Purity
- amino acid transport inhibitor
- Packaging
- 1g
- Price
- $662
- Updated
- 2024/03/01
- Product number
- 15249
- Product name
- BCH
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $33
- Updated
- 2024/03/01
- Product number
- 15249
- Product name
- BCH
- Purity
- ≥98%
- Packaging
- 50mg
- Price
- $63
- Updated
- 2024/03/01
- Product number
- A7902
- Product name
- 2-Amino-2-norbornanecarboxylic acid
- Purity
- amino acid transport inhibitor
- Packaging
- 250mg
- Price
- $219
- Updated
- 2024/03/01
2-AMINO-2-NORBORNANECARBOXYLIC ACID Chemical Properties,Usage,Production
Uses
2-Amino-2-norbornanecarboxylic Acid functions in the suppressive effect of I-type amino acid transporter 1 inhibition as therapeutic target on human esophageal squamous cell carcinoma. Also use in the design and preparation of KMH-233, selective and slowly reversible inhibitor of L-type amino acid transporter 1 (LAT1) which potentiates antiproliferative drug efficacy in cancer cells
Definition
ChEBI: 2-Amino-2-norbornanecarboxylic acid is a monoterpenoid.
General Description
2-Amino-2-norbornanecarboxylic acid is a potential large amino acid transporters inhibitor. It may suppress tumor progression and apoptosis.
Biochem/physiol Actions
2-Amino-2-norbornanecarboxylic acid (BCH) is a Na(+)-independent system L specific substrate used with other system specific substrates such as the system A specific substrate α-(methylamino) isobutyric acid and system N specific substrate L-glutamic acid gamma-monohydroxamate to help identify, differentiate and characterize amino acid transport systems in cells.
storage
Store at RT