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4-ACETAMIDOPIPERIDINE

Product Name
4-ACETAMIDOPIPERIDINE
CAS No.
5810-56-0
Chemical Name
4-ACETAMIDOPIPERIDINE
Synonyms
4-ACETAMIDOPIPERIDINE;4-Acetylamino-piperidine;4-Acetamidopiperidine >N-PIPERIDIN-4-YL-ACETAMIDE;Acetamide, N-4-piperidinyl-;N-piperidine-4-yl-acetamide;4-(N-Ethanoylamino)piperidine;4-ACETYLAMINO-PIPERIDINE >98%;N-(4-Piperidinyl)acetamide
CBNumber
CB1407855
Molecular Formula
C7H14N2O
Formula Weight
142.2
MOL File
5810-56-0.mol
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4-ACETAMIDOPIPERIDINE Property

Melting point:
141 °C
Boiling point:
318.5±31.0 °C(Predicted)
Density 
1.02
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
soluble in Methanol
form 
powder to crystal
pka
15.96±0.20(Predicted)
color 
White to Almost white
CAS DataBase Reference
5810-56-0(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-22
Safety Statements 
36/37/39-37-26
HS Code 
29333990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
CDS000127
Product name
N-(4-Piperidinyl)acetamide
Purity
AldrichCPR
Packaging
100mg
Price
$68.1
Updated
2023/06/20
TCI Chemical
Product number
A1653
Product name
4-Acetamidopiperidine
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$105
Updated
2025/07/31
TCI Chemical
Product number
A1653
Product name
4-Acetamidopiperidine
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$313
Updated
2025/07/31
TRC
Product number
A192310
Product name
4-Acetamidopiperidine
Packaging
1g
Price
$155
Updated
2021/12/16
AK Scientific
Product number
Y9534
Product name
N-(Piperidin-4-yl)acetamide
Packaging
5g
Price
$72
Updated
2021/12/16
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4-ACETAMIDOPIPERIDINE Chemical Properties,Usage,Production

Synthesis

50534-23-1

5810-56-0

General procedure for the synthesis of 4-acetamido-piperidine from 4-acetamido-1-benzylpiperidine: preparation of intermediate 40: N-piperidin-4-yl-acetamide (method step 10). Pd-C (350 mg) was added to a solution of N-(1-benzyl-piperidin-4-yl)-acetamide (intermediate 39) (2.3 g, 10.0 mmol) in EtOH (35 mL) and HCl (1 M, 5 mL), and the mixture was stirred for 5 hr under hydrogen atmosphere. Upon completion of the reaction, the catalyst was removed by filtration through diatomaceous earth followed by washing with EtOH and then water. The filtrate was concentrated under vacuum and the product was purified by column chromatography using a methanol solution of dichloromethane/7M NH3 (100:0 to 80:20) as eluent to give the intermediate 40 (0.92 g, 65% yield). Since the compound could not be detected by HPLC-MS, its structure was confirmed by NMR.

References

[1] Bioorganic and Medicinal Chemistry Letters, 2003, vol. 13, # 14, p. 2303 - 2306
[2] Organic Process Research and Development, 2012, vol. 16, # 3, p. 470 - 483
[3] Patent: US2012/214798, 2012, A1
[4] Patent: US2005/43298, 2005, A1. Location in patent: Page/Page column 35
[5] Patent: US2005/197333, 2005, A1. Location in patent: Page/Page column 39-40

4-ACETAMIDOPIPERIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-ACETAMIDOPIPERIDINE Suppliers

J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
Advantage
66
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
Advantage
57
Lavem Chine Pharm Company
Tel
028-62070218 18190869852
Fax
86-28-8527-5264
Email
sales@lavemc.com
Country
China
ProdList
214
Advantage
67
Chengdu HappySyn Pharmaceutical Technology Co., Ltd.
Tel
028-85114309 18982182443
Email
yangli@happysyn.com
Country
China
ProdList
2150
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55
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19913
Advantage
55
TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28387
Advantage
80
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View Lastest Price from 4-ACETAMIDOPIPERIDINE manufacturers

Career Henan Chemical Co
Product
4-ACETAMIDOPIPERIDINE 5810-56-0
Price
US $1.00/kg
Min. Order
1kg
Purity
95%-99%
Supply Ability
as request
Release date
2018-12-24