ChemicalBook > CAS DataBase List > L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID

L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID

Product Name
L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID
CAS No.
42438-90-4
Chemical Name
L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID
Synonyms
TCR;TNCA;L -CarL;H-TPI-OH;H-THNH(3)-OH;Lycoperodine 1;TNCA >=98% (HPLC);RARECHEM BK PT 0088;CYCLOMETHYLTRYPTOPHAN;Tryptophan Impurity M
CBNumber
CB1395455
Molecular Formula
C12H12N2O2
Formula Weight
216.24
MOL File
42438-90-4.mol
More
Less

L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID Property

Melting point:
289 °C (dec.)(lit.)
Boiling point:
485.0±45.0 °C(Predicted)
Density 
1.377±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
soluble1.5mg/mL, clear (Solvent: 0.1N HCl:DMSO (1:1); warmed)
pka
2.28±0.20(Predicted)
form 
powder
color 
white to beige
optical activity
[α]/D -57 to -67°, c = 1 (in MeOH:1N HCl (1:1))
InChIKey
FSNCEEGOMTYXKY-JTQLQIEISA-N
CAS DataBase Reference
42438-90-4(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
HazardClass 
IRRITANT
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P233Keep container tightly closed.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304IF INHALED:

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P340Remove victim to fresh air and keep at rest in a position comfortable for breathing.

P362Take off contaminated clothing and wash before reuse.

P403Store in a well-ventilated place.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML1711
Product name
(S)-(?)-2,3,4,9-Tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid
Purity
≥98% (HPLC)
Packaging
10mg
Price
$56.9
Updated
2024/03/01
Sigma-Aldrich
Product number
SML1711
Product name
(S)-(?)-2,3,4,9-Tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid
Purity
≥98% (HPLC)
Packaging
50mg
Price
$233
Updated
2024/03/01
TRC
Product number
T795458
Product name
L-1,2,3,4-Tetrahydronorharman-3-carboxylicAcid
Packaging
200mg
Price
$160
Updated
2021/12/16
AK Scientific
Product number
Z5873
Product name
(S)-(?)-2,3,4,9-Tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid
Packaging
1g
Price
$77
Updated
2021/12/16
Chem-Impex
Product number
06279
Product name
L-1,2,3,4-Tetrahydronorharman-3-carboxylicacid,98%
Purity
98%
Packaging
5G
Price
$78.4
Updated
2021/12/16
More
Less

L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID Chemical Properties,Usage,Production

Chemical Properties

White to off-white powder

Biochem/physiol Actions

TNCA is a tryptophan derivative that binds the parathyroid Ca2+-sensing receptor (CaSR) extracellular domain (ECD) hinge region between two globular subdomains and acts as a high-affinity CaSR ligand (CaSRL) with co-agonist activity. TNCA is shown to potentiate both Mg++- and Ca++-evoked cellular calcium response (0.1-0.5 mM), as well as Mg++-evoked cellular ERK1/2 phosphorylation in CaSR-expressing HEK293 cells (0.5 mM). AC-265347 (Cat. No. SML0129), on the other hand, is a calcimimetic that functions as a CaSR agonist.

L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID Suppliers

China 69 Germany 5 India 2 Japan 3 Switzerland 1 United Kingdom 1 United States 18 Global 99
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
Shanghai HC Biotech Co., Ltd
Tel
021-20227858
Fax
+86-21-20227857
Email
sale@hcbiotech.com.cn
Country
China
ProdList
1095
Advantage
55
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696;
Email
info@hanhongsci.com
Country
China
ProdList
42982
Advantage
64
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15421
Advantage
60
Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
+8618575662672 18575662672
Fax
021 51613951
Email
mzeng@3wpharm.com
Country
China
ProdList
9748
Advantage
57
Shenzhen Sungening Bio-Tech Co., Ltd
Tel
+86-0755-89668383
Fax
+86-0755-89594066/4038
Email
sales@sungening.com
Country
China
ProdList
1319
Advantage
65
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12338
Advantage
58
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18216
Advantage
56
Amatek Scientific Co. Ltd.
Tel
0512-56316828 4008675858
Fax
+86-512-56316826
Email
sales@amateksci.com
Country
China
ProdList
9908
Advantage
55
Bide Pharmatech Ltd.
Tel
400-1647117 15221909166
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41438
Advantage
60
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
17982
Advantage
56
Sichuan Wei Keqi Biological Technology Co., Ltd.
Tel
028-81700200 18116577057
Fax
028-81705658
Email
3003855609@qq.com
Country
China
ProdList
7892
Advantage
56
Shanghai Kewel Chemical Co., Ltd.
Tel
021-64609169 18901607656
Fax
021-64609160
Email
greensnown@163.com
Country
China
ProdList
9911
Advantage
50
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51471
Advantage
80
Shenzhen Chim Biotech Co., Ltd.
Tel
0755-36320761 13692196024
Fax
0755-28364769
Email
sales@chimchem.com
Country
China
ProdList
501
Advantage
55
Shanghai GL Peptide Ltd.
Tel
+86-21-61263310; 13764994101 13764994101
Fax
021-61263399
Email
fisherwang@glschina.com
Country
China
ProdList
8457
Advantage
55
Wuxi Asia Peptide Biotechnology Limited Company
Tel
0510-83583050 13771062561
Fax
0510-83583039
Email
willsun@peptide-search.com
Country
China
ProdList
6716
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131981
Advantage
58
Nanjing Peptide Biotech Ltd.
Tel
025-58361106-805 13082558573
Fax
025-58361106-806
Email
liugang@njpeptide.com
Country
China
ProdList
9961
Advantage
55
Shandong Ono Chemical Co., Ltd.
Tel
0539-6362799 20）
Fax
0539-6362799（To 20）
Country
China
ProdList
10007
Advantage
58
Aikon International Limited
Tel
025-66113011 18112977050
Fax
(5)02557626880
Email
cb6@aikonchem.com
Country
China
ProdList
15495
Advantage
58
Henan Aosman Biotechnology Co., LTD
Tel
0371-61318675 17719817155
Fax
0371-61318675
Email
2366079749@qq.com
Country
China
ProdList
871
Advantage
58
3A Chemicals
Tel
400-668-9898
Fax
010-51582189
Email
service@3achem.com
Country
China
ProdList
20569
Advantage
58
Shanghai Jifeng Biotechnology Co., Ltd.
Tel
021-61263377 15023907684
Fax
021-61263399
Email
15800684150@163.com
Country
China
ProdList
8131
Advantage
58
Nextpeptide Inc
Tel
+86-0571-81612335 +8613336028439
Email
sales@nextpeptide.com
Country
China
ProdList
19915
Advantage
58
AFINE CHEMICALS LIMITED
Tel
0571-85134551
Fax
008657185134895
Email
info@afinechem.com
Country
CHINA
ProdList
15377
Advantage
58
GL Biochem(Binhai) Ltd.
Tel
+86-021-61263370 +8615301650015
Email
wuqiuyan@glschina.com
Country
China
ProdList
2975
Advantage
58
Henan Weituxi Chemical Technology Co., Ltd.
Tel
0371-63284658; 18135795563
Fax
QQ:2885349392
Email
2885349392@qq.com
Country
China
ProdList
9997
Advantage
58
Shanghai Anhua Biotechnology Co., Ltd.
Tel
021-61263375 18168859245
Country
China
ProdList
5958
Advantage
58
Wuxi maimo topp biotechnology co., LTD
Tel
13771048682
Email
alice@mimotopes.cn
Country
China
ProdList
5854
Advantage
58
Qi Qi hang Biotechnology Co., Ltd.
Tel
13291169750 18151111370
Email
1046215251@qq.com
Country
China
ProdList
7988
Advantage
58
Jiangsu Jitai Peptide Technology Co., Ltd.
Tel
18762539991 17851618148
Email
sales04@gtaipeptide.com
Country
China
ProdList
2008
Advantage
58
Jiangsu Shengkang Meixiang Technology Co., Ltd.
Tel
18217475093
Email
1615396342@qq.com
Country
China
ProdList
4309
Advantage
58
Jiangsu yize medical technology co. LTD
Tel
18550739526
Email
3394205705@qq.com
Country
China
ProdList
9409
Advantage
58
Changzhou Kechem Bio-Scientific Co., LTD.
Tel
0519-68985668 13685222090
Fax
qq735434464
Email
sales@kechem.cn
Country
China
ProdList
26033
Advantage
58
Shanghai Hewu Biotechnology Co., LTD
Tel
021-57886085 17317861055
Email
shhebio@126.com
Country
CHINA
ProdList
7975
Advantage
58
SANBEM Biotech (Suzhou) Co., Ltd.
Tel
0512-85667806 18551283436
Fax
0512-85667816
Email
sales@sanbem.com
Country
China
ProdList
3018
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing@energy-chemical.com
Country
China
ProdList
44941
Advantage
58
ChengDu SinoStandards Bio-Tech Co.,Ltd. ，
Tel
028-83243028 19136088901
Email
sinostandards@163.com
Country
China
ProdList
5044
Advantage
58
TCI (Shanghai) Chemical Trading Co., Ltd.
Tel
021-61109150
Fax
021-61105897
Email
sales@tcisct.com
Country
China
ProdList
31163
Advantage
58
Wuhan rheniuhui Biotechnology Co., Ltd
Tel
18062115889
Fax
qq405368533
Email
405368533@qq.com
Country
China
ProdList
166
Advantage
58
Foshan Treasure Biotechnology Co., Ltd
Tel
0757-85921206 18520245316
Email
2329783215@qq.com
Country
China
ProdList
12664
Advantage
58
Changzhou Xianglong Pharmaceutical Technology Co., LTD
Tel
18661161657
Email
yaoxiangqiu2021@163.com
Country
China
ProdList
10066
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 4008210725
Email
malulu@leyan.com
Country
China
ProdList
39997
Advantage
58
Shanghai Yaji Biological Technology Co., Ltd.
Tel
021-34661275 15301693058
Email
yajikit@163.com
Country
China
ProdList
6633
Advantage
58
Shangqiu Ladybug Network Technology Co., LTD
Tel
0370-2059268 15672839268
Fax
03702782809
Email
2352713635@qq.com
Country
China
ProdList
4206
Advantage
58
Bide Pharmatech Ltd.
Tel
400-6005915
Email
sales@picasso-e.com
Country
China
ProdList
39661
Advantage
58
Bejing Famous Pharmaceutical Technology Co., Ltd.
Tel
13331045123
Email
sales@peking-pharmacy.com
Country
China
ProdList
9991
Advantage
58
Hubei Weideli Chemical Reagent Co.，Ltd.
Tel
13339985473
Email
C13339985473@163.com
Country
China
ProdList
3462
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24131
Advantage
58

42438-90-4, L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACIDRelated Search:

BOC-D-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID FMOC-D-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID 1,2,3,4-TETRAHYDRO-9H-PYRIDO[3,4-B]INDOLE (S)-1,2,3,4-Tetrahydronorharman-3-carboxylic acid, N2-FMOC protected,FMOC-L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID BOC-L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID (1S,3S)-2,3,4,9-TETRAHYDRO-1-METHYL-1H-PYRIDO[3,4-B]INDOLE-3-CARBOXYLIC ACID (1S,3S)-1-ETHYL-2,3,4,9-TETRAHYDRO-1H-PYRIDO[3,4-B]INDOLE-3-CARBOXYLIC ACID BOC-TPI(FOR)-OH L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID FMOC-DL-6-METHOXY-1,2,3,4-TETRAHYDRONORHARMAN-1-CARBOXYLIC ACID BOC-DL-6-METHOXY-1,2,3,4-TETRAHYDRONORHARMAN-1-CARBOXYLIC ACID D-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID CIS-1-(1,3-BENZODIOXOL-5-YL)-2-(CHLOROACETYL)-2,3,4,9-TETRAHYDRO-, 1H-PYRIDO[3,4-B]INDOLE-3-CARBOXYLIC ACID METHYL ESTER 9-FORMYL-1,2,3,4-TETRAHYDRONORHARMAN-L-3-CARBOXYLIC ACID HYDROCHLORIDE 1,3,4,9-TETRAHYDRO-B-CARBOLINE-2-CARBOXYLIC ACID METHYL ESTER HCL L-1,2,3,4-TETRAHYDRONORHARMANE-3-CARBOXYLIC ACID ETHYL ESTER HYDROCHLORIDE N-ALPHA-CARBOBENZOXY-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID H-TPI-OME

  • L-TRYPTOLINE-3-CARBOXYLIC ACID
  • H-TPI-OH
  • H-THNH(3)-OH
  • L-2,3,4-TETRAHYDRO-BETA-CARBOLINE-3-CARBOXYLIC ACID
  • L-1,2,3,4-TETRAHYDRO-9H-PYRIDO[3,4-B]INDOLE-3-CARBOXYLIC ACID
  • L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID
  • 1,2,3,4-TETRAHYDRONORHARMAN-L-3-CARBOXYLIC ACID
  • RARECHEM BK PT 0088
  • (S)-2,3,4,9-TETRAHYDRO-1H-PYRIDO[3,4-B]INDOLE-3-CARBOXYLIC ACID
  • L-1,2,3,4-tetrahydronorharmane-3-carboxylic acid
  • L-1,2,3,4-Tetrahydro-9H-pyrido[3,4-b]indole-3-carb
  • 2,3,4,9-Tetrahydro-1H-β-carboline-3-carboxylic acid
  • (3S)-1,2,3,4-Tetrahydro-9H-pyrido[3,4-b]indole-3-carboxylic acid
  • (3S)-1,2,3,4-Tetrahydro-β-carboline-3α-carboxylic acid
  • (3S)-2,3,4,9-Tetrahydro-1H-pyrido[3,4-b]indole-3α-carboxylic acid
  • (S)-1,2,3,4-Tetrahydro-β-carboline-3-carboxylic acid
  • (3S)-1H,2H,3H,4H,9H-pyrido[3,4-b]indole-3-carboxylic acid
  • TNCA
  • 4-b]indole-3-carboxylic acid
  • 4-Tetrahydro-9H-pyrido[3
  • 4-Tetrahydro-b-carboline-3-carboxylic acid
  • 9-Tetrahydro-1H-beta-carboline-3-carboxylic acid
  • L -CarL
  • Lycoperodine 1
  • (3S)-2,3,4,9-Tetrahydro-1H-beta-carboline-3-carboxylic acid
  • L-1,2,3,4-Tetrahydro-9H-pyrido[3,4-b]indole-3-carboxylic acid, L-Tryptoline-3-carboxylic acid, H-Tpi-OH, L-1,2,3,4-Tetrahydro-b-carboline-3-carboxylic acid
  • (3S)-1,3,4,9-tetrahydro-$b-carbolin-2-ium-3-carboxylate
  • (3S)-1,3,4,9-tetrahydropyrido[5,4-b]indol-2-ium-3-carboxylate
  • (3S)-2,3,4,9-tetrahydro-1H-$b-carboline-3-carboxylic acid
  • (3S)-2,3,4,9-tetrahydro-1H-pyrido[5,4-b]indole-3-carboxylic acid
  • CYCLOMETHYLTRYPTOPHAN
  • TCR
  • (S)-1,2,3,4-Tetrahydronorharmane-3-carboxylic acid
  • 1H-Pyrido[3,4-b]indole-3-carboxylic acid, 2,3,4,9-tetrahydro-, (3S)-
  • L-1,2,3,4-Tetrahydro-β-carbolin-3-carboxylic acid
  • TNCA >=98% (HPLC)
  • Tryptophan Impurity M
  • 42438-90-4
  • 2438-90-4
  • C12H12NO2
  • Phenylalanine analogs and other aromatic alpha amino acids