Paeoniflorin

Product Name: Paeoniflorin
CAS No.: 23180-57-6
Chemical Name: Paeoniflorin
Synonyms: PACLITAXEL;peoniflorin;Paeoniflorin RS;eoniflorin;NSC 178886;Paeoniflorm;Delmacinone;Paeony root;PAEONIFLORIN;Paeoniflorin
CBNumber: CB1395723
Molecular Formula: C23H28O11
Formula Weight: 480.47
MOL File: 23180-57-6.mol

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Paeoniflorin Property

Melting point:: approximate 124℃ (dec.)
Boiling point:: 498.51°C (rough estimate)
Density: 1.3044 (rough estimate)
refractive index: 1.5376 (estimate)
storage temp.: 2-8°C
solubility: Methanol (Slightly, Sonicated), Pyridine (Slightly)
pka: 11.52±0.70(Predicted)
form: powder
color: white
biological source: plant (Paeonia Albiflora)
Water Solubility: water: insoluble
Major Application: food and beverages
Cosmetics Ingredients Functions: SKIN PROTECTING
InChIKey: YKRGDOXKVOZESV-WRJNSLSBSA-N
SMILES: C[C@@]12C[C@@]3(O)O[C@@H](O1)[C@]5(COC(=O)c4ccccc4)[C@H]3C[C@]25O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O
CAS DataBase Reference: 23180-57-6(CAS DataBase Reference)

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Safety

Safety Statements: 24/25
WGK Germany: 3
RTECS: RT1200000
HS Code: 29389090
Storage Class: 11 - Combustible Solids
Toxicity: LD50 ipr-mus: 9530 mg/kg YKKZAJ 89,879,69

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H226Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: P0038
Product name: Paeoniflorin
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $279
Updated: 2026/03/19

Sigma-Aldrich

Product number: 75603
Product name: Paeoniflorin
Purity: analytical standard
Packaging: 10mg
Price: $244
Updated: 2026/03/19

TCI Chemical

Product number: P1876
Product name: Paeoniflorin
Purity: >97.0%(HPLC)
Packaging: 100mg
Price: $56
Updated: 2026/03/19

Cayman Chemical

Product number: 19861
Product name: Paeoniflorin
Purity: ≥98%
Packaging: 50mg
Price: $68
Updated: 2024/03/01

Cayman Chemical

Product number: 19861
Product name: Paeoniflorin
Purity: ≥98%
Packaging: 100mg
Price: $121
Updated: 2024/03/01

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Paeoniflorin Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

Paeoniflorin is a herbal constituent extracted from the root of Paeonia albiflora Pall. Paeoniflorin has broad pharmacological effects, such as analgesic, anti-diuretic，anti-inflammatory，anti-convulsant, vasodilatic, and etc. In a study, paeoniflorin effe

Uses

Paeoniflorin is an active compound of the Paeonia root. Paeoniflorin inhibits Aβ25-35-induced mitochondrial dysfunction, which includes decreased mitochondrial membrane potential, increased Bax/Bcl-2 ratio, cytochrome c release and activity of caspase-3 and caspase-9. Paeoniflorin could attenuate or restore the viability loss, apoptotic increase, and ROS production induced by Aβ25-35 in SH-SY5Y cells.

Uses

antiinflammatory, antispasmodic, antihypertensive, antidiuretic

Definition

ChEBI: Paeoniflorin is a terpene glycoside.

General Description

Paeoniflorin has been demonstrated to exert anti-inflammatory and immunomodulatory effects.

Biochem/physiol Actions

Herbal constituent of peony root. It is used in Chinese traditional medicine for its spasmolytic and pain-relieving properties. Exhibits anticoagulant, neuromuscular blocking, cognition-enhancing, immunoregulating, and antihyperglycemic effects.

Safety Profile

Moderately toxic by intravenous route. Mildly toxic by intraperitoneal route. When heated to decomposition it emits acrid smoke and irritating fumes.

Synthesis

Weigh 40kg white peony herbs, soaked in 70% ethanol overnight, reflux extraction 2 times, each time 2h, filtration, combined filtrate, rotary evaporation until no alcohol flavor, adjust the liquid so that each 1ml of liquid is equivalent to 0.5g of raw drug, standby. Weigh 120kg (wet weight) LX38 resin, loaded into a stainless steel column (300 2300cm), column volume of 60L, on the sample, adsorption of 1h, the first 300L of water, 10% ethanol 300L to remove impurities, and then 50% ethanol 360L elution of paeoniflorin and paeonia lactiflora paeoniflora glycosides, and finally 95% ethanol regeneration of resin, the flow rate of 150-200L/h, the 50% ethanol elution of peoniflorin and paeoniflorin. Finally, the resin was regenerated with 95% ethanol at a flow rate of 150-200L/h, and the 50% ethanol was concentrated and evaporated to obtain 2.52kg, in which the purity of paeoniflorin was 24% and that of paeoniflorin was 16%.

Paeoniflorin Preparation Products And Raw materials

Raw materials

Preparation Products

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Paeoniflorin Suppliers

Americas 1 China 522 Czech Republic 1 Europe 2 Germany 2 India 3 Japan 3 Poland 1 Switzerland 1 United Kingdom 8 United States 46 USA 1 Global 591

Nanjing bingcheng Biotechnology Co., Ltd.

Tel: 18805194892
Email: 2727751293@qq.com
Country: China
ProdList: 172
Advantage: 58

Nanjing Yuanzhi Biotechnology Co. Ltd.

Tel: 15805159960
Email: 1211550495@qq.com
Country: China
ProdList: 1797
Advantage: 58

Shaanxi xintianyu Biotechnology Co., Ltd.

Tel: 17749282610; 17749282610
Fax: 029-32562222
Email: 3002817800@qq.com
Country: China
ProdList: 979
Advantage: 58

Nanjing Shangshu Biotechnology Co., Ltd

Tel: 18266960953
Email: 907697096@qq.com
Country: China
ProdList: 3033
Advantage: 58

Shaanxi xinyanghe Biotechnology Co., Ltd

Tel: 18391023245
Email: 1138024985@qq.com
Country: China
ProdList: 827
Advantage: 58

Sichuan Hongen Plant Technology Co., Ltd.

Tel: 18160195668
Fax: 86-838-2803556
Email: 2370026295@qq.com
Country: China
ProdList: 38
Advantage: 58

Nantong Feiyu Biological Technology CO.,LTD

Tel: 0513-68819626; 15152877458
Fax: 0513-68669626
Email: feiyubio@163.com
Country: China
ProdList: 4817
Advantage: 58

Chengdu Push Bio-Technology Co., Ltd.

Tel: 028-85370565-229 18080489829
Email: 18080489829@163.com
Country: China
ProdList: 7974
Advantage: 60

Shaanxi Haochen Biotechnology Co., Ltd

Tel: 18710685966 18710685966
Email: 511325867@qq.com
Country: China
ProdList: 319
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

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View Lastest Price from Paeoniflorin manufacturers

Lianyungang Kaiyu Environmental Tech Co., Ltd.

Product: Paeoniflorin 23180-57-6
Price: US $1200.00-1100.00/ton
Min. Order: 1ton
Purity: 99%
Supply Ability: 1000T/M
Release date: 2025-10-16

Jinan Ruitong Biotech Co., Ltd.

Product: Paeoniflorin 23180-57-6
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1
Release date: 2025-08-21

Wuhan JiyunZen Tech Co., Ltd.

Product: Paeoniflorin 23180-57-6
Price: US $5.00-0.50/KG
Min. Order: 1KG
Purity: 99% hplc
Supply Ability: 500TONS
Release date: 2025-05-08

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PAEONIFLORIN

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Paeoniflorin 23180-57-6

eoniflorin

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beta.-d-Glucopyranoside, 5b-[(benzoyloxy)methyl]tetrahydro-5-hydroxy-2-methyl-2,5-methano-1H-3,4-dioxacyclobuta[cd]pentalen-1a(2H)-yl, [1aR-(1a.alpha.,2.beta.,3a.alpha.,5.alpha.,5a.alpha.,5b.alpha.)]

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Paeoniflorin P.E.

(1aR,2S,3aR,5R,5aR,5bS)-5b-[(benzoyloxy)methyl]tetrahydro-5-hydroxy-2-methyl-2,5-methano-1H-3,4-dioxacyclobuta[cd]pentalen-1a(2H)-yl-β-D-glucopyranoside

Paeoniflorin Extract

NSC 178886

White Paeony Root Extract

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beta-d-glucopyranoside,5b-((benzoyloxy)methyl)tetrahydro-5-hydroxy-2-methyl-2,

beta-d-Glucopyranoside, 5b-[(benzoyloxy)methyl]tetrahydro-5-hydroxy-2-methyl-2,5-methano-1H-3,4-dioxacyclobuta[cd]pentalen-1a(2H)-yl, [1aR-(1aalpha,2beta,3aalpha,5alpha,5aalpha,5balpha)]-

PAEONIFLORIN 98+% BY HPLC

Paeoniflorin std.

PAEONIFLORIN(P)

3aα,5α, 5aα,5bα)]-

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Methylprednisolone Acetate, Micronized

Levofloxacin DMF (under registration)

Delmacinone

Ramipril (DMF, under registration)

Ranitidine (DMF, under registration)

(2R,6aβ)-3aβ-(Benzoyloxymethyl)-4-(β-D-glucopyranosyloxy)-5-methyl-2α,5α:3α,4α-dimethanohexahydrofuro[2,3-b]furan-2-ol

[(1aR)-5bβ-[(Benzoyloxy)methyl]-3aβ,5,5aβ,5b-tetrahydro-5β-hydroxy-2-methyl-2α,5α-methano-3,4-dioxa-1H-cyclobuta[cd]pentalen-1aβ(2H)-yl]β-D-glucopyranoside

[(1aR)-5bβ-[(Benzoyloxy)methyl]-3aβ,5,5aβ,5b-tetrahydro-5β-hydroxy-2β-methyl-2,5-methano-3,4-dioxa-1H-cyclobuta[cd]pentalen-1a(2H)-yl]β-D-glucopyranoside

Paeonia moutan

Paeony root

Paeoniflorin 10%-98%

Paeoniflorin RS

β-D-Glucopyranoside, (1aR,2S,3aR,5R,5aR,5bS)-5b-[(benzoyloxy)methyl]tetrahydro-5-hydroxy-2-methyl-2,5-methano-1H-3,4-dioxacyclobuta[cd]pentalen-1a(2H)-yl

β-d-Glucopyranoside, 5b-[(benzoyloxy)methyl]tetrahydro-5-hydroxy-2-methyl-2,5-methano-1H-3,4-dioxacyclobuta[cd]pentalen-1a(2H)-yl, [1aR-(1aα,2β,3aα,5α,5aα,5bα)]-

Paeoniflorin USP/EP/BP

Paeoniflorin (>80%)

Natural Radix Paeonia Alba Extract 98% Paeoniflorin Powder CAS?23180-57-6

((2S,2aR,2a1S,3aR,4R,5aR)-4-Hydroxy-2-methyl-2a-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexahydro-2H-1,5-dioxa-2,4-methanocyclobuta[cd]pentalen-2a1-yl)methyl benzoate

b-D-Glucopyranoside,(1aR,2S,3aR,5R,5aR,5bS)-5b-[(benzoyloxy)methyl]tetrahydro-5-hydroxy-2-methyl-2,5-methano-1H-3,4-dioxacyclobuta[cd]pentalen-1a(2H)-yl

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Abmole M3941-200mg Paeoniflorin 23180-57-6

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