ChemicalBook > CAS DataBase List > 3-TRIMETHYLSILYLPROPYNAL

3-TRIMETHYLSILYLPROPYNAL

Product Name: 3-TRIMETHYLSILYLPROPYNAL
CAS No.: 2975-46-4
Chemical Name: 3-TRIMETHYLSILYLPROPYNAL
Synonyms: 3-(triMethylsilyl)propiolaldehyde;DK722;DKFELEX0187;)-2-propynaL;Trimethylsilylpropynal;3-TRIMETHYLSILYLPROPYNAL;3-Trimethylsilylpropynol;(Trimethylsilyl)propynal;Trimethylsilanyl-propynal;3-Trimethylsilylprop-2-Ynal
CBNumber: CB4288965
Molecular Formula: C6H10OSi
Formula Weight: 126.23
MOL File: 2975-46-4.mol

Less

3-TRIMETHYLSILYLPROPYNAL Property

Melting point:: 195 °C
Boiling point:: 52 °C
Density: 0.854 g/mL at 25 °C
refractive index: n20/D 1.444
Flash point:: >25°C
storage temp.: 2-8°C
form: Liquid
Specific Gravity: 0.86
color: Colorless to yellow
Sensitive: Air & Moisture Sensitive
Hydrolytic Sensitivity: 4: no reaction with water under neutral conditions
InChI: InChI=1S/C6H10OSi/c1-8(2,3)6-4-5-7/h5H,1-3H3
InChIKey: LJRWLSKYGWLYIM-UHFFFAOYSA-N
SMILES: C(=O)C#C[Si](C)(C)C

Less

Safety

Hazard Codes: Xi
Risk Statements: 10-36/37/38
Safety Statements: 16-36/37/39-36/37-26
RIDADR: 1993
WGK Germany: 3
TSCA: No
HazardClass: 3
PackingGroup: II
HS Code: 29319090

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H226Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 687170
Product name: 3-(Trimethylsilyl)-2-propynal
Purity: 97%
Packaging: 1g
Price: $40
Updated: 2023/06/20

TCI Chemical

Product number: T2907
Product name: 3-Trimethylsilylpropynal
Purity: >97.0%(GC)
Packaging: 1g
Price: $179
Updated: 2025/07/31

TCI Chemical

Product number: T2907
Product name: 3-Trimethylsilylpropynal
Purity: >97.0%(GC)
Packaging: 5g
Price: $533
Updated: 2025/07/31

TRC

Product number: T896568
Product name: 3-(Trimethylsilyl)-2-propynal
Packaging: 500mg
Price: $60
Updated: 2021/12/16

Frontier Specialty Chemicals

Product number: JK345372
Product name: 3-Trimethylsilylpropynal
Packaging: 1g
Price: $113
Updated: 2021/12/16

Less

3-TRIMETHYLSILYLPROPYNAL Chemical Properties,Usage,Production

Uses

3-Trimethylsilylpropynal acts as an important organic intermediate. It is used in agrochemicals, pharmaceuticals and dyestuff field. Further, it is used in the preparation of [3-(trimethylsilyl)-2-propinyliden]-malononitrile.

Synthesis

68-12-2

1066-54-2

2975-46-4

Steps for the synthesis of 3-trimethylsilylpropynal: 1. A solution of trimethylsilylacetylene (5.0 mL, 36.10 mmol) in THF (25.0 mL) was added dropwise to a solution of EtMgBr in THF (1 M, 44.0 mL, 44.0 mmol) under nitrogen protection, and the reaction temperature was maintained at 10-150°C. 2. After the dropwise addition, the reaction mixture was stirred at room temperature for 1 hour. 3. A solution of Et2O (20.0 mL) in DMF (10.0 mL, 123.0 mmol) was slowly added to the reaction system at -25 °C, and the addition time was controlled to be within 30 min. 4. The resulting white suspension was gradually warmed to room temperature and stirring was continued for 1 hour. 5. The reaction mixture was heated to 30 °C and maintained for 15 minutes. 6. The reaction solution was cooled to 0 °C and poured into 5% H2SO4 solution. 7. The aqueous layer was separated and extracted three times with Et2O. 8. Combine the organic layers, wash with saturated aqueous NH4Cl solution and dry with anhydrous Na2SO4. 9. Concentrate under pressure to remove the solvent and obtain the crude product. 10. purification of the crude product by ball-to-ball distillation (20 mbar, room temperature) afforded 3-trimethylsilylpropynal (2.255 g, 49% yield). Product characterization data: 1H NMR: δ 9.15 (s, 1H), 0.25 (s, 9H). 13C NMR: δ 176.7, 103.0, 102.3, 0.88.

References

[1] Tetrahedron Letters, 1995, vol. 36, # 3, p. 401 - 404
[2] Angewandte Chemie - International Edition, 2008, vol. 47, # 6, p. 1130 - 1133
[3] Tetrahedron, 2002, vol. 58, # 12, p. 2415 - 2422
[4] Arkivoc, 2012, vol. 2012, # 7, p. 253 - 273
[5] Patent: WO2009/141781, 2009, A1. Location in patent: Page/Page column 18

3-TRIMETHYLSILYLPROPYNAL Preparation Products And Raw materials

Raw materials

Preparation Products

Less

3-TRIMETHYLSILYLPROPYNAL Suppliers

China 142 Germany 1 India 1 Japan 1 Singapore 1 Slovakia 1 Switzerland 1 United Kingdom 2 United States 16 Global 166

Shanghai Guijing New Material Technology Co., Ltd.

Tel: 18616507986
Email: 2433448178@qq.com
Country: China
ProdList: 867
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Beijing HwrkChemical Technology Co., Ltd

Tel: 18515581800 18501085097
Fax: 010-89508210
Email: sales.bj@hwrkchemical.com
Country: China
ProdList: 9400
Advantage: 55

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9310
Advantage: 66

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

China DongFan Chemical Co.,LTD

Tel: 86-0571-85151182
Fax: 86-0571-85151182
Country: China
ProdList: 5691
Advantage: 66

Shandong Xiya Chemical Co., Ltd

Tel: 4009903999 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18729
Advantage: 57

Syntechem Co.,Ltd

Tel
Fax: E-Mail Inquiry
Email: info@syntechem.com
Country: China
ProdList: 12984
Advantage: 57

Chengdu Ai Keda Chemical Technology Co., Ltd.

Tel: 4008-755-333 18080918076
Fax: 028-86757656
Email: 800078821@qq.com
Country: China
ProdList: 9718
Advantage: 55

Guangzhou Egg Biotechnology Co., Ltd.

Tel: 86-20-28069315 28069316
Fax: 86-20-28069316
Email: eggbio@163.com
Country: China
ProdList: 20
Advantage: 58

Shanghai T&W Pharmaceutical Co., Ltd.

Tel: +86 21 61551611
Fax: +86 21 50676805
Country: China
ProdList: 9891
Advantage: 58

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 22514
Advantage: 55

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-6206333 13167063860
Fax: 021-50323701
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

The future of Shanghai Industrial Co., Ltd.

Tel: 021-61552785
Fax: 021-55660885
Email: sales@shshiji.com
Country: China
ProdList: 9546
Advantage: 55

Shanghai Yolne Chemical Co., Ltd.

Tel: 021-62960152
Fax: 021-52212593
Email: 934678158@qq.com
Country: China
ProdList: 9899
Advantage: 55

Shanghai XIYU Chemical Technology Co.,Ltd.

Tel: 021-15000143735 15221126179
Fax: 021-38473230
Email: sala@xiyuchem.com
Country: China
ProdList: 374
Advantage: 55

Huainan Kedi Chemical Factory

Tel: 0554-2106669
Fax: 0554-2666215
Email: sales1@kedichem.com
Country: China
ProdList: 4924
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

ShangHai D&B Biological Science and Technology Co.Ltd

Tel: 400-008-9730,021-54359730 400-008-9730
Fax: 021-54353864
Email: info@chemxyz.com
Country: China
ProdList: 3057
Advantage: 60

Shanghai Gileader Advanced Material Technology Co.,Ltd

Tel: 18516111942
Email: 823898732@qq.com
Country: China
ProdList: 1328
Advantage: 56

Shanghai Worldyang Chemical Co.,Ltd.

Tel: 021-021-56795766
Fax: +86-21-56795266
Email: sales@worldyachem.com
Country: China
ProdList: 9476
Advantage: 58

Chengdu HuaXia Chemical Reagent Co. Ltd

Tel: 400-1166-196 13458535857
Fax: QQ：800101999
Email: cdhxsj@163.com
Country: China
ProdList: 13350
Advantage: 58

Hangzhou J&H Chemical Co., Ltd.

Tel: 0571-87396432
Fax: 0571-87396431
Email: sales@jhechem.com
Country: China
ProdList: 14912
Advantage: 59

Shanghai Song Yuan Chemical Technology Co., Ltd.

Tel: 010-1234567 18521000990
Fax: 86-021-33275113
Email: sonyuanchemical@163.com
Country: China
ProdList: 6479
Advantage: 50

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51395
Advantage: 80

Shanghai Uchem Inc.

Tel: 15618758386; 15618758386
Fax: QQ:3004479444
Email: sales3@myuchem.com
Country: China
ProdList: 1999
Advantage: 55

Chengdu RunZeBenTu Chemical Co., Ltd

Tel: 028-88469284 18000562381
Email: rzbtsj@163.com
Country: China
ProdList: 9951
Advantage: 56

CHMA Chemical Technology (Shanghai) Co., Ltd

Tel: 021-61556450 15800904410
Fax: 021-61556450
Country: China
ProdList: 2832
Advantage: 58

Codow Chemical Co.,Ltd.

Tel: 18620099427
Fax: +86-20-62619665
Email: amy@howeipharm.com
Country: China
ProdList: 6687
Advantage: 55

skychemical Co.Ltd

Tel: 021-20960837,QQ1332204249
Fax: 021-20960837
Email: sales@skychemical.com
Country: China
ProdList: 3341
Advantage: 55

Nanjing Vital Chemical Co., Ltd.

Tel: 025-87193546 18652950785
Fax: 025-87193546
Email: chemweiao@163.com
Country: China
ProdList: 9021
Advantage: 60

ShangHai Siyan Biological Technology Co., Ltd.

Tel: 021-50908862，442785678，326799392 18721037013
Fax: 021-50908862
Email: siyansales@126.com
Country: China
ProdList: 9627
Advantage: 58

Nanjing XiLang Chemical Products Co., Ltd.

Tel: 18936048580
Email: chemxilang@163.com
Country: China
ProdList: 3909
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

parabiochem

Tel: 025-83453382-8005
Fax: 025-83453382
Email: sale@parabiochem.com
Country: China
ProdList: 9595
Advantage: 55

Zhengzhou AnMusi Chemical Products Co., Ltd.

Tel: 0371-55289822 18737195735
Fax: QQ：2370407954
Email: 2370407954@qq.com
Country: China
ProdList: 1981
Advantage: 55

Grader reagent

Tel: 18221735425
Email: sales@xinpingchem.com
Country: China
ProdList: 9942
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Shanghai Kangman Biological Technology Co., Ltd.

Tel: 18800375331
Fax: 021-50908862
Email: kangmansales@163.com
Country: China
ProdList: 7570
Advantage: 55

Shandong Ono Chemical Co., Ltd.

Tel: 0539-6362799 20）
Fax: 0539-6362799（To 20）
Country: China
ProdList: 10007
Advantage: 58

Shanghai BaiShun Biological Technology Co., Ltd

Tel: 021-37581181
Fax: 021-57456066
Email: sales@chem-mall.com
Country: China
ProdList: 10330
Advantage: 58

Aikon International Limited

Tel: 025-58851090 15955137747
Fax: (6)02557626880
Email: sales01@aikonchem.com
Country: China
ProdList: 15949
Advantage: 58

Suzhou Siso new material Co.,Ltd.

Tel: 0512-65402974 18550909935;
Fax: 0512-67544899
Email: siso03@126.com
Country: China
ProdList: 1913
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 400821072
Fax: 021-58955996
Email: malulu@leyan.com
Country: China
ProdList: 25000
Advantage: 58

Nanjing SynTitan Pharmaceutical Co., Ltd.

Tel: 025-57027686 17372956142
Fax: 025-57027686
Email: li_lan@syntitan.com
Country: China
ProdList: 9998
Advantage: 58

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400-6387771-6039 18920764717
Email: sales@heowns.com
Country: China
ProdList: 23771
Advantage: 60

Less

View Lastest Price from 3-TRIMETHYLSILYLPROPYNAL manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 3-TRIMETHYLSILYLPROPYNAL 2975-46-4
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 mt
Release date: 2025-03-07

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: 3-TRIMETHYLSILYLPROPYNAL 2975-46-4
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20ton
Release date: 2024-06-05

Career Henan Chemical Co

Product: 3-TRIMETHYLSILYLPROPYNAL 2975-46-4
Price: US $2.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: customsie
Release date: 2018-08-20

2975-46-4, 3-TRIMETHYLSILYLPROPYNALRelated Search:

(TERT-BUTYLDIMETHYLSILYLOXY)ACETALDEHYDE Propyne 3-(TRIMETHYLSILYL)PROPIOLIC ACID METHYL 3-(TRIMETHYLSILYL)PROPIOLATE 4-(Trimethylsilyl)-3-butyn-2-one 3-TRIMETHYLSILYLPROPYNAL 1-CHLORO-4-TRIMETHYLSILANYL-BUT-3-YN-2-ONE ETHYL 3-(TRIMETHYLSILYL)PROPIOLATE TRIMETHYLSILYL(TRIMETHYLSILYL)PROPYNOATE 3-(Triethylsilyl)-2-propynal PROPYNAL 1-PHENYL-4-TRIMETHYLSILANYL-BUT-3-YN-2-ONE 3-TERT-BUTYLDIMETHYLSILYLPROPYNAL 1-BROMO-1-PHENYL-4-TRIMETHYLSILANYL-BUT-3-YN-2-ONE 4-CHLORO-1-TRIMETHYLSILANYL-HEX-1-YN-3-ONE 1-CYCLOPROPYL-3-TRIMETHYLSILANYL-PROPYNONE 4-CHLORO-1-TRIMETHYLSILANYL-PENT-1-YN-3-ONE

3-Trimethylsilylpropynol

3-TRIMETHYLSILYLPROPYNAL

3-(TRIMETHYLSILYL)-2-PROPYNAL

3-(TRIMETHYLSILYL)PROPARGYL ALDEHYDE

3-(triMethylsilyl)propiolaldehyde

3-(Trimethylsilyl)-2-propynal 97%

3-Trimethylsilylprop-2-Ynal

(Trimethylsilyl)propiolaldehyde

(Trimethylsilyl)propynal

Trimethylsilylpropynal

3-TriMethylsilylpropynal, 98.0%,(GC)

2-Propynal, 3-(trimethylsilyl)-

)-2-propynaL

Trimethylsilanyl-propynal

DK722

DKFELEX0187

2975-46-4

CH33SiCCCHO

C6H10OSi