N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride

Product Name: N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride
CAS No.: 58934-46-6
Chemical Name: N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride
Synonyms: Nsc310411;Lorcainide HCl;EINECS 261-504-6;Isocainide hydrochloride;LORCAINIDE HYDROCHLORIDE;4'-Chloro-N-(1-isopropyl-4-piperidyl)-2-phenylacetanilide monohydrochloride;N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride;N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride USP/EP/BP;Benzeneacetamide, N-(4-chlorophenyl)-N-[1-(1-methylethyl)-4-piperidinyl]-, monohydrochloride
CBNumber: CB3904853
Molecular Formula: C22H28Cl2N2O
Formula Weight: 407.37652
MOL File: 58934-46-6.mol

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N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride Property

Melting point:: 263°
storage temp.: -20°C
solubility: Soluble in DMSO (up to 20 mg/ml), in Water (up to 20 mg/ml), or in Ethanol (up to 20 mg/ml).
form: White solid.
color: Powder
Water Solubility: H2O: 10mg/mL, clear
Stability:: Stable for 1 year from date of purchase as supplied. Solutions in DMSO, distilled water or ethanol may be stored at -20°C for up to 1 month

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P330Rinse mouth.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML1025
Product name: Lorcainide hydrochloride
Purity: ≥98% (HPLC)
Packaging: 10 mg
Price: $92.7
Updated: 2025/07/31

Sigma-Aldrich

Product number: SML1025
Product name: Lorcainide hydrochloride
Purity: ≥98% (HPLC)
Packaging: 50 mg
Price: $365
Updated: 2025/07/31

American Custom Chemicals Corporation

Product number: HCH0041839
Product name: N-(4-CHLOROPHENYL)-2-PHENYL-N-(1-PROPAN-2-YL-3,4,5,6-TETRAHYDRO-2H-PYRIDIN-4-YL)ACETAMIDE CHLORIDE
Purity: 95.00%
Packaging: 5MG
Price: $500.72
Updated: 2021/12/16

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N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride Chemical Properties,Usage,Production

Description

Lorcainide hydrochloride (58934-46-6) is a voltage-gated Na+?channel blocker.1?Protects murine cultured cortical neurons from injury induced by oxygen-glucose deprivation.2?Acts at the ouabain binding site of guinea pig cardiac Na+/K+?ATPase and inhibits the enzyme (IC50?= 34 μM).3

Uses

Cardiac depressant (anti-arrhythmic).

References

[1] R S SHELDON H J D R J Hill. Antiarrhythmic drugs and the cardiac sodium channel: current models.[J]. Clinical chemistry, 1989, 35 5: 748-754.
[2] J J LYNCH. Sodium channel blockers reduce oxygen-glucose deprivation-induced cortical neuronal injury when combined with glutamate receptor antagonists.[J]. Journal of Pharmacology and Experimental Therapeutics, 1995, 273 1: 554-560.
[3] A. ALMOTREFI. Class I antiarrhythmic drug effects on ouabain binding to guinea pig cardiac Na+ -K+ ATPase.[J]. Canadian journal of physiology and pharmacology, 1999, 77 11 1: 866-870. DOI:10.1139/y99-091

N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride Suppliers

China 9 United States 5 Global 14

Shanghai EFE Biological Technology Co., Ltd.

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TargetMol Chemicals Inc.

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Shaanxi Dideu Medichem Co. Ltd

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Enzo Biochem Inc

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Merck KGaA

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Santa Cruz Biotechnology Inc

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Aladdin Scientific

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Guangzhou Weisheng Biotechnology Co., Ltd.

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58934-46-6, N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochlorideRelated Search:

N-ETHYL-N-ISOPROPYLANILINE N,N-Dimethylpiperidin-4-amine 1,3-Propanediamine,N3,N3-diethyl-1-phenyl- 1,3-DIAMINOPROPANE DIHYDROCHLORIDE 4-(dimethylammonio)piperidinium dichloride 4-Aminopiperidine dihydrochloride N,N,N',N'-TETRAMETHYL-1,3-BUTANEDIAMINE 2,N-DIPHENYLACETAMIDE 4-ACETAMIDOPIPERIDINE 1-Methyl-4-(methylamino)piperidine N-(1-METHYLPIPERIDIN-4-YL)ANILINE 1,3-Propanediamine,N3,N3-dimethyl-1-phenyl- N-Phenyl-N-(4-piperidinyl)propanamide admixture with HCl salt 1-ISOPROPYL-PIPERIDIN-4-YLAMINE Lorcainide N-METHYL-N-4-PIPERIDINYLACETAMIDE 1-methyl-N-(2-phenylethyl)piperidin-4-amine N,N-DIMETHYL-2-PHENYLACETAMIDE

N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride

LORCAINIDE HYDROCHLORIDE

Isocainide hydrochloride

4'-Chloro-N-(1-isopropyl-4-piperidyl)-2-phenylacetanilide monohydrochloride

Benzeneacetamide, N-(4-chlorophenyl)-N-[1-(1-methylethyl)-4-piperidinyl]-, monohydrochloride

Nsc310411

N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride USP/EP/BP

Lorcainide HCl

EINECS 261-504-6

58934-46-6

C22H28Cl2N2O