ChemicalBook > CAS DataBase List > N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride

N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride

Product Name
N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride
CAS No.
58934-46-6
Chemical Name
N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride
Synonyms
Nsc310411;Lorcainide HCl;EINECS 261-504-6;Isocainide hydrochloride;LORCAINIDE HYDROCHLORIDE;4'-Chloro-N-(1-isopropyl-4-piperidyl)-2-phenylacetanilide monohydrochloride;N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride;N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride USP/EP/BP;Benzeneacetamide, N-(4-chlorophenyl)-N-[1-(1-methylethyl)-4-piperidinyl]-, monohydrochloride
CBNumber
CB3904853
Molecular Formula
C22H28Cl2N2O
Formula Weight
407.37652
MOL File
58934-46-6.mol
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N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride Property

Melting point:
263°
storage temp. 
-20°C
solubility 
Soluble in DMSO (up to 20 mg/ml), in Water (up to 20 mg/ml), or in Ethanol (up to 20 mg/ml).
form 
White solid.
color 
Powder
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO, distilled water or ethanol may be stored at -20°C for up to 1 month
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P330Rinse mouth.

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N-Bromosuccinimide Price

Alfa Aesar
Product number
J67098
Product name
Lorcainide hydrochloride, 98%
Packaging
10mg
Price
$126
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0041839
Product name
N-(4-CHLOROPHENYL)-2-PHENYL-N-(1-PROPAN-2-YL-3,4,5,6-TETRAHYDRO-2H-PYRIDIN-4-YL)ACETAMIDE CHLORIDE
Purity
95.00%
Packaging
5MG
Price
$500.72
Updated
2021/12/16
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N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride Chemical Properties,Usage,Production

Description

Lorcainide hydrochloride (58934-46-6) is a voltage-gated Na+?channel blocker.1?Protects murine cultured cortical neurons from injury induced by oxygen-glucose deprivation.2?Acts at the ouabain binding site of guinea pig cardiac Na+/K+?ATPase and inhibits the enzyme (IC50?= 34 μM).3

Uses

Cardiac depressant (anti-arrhythmic).

References

1) Sheldon?et al.?(1989),?Antiarrhythmic drugs and the cardiac sodium channel: current models; Clin. Chem.,?35?748 2) Lynch?et al.?(1995),?Sodium channel clockers reduce oxygen-glucose deprivation-induced cortical neuronal injury when combined with glutamate receptor antagonists; J. Pharmacol. Exp. Ther.,?273?554 3) Almotrefi?et al. (1999),?Class I antiarrhythmic drug effects on ouabain binding to guinea pig cardiac Na+ -K+ ATPase; Can. J. Physiol. Pharmacol.,?77?866

N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride Suppliers

China 3 United States 5 Global 8
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
Shaanxi Dideu Medichem Co. Ltd
Tel
+86-029-89586680 +86-18192503167
Fax
+86-29-88380327
Email
1026@dideu.com
Country
China
ProdList
7724
Advantage
58
Shanghai Hao Zhun Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
info@zzsrm.com
Country
CHINA
ProdList
6650
Advantage
58

58934-46-6, N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochlorideRelated Search:

N-ETHYL-N-ISOPROPYLANILINE N,N-Dimethylpiperidin-4-amine 1,3-Propanediamine,N3,N3-diethyl-1-phenyl- 1,3-DIAMINOPROPANE DIHYDROCHLORIDE 4-(dimethylammonio)piperidinium dichloride 4-Aminopiperidine dihydrochloride N,N,N',N'-TETRAMETHYL-1,3-BUTANEDIAMINE 2,N-DIPHENYLACETAMIDE 4-ACETAMIDOPIPERIDINE 1-Methyl-4-(methylamino)piperidine N-(1-METHYLPIPERIDIN-4-YL)ANILINE 1,3-Propanediamine,N3,N3-dimethyl-1-phenyl- N-Phenyl-N-(4-piperidinyl)propanamide admixture with HCl salt 1-ISOPROPYL-PIPERIDIN-4-YLAMINE Lorcainide N-METHYL-N-4-PIPERIDINYLACETAMIDE 1-methyl-N-(2-phenylethyl)piperidin-4-amine N,N-DIMETHYL-2-PHENYLACETAMIDE

  • N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride
  • LORCAINIDE HYDROCHLORIDE
  • Isocainide hydrochloride
  • 4'-Chloro-N-(1-isopropyl-4-piperidyl)-2-phenylacetanilide monohydrochloride
  • Benzeneacetamide, N-(4-chlorophenyl)-N-[1-(1-methylethyl)-4-piperidinyl]-, monohydrochloride
  • Nsc310411
  • N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride USP/EP/BP
  • Lorcainide HCl
  • EINECS 261-504-6
  • 58934-46-6
  • C22H28Cl2N2O