3-TRIMETHYLSILYLPROPYNAL

Product Name: 3-TRIMETHYLSILYLPROPYNAL
CAS No.: 2975-46-4
Chemical Name: 3-TRIMETHYLSILYLPROPYNAL
Synonyms: 3-(triMethylsilyl)propiolaldehyde;DK722;DKFELEX0187;)-2-propynaL;Trimethylsilylpropynal;3-TRIMETHYLSILYLPROPYNAL;3-Trimethylsilylpropynol;(Trimethylsilyl)propynal;Trimethylsilanyl-propynal;3-Trimethylsilylprop-2-Ynal
CBNumber: CB4288965
Molecular Formula: C6H10OSi
Formula Weight: 126.23
MOL File: 2975-46-4.mol

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3-TRIMETHYLSILYLPROPYNAL Property

Melting point:: 195 °C
Boiling point:: 52 °C
Density: 0.854 g/mL at 25 °C
refractive index: n20/D 1.444
Flash point:: >25°C
storage temp.: 2-8°C
form: Liquid
Specific Gravity: 0.86
color: Colorless to yellow
Sensitive: Air & Moisture Sensitive
Hydrolytic Sensitivity: 4: no reaction with water under neutral conditions
InChI: InChI=1S/C6H10OSi/c1-8(2,3)6-4-5-7/h5H,1-3H3
InChIKey: LJRWLSKYGWLYIM-UHFFFAOYSA-N
SMILES: C(=O)C#C[Si](C)(C)C

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Safety

Hazard Codes: Xi
Risk Statements: 10-36/37/38
Safety Statements: 16-36/37/39-36/37-26
RIDADR: 1993
WGK Germany: 3
TSCA: No
HazardClass: 3
PackingGroup: II
HS Code: 29319090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H226Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 687170
Product name: 3-(Trimethylsilyl)-2-propynal
Purity: 97%
Packaging: 1g
Price: $40
Updated: 2023/06/20

TCI Chemical

Product number: T2907
Product name: 3-Trimethylsilylpropynal
Purity: >97.0%(GC)
Packaging: 1g
Price: $179
Updated: 2025/07/31

TCI Chemical

Product number: T2907
Product name: 3-Trimethylsilylpropynal
Purity: >97.0%(GC)
Packaging: 5g
Price: $533
Updated: 2025/07/31

TRC

Product number: T896568
Product name: 3-(Trimethylsilyl)-2-propynal
Packaging: 500mg
Price: $60
Updated: 2021/12/16

Frontier Specialty Chemicals

Product number: JK345372
Product name: 3-Trimethylsilylpropynal
Packaging: 1g
Price: $113
Updated: 2021/12/16

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3-TRIMETHYLSILYLPROPYNAL Chemical Properties,Usage,Production

Uses

3-Trimethylsilylpropynal acts as an important organic intermediate. It is used in agrochemicals, pharmaceuticals and dyestuff field. Further, it is used in the preparation of [3-(trimethylsilyl)-2-propinyliden]-malononitrile.

Synthesis

68-12-2

1066-54-2

2975-46-4

Steps for the synthesis of 3-trimethylsilylpropynal: 1. A solution of trimethylsilylacetylene (5.0 mL, 36.10 mmol) in THF (25.0 mL) was added dropwise to a solution of EtMgBr in THF (1 M, 44.0 mL, 44.0 mmol) under nitrogen protection, and the reaction temperature was maintained at 10-150°C. 2. After the dropwise addition, the reaction mixture was stirred at room temperature for 1 hour. 3. A solution of Et2O (20.0 mL) in DMF (10.0 mL, 123.0 mmol) was slowly added to the reaction system at -25 °C, and the addition time was controlled to be within 30 min. 4. The resulting white suspension was gradually warmed to room temperature and stirring was continued for 1 hour. 5. The reaction mixture was heated to 30 °C and maintained for 15 minutes. 6. The reaction solution was cooled to 0 °C and poured into 5% H2SO4 solution. 7. The aqueous layer was separated and extracted three times with Et2O. 8. Combine the organic layers, wash with saturated aqueous NH4Cl solution and dry with anhydrous Na2SO4. 9. Concentrate under pressure to remove the solvent and obtain the crude product. 10. purification of the crude product by ball-to-ball distillation (20 mbar, room temperature) afforded 3-trimethylsilylpropynal (2.255 g, 49% yield). Product characterization data: 1H NMR: δ 9.15 (s, 1H), 0.25 (s, 9H). 13C NMR: δ 176.7, 103.0, 102.3, 0.88.

References

[1] Tetrahedron Letters, 1995, vol. 36, # 3, p. 401 - 404
[2] Angewandte Chemie - International Edition, 2008, vol. 47, # 6, p. 1130 - 1133
[3] Tetrahedron, 2002, vol. 58, # 12, p. 2415 - 2422
[4] Arkivoc, 2012, vol. 2012, # 7, p. 253 - 273
[5] Patent: WO2009/141781, 2009, A1. Location in patent: Page/Page column 18

3-TRIMETHYLSILYLPROPYNAL Preparation Products And Raw materials

Raw materials

Preparation Products

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3-TRIMETHYLSILYLPROPYNAL Suppliers

China 142 Germany 1 India 1 Japan 1 Singapore 1 Slovakia 1 Switzerland 1 United Kingdom 2 United States 16 Global 166

Shanghai Guijing New Material Technology Co., Ltd.

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J & K SCIENTIFIC LTD.

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Alfa Aesar

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TCI (Shanghai) Development Co., Ltd.

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Energy Chemical

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Jia Xing Isenchem Co.,Ltd

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Shanghai Hanhong Scientific Co.,Ltd.

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China DongFan Chemical Co.,LTD

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View Lastest Price from 3-TRIMETHYLSILYLPROPYNAL manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 3-TRIMETHYLSILYLPROPYNAL 2975-46-4
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 mt
Release date: 2025-03-07

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: 3-TRIMETHYLSILYLPROPYNAL 2975-46-4
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20ton
Release date: 2024-06-05

Career Henan Chemical Co

Product: 3-TRIMETHYLSILYLPROPYNAL 2975-46-4
Price: US $2.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: customsie
Release date: 2018-08-20

2975-46-4, 3-TRIMETHYLSILYLPROPYNALRelated Search:

(TERT-BUTYLDIMETHYLSILYLOXY)ACETALDEHYDE Propyne 3-(TRIMETHYLSILYL)PROPIOLIC ACID METHYL 3-(TRIMETHYLSILYL)PROPIOLATE 4-(Trimethylsilyl)-3-butyn-2-one 3-TRIMETHYLSILYLPROPYNAL 1-CHLORO-4-TRIMETHYLSILANYL-BUT-3-YN-2-ONE ETHYL 3-(TRIMETHYLSILYL)PROPIOLATE TRIMETHYLSILYL(TRIMETHYLSILYL)PROPYNOATE 3-(Triethylsilyl)-2-propynal PROPYNAL 1-PHENYL-4-TRIMETHYLSILANYL-BUT-3-YN-2-ONE 3-TERT-BUTYLDIMETHYLSILYLPROPYNAL 1-BROMO-1-PHENYL-4-TRIMETHYLSILANYL-BUT-3-YN-2-ONE 4-CHLORO-1-TRIMETHYLSILANYL-HEX-1-YN-3-ONE 1-CYCLOPROPYL-3-TRIMETHYLSILANYL-PROPYNONE 4-CHLORO-1-TRIMETHYLSILANYL-PENT-1-YN-3-ONE

3-Trimethylsilylpropynol

3-TRIMETHYLSILYLPROPYNAL

3-(TRIMETHYLSILYL)-2-PROPYNAL

3-(TRIMETHYLSILYL)PROPARGYL ALDEHYDE

3-(triMethylsilyl)propiolaldehyde

3-(Trimethylsilyl)-2-propynal 97%

3-Trimethylsilylprop-2-Ynal

(Trimethylsilyl)propiolaldehyde

(Trimethylsilyl)propynal

Trimethylsilylpropynal

3-TriMethylsilylpropynal, 98.0%,(GC)

2-Propynal, 3-(trimethylsilyl)-

)-2-propynaL

Trimethylsilanyl-propynal

DK722

DKFELEX0187

2975-46-4

CH33SiCCCHO

C6H10OSi