ChemicalBook > CAS DataBase List > 2-AMINO-2-NORBORNANECARBOXYLIC ACID

2-AMINO-2-NORBORNANECARBOXYLIC ACID

Product Name
2-AMINO-2-NORBORNANECARBOXYLIC ACID
CAS No.
20448-79-7
Chemical Name
2-AMINO-2-NORBORNANECARBOXYLIC ACID
Synonyms
BCH;B-Bch;LAT1-IN-1;LAT1-IN-1 (BCH);2-AMINO-2-NORBORNANECARBOXYLIC ACID;2-Aminonorbornane-2-carboxylic acid;2-Amino-2-carboxy-bicyclo-2,2,1-heptane;2-AMINOBICYCLO[2.2.1]HEPTANE-2-CARBOXYLIC ACID;3-amino-3-bicyclo[2.2.1]heptanecarboxylic acid;3-aminobicyclo[2.2.1]heptane-3-carboxylic Acid
CBNumber
CB1384309
Molecular Formula
C8H13NO2
Formula Weight
155.19
MOL File
20448-79-7.mol
More
Less

2-AMINO-2-NORBORNANECARBOXYLIC ACID Property

Melting point:
>300 °C(lit.)
Boiling point:
295.5±23.0 °C(Predicted)
Density 
1.256±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Aqueous Acid (Slightly)
form 
Solid
pka
2.58±0.20(Predicted)
color 
White
Water Solubility 
Soluble to 100 mM in water
CAS DataBase Reference
20448-79-7(CAS DataBase Reference)
More
Less

Safety

WGK Germany 
3
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A7902
Product name
2-Amino-2-norbornanecarboxylic acid
Purity
amino acid transport inhibitor
Packaging
100mg
Price
$117
Updated
2024/03/01
Sigma-Aldrich
Product number
A7902
Product name
2-Amino-2-norbornanecarboxylic acid
Purity
amino acid transport inhibitor
Packaging
1g
Price
$662
Updated
2024/03/01
Cayman Chemical
Product number
15249
Product name
BCH
Purity
≥98%
Packaging
25mg
Price
$33
Updated
2024/03/01
Cayman Chemical
Product number
15249
Product name
BCH
Purity
≥98%
Packaging
50mg
Price
$63
Updated
2024/03/01
Sigma-Aldrich
Product number
A7902
Product name
2-Amino-2-norbornanecarboxylic acid
Purity
amino acid transport inhibitor
Packaging
250mg
Price
$219
Updated
2024/03/01
More
Less

2-AMINO-2-NORBORNANECARBOXYLIC ACID Chemical Properties,Usage,Production

Uses

2-Amino-2-norbornanecarboxylic Acid functions in the suppressive effect of I-type amino acid transporter 1 inhibition as therapeutic target on human esophageal squamous cell carcinoma. Also use in the design and preparation of KMH-233, selective and slowly reversible inhibitor of L-type amino acid transporter 1 (LAT1) which potentiates antiproliferative drug efficacy in cancer cells

Definition

ChEBI: 2-Amino-2-norbornanecarboxylic acid is a monoterpenoid.

General Description

2-Amino-2-norbornanecarboxylic acid is a potential large amino acid transporters inhibitor. It may suppress tumor progression and apoptosis.

Biochem/physiol Actions

2-Amino-2-norbornanecarboxylic acid (BCH) is a Na(+)-independent system L specific substrate used with other system specific substrates such as the system A specific substrate α-(methylamino) isobutyric acid and system N specific substrate L-glutamic acid gamma-monohydroxamate to help identify, differentiate and characterize amino acid transport systems in cells.

storage

Store at RT

2-AMINO-2-NORBORNANECARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

2-AMINO-2-NORBORNANECARBOXYLIC ACID Suppliers

China 49 Germany 1 India 1 South Korea 1 Switzerland 1 United Kingdom 6 United States 15 USA 1 Global 75
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Guangzhou Isun Pharmaceutical Co., Ltd
Tel
020-39119399 18927568969
Fax
020-39119999
Email
isunpharm@qq.com
Country
China
ProdList
4674
Advantage
55
Amatek Scientific Co. Ltd.
Tel
0512-56316828 4008675858
Fax
+86-512-56316826
Email
sales@amateksci.com
Country
China
ProdList
9894
Advantage
55
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 4009686088
Email
3193328036@qq.com
Country
China
ProdList
29785
Advantage
68
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
Advantage
58
Aikon International Limited
Tel
025-58859352 18068836627
Fax
02557626880
Email
sales01@aikonchem.com
Country
China
ProdList
15084
Advantage
58
Beijing Minruida Technology Co., Ltd.
Tel
010-82387566 18001021521;
Fax
82387566-801
Email
sales@mreda.com.cn
Country
China
ProdList
10789
Advantage
58
Chengdu Feibai Pharmaceutical Co., Ltd.
Tel
028-84641798 18782128315
Email
3302391190@qq.com
Country
China
ProdList
9220
Advantage
55
Hangzhou Synstar pharmaceutical Technology CO.,Ltd
Tel
0571-85361029
Fax
0571-85361029
Email
synstar518@163.com
Country
China
ProdList
1990
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58
Shanghai hongqu biomedical technology co. LTD
Tel
88888888888
Email
hongquchem@qq.com
Country
China
ProdList
5132
Advantage
58
MedBioPharmaceutical Technology Inc
Tel
021-69568360 18916172912
Email
order@med-bio.cn
Country
China
ProdList
8140
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing@energy-chemical.com
Country
China
ProdList
44918
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223;
Email
psaitong@jm-bio.com
Country
China
ProdList
29774
Advantage
58
Shanghai Taopu Industrial Co., LTD
Tel
159-00573766 18018507602
Email
394643792@qq.com
Country
China
ProdList
4211
Advantage
58
Hu' nan Yunbang Pharmaceutical Co., Ltd.
Tel
0731-85561037 15386497078
Email
yunbang@yunbangapi.com
Country
China
ProdList
4819
Advantage
58
Bide Pharmatech Ltd.
Tel
400-1647117 13681763483
Email
product02@bidepharm.com
Country
China
ProdList
62075
Advantage
58
Kaifeng Mingren Pharmaceutical Co.,LTD
Tel
0371-65741762
Fax
QQ：2860768577
Email
sales@hasunny.com
Country
China
ProdList
2380
Advantage
58
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
18621169109
Email
market03@meryer.com
Country
China
ProdList
27987
Advantage
58
Suzhou Haiben Pharmaceutical Co., Ltd
Tel
14760821013 13564957716
Email
1816280386@qq.com
Country
China
ProdList
7992
Advantage
58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd
Tel
021-59167510 18117107507
Email
vip@med-life.cn
Country
China
ProdList
4997
Advantage
58
Nanjing Shizhou Biology Technology Co.,Ltd
Tel
025-85560043 15850508050
Fax
025-85563444
Email
cindy.huang@synzest.com
Country
China
ProdList
12000
Advantage
58
Shanghai Aladdin Biochemical Technology Co.,Ltd.
Tel
+86-18521732826
Email
market@aladdin-e.com
Country
China
ProdList
48461
Advantage
58
RD International Technology Co., Limited
Tel
18024082417
Email
market@ubiochem.com
Country
China
ProdList
9266
Advantage
58
Shaanxi Xihua Chemical Industry Co., Ltd
Tel
17691182729 13992773979
Email
1049@dideu.com
Country
China
ProdList
8150
Advantage
58
Hubei Danding Pharmaceutical Technology Co., Ltd
Tel
18917019315 18917019315
Email
18917019315@163.cn
Country
China
ProdList
9159
Advantage
58
Hebei Weibang Biotechnology Co., Ltd
Tel
+8615350571055
Email
Sibel@weibangbio.com
Country
China
ProdList
6087
Advantage
58
LEAPCHEM CO., LTD.
Tel
+86-852-30606658
Email
market18@leapchem.com
Country
China
ProdList
43340
Advantage
58
Wuhan Topule Biopharmaceutical Co., Ltd
Tel
+8618327326525
Email
masar@topule.com
Country
China
ProdList
8467
Advantage
58
Hangzhou MolCore BioPharmatech Co.,Ltd.
Tel
+86-057181025280; +8617767106207
Fax
0571-85806285
Email
sales@molcore.com
Country
China
ProdList
49734
Advantage
58
Shanghai Gantu Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
1920192055@qq.com
Country
CHINA
ProdList
1843
Advantage
58
Shanghai Hao Zhun Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
info@zzsrm.com
Country
CHINA
ProdList
6650
Advantage
58
Shanghai Haoran Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
470003480@QQ.COM
Country
CHINA
ProdList
6955
Advantage
58
Shanghai Hao Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
market@xlswkj.com
Country
CHINA
ProdList
6793
Advantage
58
Shanghai Weiwei Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
sales@wheybio.com
Country
CHINA
ProdList
4398
Advantage
58
Beijing Bolide Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
1985563437@qq.com
Country
CHINA
ProdList
6158
Advantage
58
Shanghai Benrui Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
john.st@163.com
Country
CHINA
ProdList
1471
Advantage
58
Shanghai Chaoyan Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
471161314@qq.com
Country
CHINA
ProdList
6210
Advantage
58
Shanghai Haoyang Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
596799915@QQ.COM
Country
CHINA
ProdList
2905
Advantage
58
Shenzhen Xinbosheng Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
service@neobioscience.com
Country
CHINA
ProdList
6151
Advantage
58
Boao Pike
Tel
--
Fax
--
Email
lyn@biopike.com.cn
Country
CHINA
ProdList
6629
Advantage
58
Shanghai Fchemicals Technology Co., Ltd
Tel
--
Fax
--
Email
hqliang@fchemicals.com
Country
China
ProdList
4375
Advantage
47
Guangzhou WeiBo Chemical Co., Ltd.
Tel
--
Fax
--
Email
weibochem@163.com
Country
China
ProdList
6187
Advantage
67
Shanghai PI Chemicals Ltd.
Tel
--
Fax
--
Email
sales@pipharm.com
Country
China
ProdList
6344
Advantage
56
Advanced Technology & Industrial Co., Ltd.
Tel
--
Fax
--
Email
sales@advtechind.com
Country
China
ProdList
6523
Advantage
75

20448-79-7, 2-AMINO-2-NORBORNANECARBOXYLIC ACIDRelated Search:

3-AMINOPENTANE-3-CARBOXYLIC ACID DL-ALPHA-METHYLLEUCINE BICYCLO[2.2.1]HEPTANE-2-CARBOXYLIC ACID 1-Amino-1-cyclohexanecarboxylic acid Cycloleucine 3-Cyclopentylpropionic acid Heptane 1-AMINO-2-METHYLCYCLOHEXANECARBOXYLIC ACID 2-AMINO-3-METHYL-HEXANOIC ACID 2-AMINO-3-ETHYL-PENTANOIC ACID (R/S)-2-AMINO-5-METHYLHEXANOIC ACID NORBORNANE-2-CARBOXALDEHYDE 2-amino-3-cyclopentylpropanoic acid DIPROPYLGLYCINE 2-AMINO-2-METHYLPENTANOIC ACID 2-AMINO-2-NORBORNANECARBOXYLIC ACID 1-AMINO-3-METHYLCYCLOHEXANECARBOXYLIC ACID CYCLOLEUCINOL

  • 2-AMINO-2-NORBORNANECARBOXYLIC ACID
  • 2-AMINOBICYCLO[2.2.1]HEPTANE-2-CARBOXYLIC ACID
  • BCH
  • 2-AMINO-2-NORBORNANECARBOXYLIC ACID, 98% , MIXTURE OF ISOMERS
  • 2-Amino-2-carboxy-bicyclo-2,2,1-heptane
  • 2-Aminonorbornane-2-carboxylic acid
  • B-Bch
  • Bicyclo(2.2.1)heptane-2-carboxylic acid, 2-amino-
  • 2-AMino-2-norbornanecarboxylic acid aMino acid transport inhibitor
  • LAT1-IN-1 (BCH)
  • LAT1-IN-1
  • 3-amino-3-bicyclo[2.2.1]heptanecarboxylic acid
  • 3-aminobicyclo[2.2.1]heptane-3-carboxylic Acid
  • LAT-1-IN-1,inhibit,LAT1 IN 1,LAT1IN1,Apoptosis,Inhibitor
  • 20448-79-7
  • Biochemicals and Reagents
  • BioChemical
  • Amino Acids and Peptides
  • A - H
  • Modified Amino Acids
  • Peptide Synthesis
  • Others
  • Specialty Synthesis
  • Unnatural Amino Acid Derivatives