(+)-DIOP

Product Name: (+)-DIOP
CAS No.: 37002-48-5
Chemical Name: (+)-DIOP
Synonyms: (S)-DIOP;(+)-DIOP;(+)-DIOP;(S,S)-DIOP;idene-2,3-butanedioL;phosphino)-2,3-O-isopropyL;(2S,3S)-(+)-1,4-Bis(diphenyL;(4S,5S)-(+)-4,5-BIS(DIPHENYLPHOSPHINOMET;4,5-bis(diphenylphosphinomethyl)-2,2-dimethyl-1,3-dioxalan;(+)-2,2-dimethyl-4,5-((diphenylphosphino)dimethyl)dioxolane
CBNumber: CB1393749
Molecular Formula: C31H32O2P2
Formula Weight: 498.54
MOL File: 37002-48-5.mol

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(+)-DIOP Property

Melting point:: 86-88 °C(lit.)
alpha: +26° (c 2.0, CHCl3)
Boiling point:: 590.3±25.0 °C(Predicted)
storage temp.: Store below +30°C.
form: Powder
color: White
optical activity: 28.6°(C=0.01g/ml DCM)
Water Solubility: Sparingly soluble in water at 25°C 2.1E-5 g/L.
Sensitive: Air Sensitive
BRN: 1630280
InChIKey: VCHDBLPQYJAQSQ-LOYHVIPDSA-N
SMILES: P(C1C=CC=CC=1)(C1C=CC=CC=1)C[C@H]1OC(C)(C)O[C@@H]1CP(C1C=CC=CC=1)C1C=CC=CC=1 |&1:14,20,r|
CAS DataBase Reference: 37002-48-5

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26
WGK Germany: 3
F: 10-23
HS Code: 29319090
Storage Class: 11 - Combustible Solids
Hazard Classifications: Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical

Product number: B1112
Product name: (2S,3S)-(+)-1,4-Bis(diphenylphosphino)-2,3-O-isopropylidene-2,3-butanediol
Purity: >95.0%(GC)(T)
Packaging: 1g
Price: $122
Updated: 2021/12/16

Strem Chemicals

Product number: 15-2960
Product name: (4S,5S)-(+)-4,5-Bis(diphenylphosphinomethyl)-2,2-dimethyl-1,3-dioxolane, 99.5% (S,S)-DIOP
Packaging: 250mg
Price: $57
Updated: 2024/03/01

Strem Chemicals

Product number: 15-2960
Product name: (4S,5S)-(+)-4,5-Bis(diphenylphosphinomethyl)-2,2-dimethyl-1,3-dioxolane, 99.5% (S,S)-DIOP
Packaging: 1g
Price: $139
Updated: 2024/03/01

TRC

Product number: B430488
Product name: (2S,3S)-(+)-1,4-Bis(diphenylphosphino)-2,3-O-isopropylidene-2,3-butanediol
Packaging: 100mg
Price: $75
Updated: 2021/12/16

ChemScene

Product number: CS-W011503
Product name: (S,S)-DIOP
Purity: ≥98.0%
Packaging: 1g
Price: $100
Updated: 2021/12/16

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(+)-DIOP Chemical Properties,Usage,Production

Chemical Properties

white powder

Uses

It is employed as a ligand for the in situ preparation of chiral hydrogenation catalysts. It also finds it application for the in situ preparation of chiral hydrogenation catalysts, ligand for Rh(I)-catalyzed asymmetric hydrogenation of enamides, 1,4-disilylation of α,β-unsaturated ketones, Heck reaction of alkenyl iodides, and hydroformylation of olefins.

Purification Methods

It has been recrystallised from *C6H6/pet ether. After 2 recrystallisations from EtOH, it was pure by TLC on silica gel using Me2CO/hexane as solvent. [Kagan & Dang J Am Chem Soc 94 6429 1972.] Lanthanide shift reagents See in “Aliphatic Compounds”, Chapter 4, europium (III) acetate above and Eu(tmc)3 and Eu(tfc)3 below.

(+)-DIOP Preparation Products And Raw materials

Raw materials

L(+)-Diethyl L-tartrate p-Toluenesulfonic acid Triethyl orthoformate Sodium Methanesulfonyl chloride Tetrahydrofuran Ethyl acetate Lithium Aluminum Hydride Dichloromethane L(+)-Tartaric acid Triphenylphosphine PETROLEUM ETHER Lithium

Preparation Products

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(+)-DIOP Suppliers

Americas 1 Austria 1 Belgium 1 China 89 Europe 1 France 1 Germany 3 India 3 Japan 2 South Korea 1 Switzerland 1 United Kingdom 4 United States 10 Global 118

LaaJoo

Tel: 021-60702684 18516024827
Email: huang.jiayi@sinocompound.com
Country: China
ProdList: 2280
Advantage: 58

Shaoxing Zejun Pharmaceuticals Co.,Ltd

Tel: 0575-82126188 15395856318
Email: nbzjyyservice@zejunpharma.com
Country: China
ProdList: 476
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Beijing HwrkChemical Technology Co., Ltd

Tel: 010-89508211 18501085097
Fax: 010-89508210
Email: sales.bj@hwrkchemical.com
Country: China
ProdList: 9411
Advantage: 55

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44802
Advantage: 61

Shanghai Longsheng chemical Co.,Ltd.

Tel: 021-58099652-8005 13585536065
Fax: 021-58099609
Email: bin.wu@shlschem.com
Country: China
ProdList: 9892
Advantage: 59

Daicel Chiral Technologies (China)CO.,LTD

Tel: 021-50460086-9 15921403865
Fax: +86-21-50462321
Email: han_yajun@dctc.daicel.com
Country: China
ProdList: 7440
Advantage: 65

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View Lastest Price from (+)-DIOP manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: (+)-DIOP 37002-48-5
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 mt
Release date: 2024-12-04

Shaanxi Dideu Medichem Co. Ltd

Product: (2S,3S)-(+)-1,4-Bis(diphenylphosphino)-2,3-O-isopropylidene-2,3-butanediol 37002-48-5
Price: US $1.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 Tons
Release date: 2020-01-14

Career Henan Chemical Co

Product: (+)-DIOP 37002-48-5
Price: US $3.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100kg
Release date: 2019-07-09

37002-48-5, (+)-DIOPRelated Search:

Amino-2-propanol Flexol plasticizer diop (-)-DIOP,(4R,5R)-(-)-4,5-Bis(diphenylphosphinomethyl)-2,2-dimethyl-1,3-dioxolane,99.5%(R,R)-DIOP,(R,R)-DIOP 4-METHYL-1,3-DIOXOLANE 2-METHYL-1,3-DIOXOLANE ETHYLDIPHENYLPHOSPHINE 2,2-DIMETHYL-1,3-DIOXOLANE 1,4-Bis(diphenylphosphino)butane 1,3-Dioxolane 2,2,4-TRIMETHYL-1,3-DIOXOLANE 2,4-DIMETHYL, 1,3-DIOXALONE (+)-DIOP 2,2-Diethoxypropane DIPHENYL-N-PROPYLPHOSPHINE Diphenylphosphine BUTYLDIPHENYLPHOSPHINE 1,4-BIS(DIMETHYLPHOSPHINO)BUTANE (-)-MOD-DIOP

(4S,5S)-(+)-Bis(diphenylphosphinomethyl)-2,2-dimethyl-1,3-dioxolane (+)-DIOP (2S,3S)-(+)-2,3-O-Isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosphino)butane

(+)-2,3-O-Isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosp

(S)-DIOP

(S,S)-4,5-Bis(diphenylphosphinomethyl)-2,2-dimethyl-1,3-dioxolane

1,1'-[[(4S,5S)-2,2-dimethyl-1,3-dioxolane-4,5-diyl]bis(methylene)]bis[1,1-diphenyl-Phosphine

(4S,5S)-(+)-4,5-Bis(diphenylphosphinoMethyl)-2,2-diMethyl-1,3-dioxolane,(S,S)-DIOP.

(+)-4,5-Bis(diphenylphosphinomethyl)-2,2-dimethyl-1,3-dioxolane

(S,S)-2,3-O-isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosphino)butane

[(4S,5S)-5-(diphenylphosphanylmethyl)-2,2- dimethyl-1,3-dioxolan-4-yl]methyl-diphenylphosphane

(4S,5S)-(+)-4,5-Bis(diphenylphosphinomethyl)-2,2- dimethyl-1,3-dioxolane for synthesis

(S,S)-DIOP

(+)-O-ISOPROPYLIDENE-2,3-DIHYDROXY-1,4-BIS(DIPHENYLPHOSPHINO)BUTANE

(+)-1,4-BIS(DIPHENYLPHOSPHINO)-1,4-DIDEOXY-2,3-O-ISOPROPYLIDENE-D-THREITOL

4,5-bis(diphenylphosphinomethyl)-2,2-dimethyl-1,3-dioxalan

(+)-DIOP, (S,S)-DIOP, (4S,5S)-4,5-Bis(diphenylphosphinomethyl)-2,2-dimethyl-1,3-dioxolane, (4S-trans)-[(2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene)]bis(diphenylphosphine)

(4S-TRANS)-[(2,2-DIMETHYL-1,3-DIOXOLANE-4,5-DIYL)BIS(METHYLENE)]BIS(DIPHENYLPHOSPHINE)

(4S,5S)-(+)-4,5-BIS(DIPHENYLPHOSPHINOMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE

(4S,5S)-4,5-BIS(DIPHENYLPHOSPHINO-METHYL)-2,2-DIMETHYL-1,3-DIOXOLANE

(4S 5S)-(+)-O-ISOPROPYLIDENE-2,3-DIHYDROXY-1,4-BIS(DIPHENYLPHOSPHINO)BUTANE

(4S,5S)-(+)-BIS(DIPHENYLPHOSPHINOMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE

(+)-DIOP

(2S,3S)-(+)-1,4-BIS(DIPHENYLPHOSPHINO)-2,3-O-ISOPROPYLIDENE-2,3-BUTANEDIOL

(2S,3S)-(+)-2,3-O-ISOPROPYLIDENE-2,3-DIHYDROXY-1,4-BIS(DIPHENYLPHOSPHINO)BUTANE

(4S,5S)-(+)-4,5-Bis(diphenylphosphinomethyl)-2,2-dimethyl-1,3-dioxolane,99.5%(S,S)-DIOP

Phosphine, (4S,5S)-2,2-dimethyl-1,3-dioxolane-4,5-diylbis(methylene)bisdiphenyl-

(+)-DIOP, (S,S)-DIOP, (+)-1,4-Bis(diphenylphosphino)-1,4-dideoxy-2,3-O-isopropylidene-D-threitol, (4S,5S)-4,5-Bis(diphenylphosphinomethyl)-2,2-dimethyl-1,3-dioxolane, (4S-trans)-[(2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene)]bis(diphenylphosphine)

(4S,5S)-2,2-Dimethyl-4,5-bis(diphenylphosphinomethyl)-1,3-dioxolane

(4α,5β)-2,2-Dimethyl-4,5-bis(diphenylphosphinomethyl)-1,3-dioxolane

[(4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl]bis(methylene)bis(diphenylphosphine)

[(4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl]bismethylenebis(diphenylphosphine)

[[(4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl]bis(methylene)]bis(diphenylphosphine)

(4S,5S)-(+)-4,5-Bis(diphenylphosphinoMethyl)-2,2-diMethyl-1,3-dioxolane,99% (S,S)-DIOP

(+)-2,3-O-Isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosphino)butane,98%

(2S,3S)-(+)-1,4-Bis(diphenylphosphino)-2,3-O-isopropylidene-2,3-butanediol &gt

(2S,3S)-(+)-1,4-Bis(diphenylphosphino)-2,3-O-isopropylidene-2,3-butanediol[(+)-DIOP]

(4S,5S)-(+)-4,5-BIS(DIPHENYLPHOSPHINOMET

Phosphine, 1,1'-[[(4S,5S)-2,2-dimethyl-1,3-dioxolane-4,5-diyl]bis(methylene)]bis[1,1-diphenyl-

(+)-2,3-O-Isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosphino)

(2S,3S)-(+)-1,4-Bis(diphenyL

idene-2,3-butanedioL

phosphino)-2,3-O-isopropyL

(((4S,5S)-2,2-dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphane)

(+)-2,2-dimethyl-4,5-((diphenylphosphino)dimethyl)dioxolane

(+)-2,3-o-Isopropylidene-2,3-Dihydroxy-1,4-Bis(Diphenylphosphino)Butane

(S,S)-DIOP/(4S,5S)-(+)-4,5-Bis(diphenylphosphinomethyl)-2,2-dimethyl-1,3-dioxolane

(4S,5S)-(+)-4,5-Bis(diphenylphosphinomethyl)-2,2-dimethyl-1,3-dioxolane,98% (S,S)-DIOP

1,1'-[[(4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl]bis(methylene)]bis[1,1-diphenylphosphine

(+)-DIOP

37002-48-5

Phosphine Ligands

Dioxanes & Dioxolanes

Asymmetric Synthesis

Dioxolanes

Chiral Catalysts, Ligands, and Reagents

Privileged Ligands

organophosphine ligand

Phosphine Ligands

Asymmetric Synthesis