ChemicalBook > CAS DataBase List > 2',4'-Dihydroxy-2-phenylacetophenone

2',4'-Dihydroxy-2-phenylacetophenone

Product Name
2',4'-Dihydroxy-2-phenylacetophenone
CAS No.
3669-41-8
Chemical Name
2',4'-Dihydroxy-2-phenylacetophenone
Synonyms
AURORA 15288;TIMTEC-BB SBB008378;OTAVA-BB BB0107930004;2,4-Dihydroxydeoxybenzoin;ALPHA-PHENYLRESACETOPHENONE;BENZYL 2,4-DIHYDROXYPHENYL KETONE;4'-Dihydroxy-2-phenylacetophenone;α-Phenyl-2',4'-dihydroxyacetophenone;2',4'-Dihydroxy-α-phenylacetophenone;2',4'-DIHYDROXY-2-PHENYLACETOPHENONE
CBNumber
CB1387315
Molecular Formula
C14H12O3
Formula Weight
228.24
MOL File
3669-41-8.mol
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2',4'-Dihydroxy-2-phenylacetophenone Property

Melting point:
112-116 °C(lit.)
Boiling point:
225°C/10mmHg(lit.)
Density 
1.278±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
soluble in Methanol
form 
powder to crystal
pka
7.74±0.35(Predicted)
color 
White to Light yellow to Light orange
CAS DataBase Reference
3669-41-8(CAS DataBase Reference)
NIST Chemistry Reference
2,4-Dihydroxyphenylbenzyl ketone(3669-41-8)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39
WGK Germany 
3
HS Code 
29145000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
438499
Product name
Benzyl 2,4-dihydroxyphenyl ketone
Purity
97%
Packaging
1g
Price
$36.9
Updated
2023/06/20
TCI Chemical
Product number
B3921
Product name
Benzyl 2,4-Dihydroxyphenyl Ketone
Purity
>98.0%(GC)
Packaging
5g
Price
$75
Updated
2023/06/20
TCI Chemical
Product number
B3921
Product name
Benzyl 2,4-Dihydroxyphenyl Ketone
Purity
>98.0%(GC)
Packaging
25g
Price
$266
Updated
2021/12/16
TRC
Product number
D452508
Product name
1-(2,4-Dihydroxyphenyl)-2-phenylethanone
Packaging
100mg
Price
$60
Updated
2021/12/16
TRC
Product number
D452508
Product name
1-(2,4-Dihydroxyphenyl)-2-phenylethanone
Packaging
500mg
Price
$75
Updated
2021/12/16
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2',4'-Dihydroxy-2-phenylacetophenone Chemical Properties,Usage,Production

Chemical Properties

off-white crystalline powder

Uses

1-(2,4-Dihydroxyphenyl)-2-phenylethanone is used in preparation of substituted pyrazoles, pyrimidines, triazoles and related heterocycles as c-MYC targeting agents for treatment of cancer and other proliferative diseases.

Preparation

Preparation by Friedel–Crafts acylation of resorcinol with phenylacetyl chloride in the presence of aluminium chloride,
? in methylene chloride (85%) ;
? in nitrobenzene at 70–80° for 15 min (<80%), at r.t. for 24 h (63%) or for 2 days (60%);
? in ethyl ether at r.t. for 24 h (43%).

2',4'-Dihydroxy-2-phenylacetophenone Preparation Products And Raw materials

Raw materials

Preparation Products

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2',4'-Dihydroxy-2-phenylacetophenone Suppliers

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3669-41-8, 2',4'-Dihydroxy-2-phenylacetophenoneRelated Search:


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