ChemicalBook > CAS DataBase List > 2-AMINO-2-NORBORNANECARBOXYLIC ACID

2-AMINO-2-NORBORNANECARBOXYLIC ACID

Product Name
2-AMINO-2-NORBORNANECARBOXYLIC ACID
CAS No.
20448-79-7
Chemical Name
2-AMINO-2-NORBORNANECARBOXYLIC ACID
Synonyms
BCH;B-Bch;LAT1-IN-1;LAT1-IN-1 (BCH);2-AMINO-2-NORBORNANECARBOXYLIC ACID;2-Aminonorbornane-2-carboxylic acid;2-Amino-2-carboxy-bicyclo-2,2,1-heptane;2-AMINOBICYCLO[2.2.1]HEPTANE-2-CARBOXYLIC ACID;3-amino-3-bicyclo[2.2.1]heptanecarboxylic acid;3-aminobicyclo[2.2.1]heptane-3-carboxylic Acid
CBNumber
CB1384309
Molecular Formula
C8H13NO2
Formula Weight
155.19
MOL File
20448-79-7.mol
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2-AMINO-2-NORBORNANECARBOXYLIC ACID Property

Melting point:
>300 °C(lit.)
Boiling point:
295.5±23.0 °C(Predicted)
Density 
1.256±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Aqueous Acid (Slightly)
form 
Solid
pka
2.58±0.20(Predicted)
color 
White
Water Solubility 
Soluble to 100 mM in water
CAS DataBase Reference
20448-79-7(CAS DataBase Reference)
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A7902
Product name
2-Amino-2-norbornanecarboxylic acid
Purity
amino acid transport inhibitor
Packaging
100mg
Price
$117
Updated
2024/03/01
Sigma-Aldrich
Product number
A7902
Product name
2-Amino-2-norbornanecarboxylic acid
Purity
amino acid transport inhibitor
Packaging
1g
Price
$662
Updated
2024/03/01
Cayman Chemical
Product number
15249
Product name
BCH
Purity
≥98%
Packaging
25mg
Price
$33
Updated
2024/03/01
Cayman Chemical
Product number
15249
Product name
BCH
Purity
≥98%
Packaging
50mg
Price
$63
Updated
2024/03/01
Sigma-Aldrich
Product number
A7902
Product name
2-Amino-2-norbornanecarboxylic acid
Purity
amino acid transport inhibitor
Packaging
250mg
Price
$219
Updated
2024/03/01
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2-AMINO-2-NORBORNANECARBOXYLIC ACID Chemical Properties,Usage,Production

Uses

2-Amino-2-norbornanecarboxylic Acid functions in the suppressive effect of I-type amino acid transporter 1 inhibition as therapeutic target on human esophageal squamous cell carcinoma. Also use in the design and preparation of KMH-233, selective and slowly reversible inhibitor of L-type amino acid transporter 1 (LAT1) which potentiates antiproliferative drug efficacy in cancer cells

Definition

ChEBI: 2-Amino-2-norbornanecarboxylic acid is a monoterpenoid.

General Description

2-Amino-2-norbornanecarboxylic acid is a potential large amino acid transporters inhibitor. It may suppress tumor progression and apoptosis.

Biochem/physiol Actions

2-Amino-2-norbornanecarboxylic acid (BCH) is a Na(+)-independent system L specific substrate used with other system specific substrates such as the system A specific substrate α-(methylamino) isobutyric acid and system N specific substrate L-glutamic acid gamma-monohydroxamate to help identify, differentiate and characterize amino acid transport systems in cells.

storage

Store at RT

2-AMINO-2-NORBORNANECARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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2-AMINO-2-NORBORNANECARBOXYLIC ACID Suppliers

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20448-79-7, 2-AMINO-2-NORBORNANECARBOXYLIC ACIDRelated Search:

3-AMINOPENTANE-3-CARBOXYLIC ACID DL-ALPHA-METHYLLEUCINE BICYCLO[2.2.1]HEPTANE-2-CARBOXYLIC ACID 1-Amino-1-cyclohexanecarboxylic acid Cycloleucine 3-Cyclopentylpropionic acid Heptane 1-AMINO-2-METHYLCYCLOHEXANECARBOXYLIC ACID 2-AMINO-3-METHYL-HEXANOIC ACID 2-AMINO-3-ETHYL-PENTANOIC ACID (R/S)-2-AMINO-5-METHYLHEXANOIC ACID NORBORNANE-2-CARBOXALDEHYDE 2-amino-3-cyclopentylpropanoic acid DIPROPYLGLYCINE 2-AMINO-2-METHYLPENTANOIC ACID 2-AMINO-2-NORBORNANECARBOXYLIC ACID 1-AMINO-3-METHYLCYCLOHEXANECARBOXYLIC ACID CYCLOLEUCINOL

  • 2-AMINO-2-NORBORNANECARBOXYLIC ACID
  • 2-AMINOBICYCLO[2.2.1]HEPTANE-2-CARBOXYLIC ACID
  • BCH
  • 2-AMINO-2-NORBORNANECARBOXYLIC ACID, 98% , MIXTURE OF ISOMERS
  • 2-Amino-2-carboxy-bicyclo-2,2,1-heptane
  • 2-Aminonorbornane-2-carboxylic acid
  • B-Bch
  • Bicyclo(2.2.1)heptane-2-carboxylic acid, 2-amino-
  • 2-AMino-2-norbornanecarboxylic acid aMino acid transport inhibitor
  • LAT1-IN-1 (BCH)
  • LAT1-IN-1
  • 3-amino-3-bicyclo[2.2.1]heptanecarboxylic acid
  • 3-aminobicyclo[2.2.1]heptane-3-carboxylic Acid
  • LAT-1-IN-1,inhibit,LAT1 IN 1,LAT1IN1,Apoptosis,Inhibitor
  • 20448-79-7
  • Biochemicals and Reagents
  • BioChemical
  • Amino Acids and Peptides
  • A - H
  • Modified Amino Acids
  • Peptide Synthesis
  • Others
  • Specialty Synthesis
  • Unnatural Amino Acid Derivatives