3-(TRIMETHYLSILYL)PROPIOLIC ACID
- Product Name
- 3-(TRIMETHYLSILYL)PROPIOLIC ACID
- CAS No.
- 5683-31-8
- Chemical Name
- 3-(TRIMETHYLSILYL)PROPIOLIC ACID
- Synonyms
- DKFELEX0274;3-(Trimethylsi;TIMTEC-BB SBB009048;Trimethylsilanyl-propynoic acid;3-(TRIMETHYLSILYL)PROPYNOIC ACID;3-(TRIMETHYLSILYL)PROPIOLIC ACID;3-trimethylsilyl-2-propynoic acid;3-(Trimethylsilyl)propargylic Acid;3-(trimethylsilyl)prop-2-ynoic acid;3-(Trimethylsilyl)propynoic acid 98%
- CBNumber
- CB1397217
- Molecular Formula
- C6H10O2Si
- Formula Weight
- 142.23
- MOL File
- 5683-31-8.mol
3-(TRIMETHYLSILYL)PROPIOLIC ACID Property
- Melting point:
- 47-49 °C (lit.)
- Boiling point:
- 105-110 °C/10 mmHg (lit.)
- Density
- 1.006±0.06 g/cm3(Predicted)
- Flash point:
- 205 °F
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- Soluble in methanol.
- form
- solid
- pka
- 1.88±0.10(Predicted)
- color
- White to Almost white
- Hydrolytic Sensitivity
- 4: no reaction with water under neutral conditions
- BRN
- 1755674
- InChI
- InChI=1S/C6H10O2Si/c1-9(2,3)5-4-6(7)8/h1-3H3,(H,7,8)
- InChIKey
- IPEATTYBFBRNEB-UHFFFAOYSA-N
- SMILES
- C(O)(=O)C#C[Si](C)(C)C
- CAS DataBase Reference
- 5683-31-8(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 403482
- Product name
- 3-(Trimethylsilyl)propynoic acid
- Purity
- 98%
- Packaging
- 1g
- Price
- $73.4
- Updated
- 2025/07/31
- Product number
- 403482
- Product name
- 3-(Trimethylsilyl)propynoic acid
- Purity
- 98%
- Packaging
- 5g
- Price
- $215
- Updated
- 2025/07/31
- Product number
- T3040
- Product name
- 3-(Trimethylsilyl)propiolic Acid
- Purity
- >97.0%(GC)(T)
- Packaging
- 1g
- Price
- $374
- Updated
- 2025/07/31
- Product number
- T3040
- Product name
- 3-(Trimethylsilyl)propiolic Acid
- Purity
- >97.0%(GC)(T)
- Packaging
- 5g
- Price
- $1495
- Updated
- 2025/07/31
- Product number
- JK940187
- Product name
- 3-(Trimethylsilyl)propiolic Acid
- Purity
- 97%
- Packaging
- 1g
- Price
- $58
- Updated
- 2021/12/16
3-(TRIMETHYLSILYL)PROPIOLIC ACID Chemical Properties,Usage,Production
Uses
3-(Trimethylsilyl)propiolic acid may be used in the regioselective preparation of 1,5-trisubstituted 1H-1,2,3-triazoles. It is also used as pharmaceutical intermediate.
Synthesis
2975-46-4
5683-31-8
The general procedure for the synthesis of 3-(trimethylsilyl)propynoic acid from 3-trimethylsilylpropynal was as follows: in a reaction test tube, trans-2-decene (167 mg, 1.0 mmol) was added to a mixture containing Fe(NO3)3-9H2O (4.1 mg, 0.010 mmol) and CF3COONa (28 mg, 0.20 mmol) in an EtOAc (0.50 mL) in suspension. An O2 balloon (1 atm) was attached to the top of the test tube to displace the internal atmosphere with O2. After the reaction mixture was stirred at 25 °C for 16 h, EtOAc (3 mL) and 1 M HCl aqueous solution (1 mL) were added and the resulting two-phase mixture was stirred for 1 min. The organic phase was separated and the aqueous phase was extracted with EtOAc (3 mL × 2). After combining the organic phases, quantitative biphenyl (as an internal standard for NMR analysis) was added. The conversion of the substrate and the yield of the product were determined by NMR analysis (400 MHz, CDCl3, 25 °C). Products were identified by comparing the NMR signals of real samples. Each reaction was repeated twice to ensure reproducible results.
References
[1] Chemistry Letters, 2016, vol. 45, # 2, p. 188 - 190
3-(TRIMETHYLSILYL)PROPIOLIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
3-(TRIMETHYLSILYL)PROPIOLIC ACID Suppliers
- Tel
- --
- Fax
- --
- sales@chemos-group.com
- Country
- Germany
- ProdList
- 6350
- Advantage
- 71
- Tel
- --
- Fax
- --
- info@abcr.de
- Country
- Germany
- ProdList
- 6831
- Advantage
- 75
View Lastest Price from 3-(TRIMETHYLSILYL)PROPIOLIC ACID manufacturers
- Product
- 3-(TRIMETHYLSILYL)PROPIOLIC ACID 5683-31-8
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 mt
- Release date
- 2024-12-04
- Product
- 3-(TRIMETHYLSILYL)PROPIOLIC ACID 5683-31-8
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 95%-99%
- Supply Ability
- as request
- Release date
- 2018-12-24