ChemicalBook > CAS DataBase List > (+)-DIOP

(+)-DIOP

Product Name
(+)-DIOP
CAS No.
37002-48-5
Chemical Name
(+)-DIOP
Synonyms
(S)-DIOP;(+)-DIOP;(+)-DIOP;(S,S)-DIOP;idene-2,3-butanedioL;phosphino)-2,3-O-isopropyL;(2S,3S)-(+)-1,4-Bis(diphenyL;(4S,5S)-(+)-4,5-BIS(DIPHENYLPHOSPHINOMET;4,5-bis(diphenylphosphinomethyl)-2,2-dimethyl-1,3-dioxalan;(+)-2,2-dimethyl-4,5-((diphenylphosphino)dimethyl)dioxolane
CBNumber
CB1393749
Molecular Formula
C31H32O2P2
Formula Weight
498.54
MOL File
37002-48-5.mol
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(+)-DIOP Property

Melting point:
86-88 °C(lit.)
alpha 
+26° (c 2.0, CHCl3)
Boiling point:
590.3±25.0 °C(Predicted)
storage temp. 
Store below +30°C.
form 
Powder
color 
White
Water Solubility 
Sparingly soluble in water at 25°C 2.1E-5 g/L.
Sensitive 
Air Sensitive
BRN 
1630280
InChIKey
VCHDBLPQYJAQSQ-LOYHVIPDSA-N
CAS DataBase Reference
37002-48-5
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26
WGK Germany 
3
F 
10-23
HS Code 
29319090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical
Product number
B1112
Product name
(2S,3S)-(+)-1,4-Bis(diphenylphosphino)-2,3-O-isopropylidene-2,3-butanediol
Purity
>95.0%(GC)(T)
Packaging
1g
Price
$122
Updated
2021/12/16
Alfa Aesar
Product number
B21013
Product name
(+)-DIOP, 98%
Packaging
1g
Price
$108
Updated
2021/12/16
Alfa Aesar
Product number
B21013
Product name
(+)-DIOP, 98%
Packaging
0.25g
Price
$47.2
Updated
2021/12/16
Strem Chemicals
Product number
15-2960
Product name
(4S,5S)-(+)-4,5-Bis(diphenylphosphinomethyl)-2,2-dimethyl-1,3-dioxolane, 99.5% (S,S)-DIOP
Packaging
250mg
Price
$57
Updated
2024/03/01
Strem Chemicals
Product number
15-2960
Product name
(4S,5S)-(+)-4,5-Bis(diphenylphosphinomethyl)-2,2-dimethyl-1,3-dioxolane, 99.5% (S,S)-DIOP
Packaging
1g
Price
$139
Updated
2024/03/01
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(+)-DIOP Chemical Properties,Usage,Production

Chemical Properties

white powder

Uses

It is employed as a ligand for the in situ preparation of chiral hydrogenation catalysts. It also finds it application for the in situ preparation of chiral hydrogenation catalysts, ligand for Rh(I)-catalyzed asymmetric hydrogenation of enamides, 1,4-disilylation of α,β-unsaturated ketones, Heck reaction of alkenyl iodides, and hydroformylation of olefins.

Purification Methods

It has been recrystallised from *C6H6/pet ether. After 2 recrystallisations from EtOH, it was pure by TLC on silica gel using Me2CO/hexane as solvent. [Kagan & Dang J Am Chem Soc 94 6429 1972.] Lanthanide shift reagents See in “Aliphatic Compounds”, Chapter 4, europium (III) acetate above and Eu(tmc)3 and Eu(tfc)3 below.

(+)-DIOP Preparation Products And Raw materials

Raw materials

L(+)-Diethyl L-tartrate p-Toluenesulfonic acid Triethyl orthoformate Sodium Methanesulfonyl chloride Tetrahydrofuran Ethyl acetate Lithium Aluminum Hydride Dichloromethane L(+)-Tartaric acid Triphenylphosphine PETROLEUM ETHER Lithium

Preparation Products

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View Lastest Price from (+)-DIOP manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
(2S,3S)-(+)-1,4-Bis(diphenylphosphino)-2,3-O-isopropylidene-2,3-butanediol 37002-48-5
Price
US $1.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 Tons
Release date
2020-01-14
Hebei Mojin Biotechnology Co., Ltd
Product
(+)-DIOP 37002-48-5
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
5000000kg
Release date
2023-08-15
Hebei Guanlang Biotechnology Co., Ltd.
Product
(+)-DIOP 37002-48-5
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 mt
Release date
2023-01-09

37002-48-5, (+)-DIOPRelated Search:

Amino-2-propanol Flexol plasticizer diop (-)-DIOP,(4R,5R)-(-)-4,5-Bis(diphenylphosphinomethyl)-2,2-dimethyl-1,3-dioxolane,99.5%(R,R)-DIOP,(R,R)-DIOP 4-METHYL-1,3-DIOXOLANE 2-METHYL-1,3-DIOXOLANE ETHYLDIPHENYLPHOSPHINE 2,2-DIMETHYL-1,3-DIOXOLANE 1,4-Bis(diphenylphosphino)butane 1,3-Dioxolane 2,2,4-TRIMETHYL-1,3-DIOXOLANE 2,4-DIMETHYL, 1,3-DIOXALONE (+)-DIOP 2,2-Diethoxypropane DIPHENYL-N-PROPYLPHOSPHINE Diphenylphosphine BUTYLDIPHENYLPHOSPHINE 1,4-BIS(DIMETHYLPHOSPHINO)BUTANE (-)-MOD-DIOP

  • (4S,5S)-(+)-Bis(diphenylphosphinomethyl)-2,2-dimethyl-1,3-dioxolane (+)-DIOP (2S,3S)-(+)-2,3-O-Isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosphino)butane
  • (+)-2,3-O-Isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosp
  • (S)-DIOP
  • (S,S)-4,5-Bis(diphenylphosphinomethyl)-2,2-dimethyl-1,3-dioxolane
  • 1,1'-[[(4S,5S)-2,2-dimethyl-1,3-dioxolane-4,5-diyl]bis(methylene)]bis[1,1-diphenyl-Phosphine
  • (4S,5S)-(+)-4,5-Bis(diphenylphosphinoMethyl)-2,2-diMethyl-1,3-dioxolane,(S,S)-DIOP.
  • (+)-4,5-Bis(diphenylphosphinomethyl)-2,2-dimethyl-1,3-dioxolane
  • (S,S)-2,3-O-isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosphino)butane
  • [(4S,5S)-5-(diphenylphosphanylmethyl)-2,2- dimethyl-1,3-dioxolan-4-yl]methyl-diphenylphosphane
  • (4S,5S)-(+)-4,5-Bis(diphenylphosphinomethyl)-2,2- dimethyl-1,3-dioxolane for synthesis
  • (S,S)-DIOP
  • (+)-O-ISOPROPYLIDENE-2,3-DIHYDROXY-1,4-BIS(DIPHENYLPHOSPHINO)BUTANE
  • (+)-1,4-BIS(DIPHENYLPHOSPHINO)-1,4-DIDEOXY-2,3-O-ISOPROPYLIDENE-D-THREITOL
  • 4,5-bis(diphenylphosphinomethyl)-2,2-dimethyl-1,3-dioxalan
  • (+)-DIOP, (S,S)-DIOP, (4S,5S)-4,5-Bis(diphenylphosphinomethyl)-2,2-dimethyl-1,3-dioxolane, (4S-trans)-[(2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene)]bis(diphenylphosphine)
  • (4S-TRANS)-[(2,2-DIMETHYL-1,3-DIOXOLANE-4,5-DIYL)BIS(METHYLENE)]BIS(DIPHENYLPHOSPHINE)
  • (4S,5S)-(+)-4,5-BIS(DIPHENYLPHOSPHINOMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE
  • (4S,5S)-4,5-BIS(DIPHENYLPHOSPHINO-METHYL)-2,2-DIMETHYL-1,3-DIOXOLANE
  • (4S 5S)-(+)-O-ISOPROPYLIDENE-2,3-DIHYDROXY-1,4-BIS(DIPHENYLPHOSPHINO)BUTANE
  • (4S,5S)-(+)-BIS(DIPHENYLPHOSPHINOMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE
  • (+)-DIOP
  • (2S,3S)-(+)-1,4-BIS(DIPHENYLPHOSPHINO)-2,3-O-ISOPROPYLIDENE-2,3-BUTANEDIOL
  • (2S,3S)-(+)-2,3-O-ISOPROPYLIDENE-2,3-DIHYDROXY-1,4-BIS(DIPHENYLPHOSPHINO)BUTANE
  • (+)-2,3-O-ISOPROPYLIDENE-2,3-DIHYDROXY-1,4-BIS(DIPHENYLPHOSPHINO)BUTANE
  • (4S,5S)-(+)-4,5-Bis(diphenylphosphinomethyl)-2,2-dimethyl-1,3-dioxolane,99.5%(S,S)-DIOP
  • Phosphine, (4S,5S)-2,2-dimethyl-1,3-dioxolane-4,5-diylbis(methylene)bisdiphenyl-
  • (+)-DIOP, (S,S)-DIOP, (+)-1,4-Bis(diphenylphosphino)-1,4-dideoxy-2,3-O-isopropylidene-D-threitol, (4S,5S)-4,5-Bis(diphenylphosphinomethyl)-2,2-dimethyl-1,3-dioxolane, (4S-trans)-[(2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene)]bis(diphenylphosphine)
  • (4S,5S)-2,2-Dimethyl-4,5-bis(diphenylphosphinomethyl)-1,3-dioxolane
  • (4α,5β)-2,2-Dimethyl-4,5-bis(diphenylphosphinomethyl)-1,3-dioxolane
  • [(4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl]bis(methylene)bis(diphenylphosphine)
  • [(4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl]bismethylenebis(diphenylphosphine)
  • [[(4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl]bis(methylene)]bis(diphenylphosphine)
  • (4S,5S)-(+)-4,5-Bis(diphenylphosphinoMethyl)-2,2-diMethyl-1,3-dioxolane,99% (S,S)-DIOP
  • (+)-2,3-O-Isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosphino)butane,98%
  • (2S,3S)-(+)-1,4-Bis(diphenylphosphino)-2,3-O-isopropylidene-2,3-butanediol &gt
  • (2S,3S)-(+)-1,4-Bis(diphenylphosphino)-2,3-O-isopropylidene-2,3-butanediol[(+)-DIOP]
  • (4S,5S)-(+)-4,5-BIS(DIPHENYLPHOSPHINOMET
  • Phosphine, 1,1'-[[(4S,5S)-2,2-dimethyl-1,3-dioxolane-4,5-diyl]bis(methylene)]bis[1,1-diphenyl-
  • (+)-2,3-O-Isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosphino)
  • (2S,3S)-(+)-1,4-Bis(diphenyL
  • idene-2,3-butanedioL
  • phosphino)-2,3-O-isopropyL
  • (((4S,5S)-2,2-dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphane)
  • (+)-2,2-dimethyl-4,5-((diphenylphosphino)dimethyl)dioxolane
  • (+)-2,3-o-Isopropylidene-2,3-Dihydroxy-1,4-Bis(Diphenylphosphino)Butane
  • (+)-DIOP
  • (S,S)-DIOP/(4S,5S)-(+)-4,5-Bis(diphenylphosphinomethyl)-2,2-dimethyl-1,3-dioxolane
  • (+)-2,3-O-Isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosp
  • 37002-48-5
  • Phosphine Ligands
  • Dioxanes & Dioxolanes
  • Asymmetric Synthesis
  • Dioxolanes
  • Chiral Catalysts, Ligands, and Reagents
  • Privileged Ligands
  • organophosphine ligand
  • Phosphine Ligands
  • Asymmetric Synthesis