ChemicalBook > CAS DataBase List > Cinobufotalin

Cinobufotalin

Product Name
Cinobufotalin
CAS No.
1108-68-5
Chemical Name
Cinobufotalin
Synonyms
Nsc90326;Cinobufotlin;CINOBUFOTALIN;Chinbufotalin;CINOBUFOTALIN(RG);Cinobufotalin std.;Cinobufotalin Standard;Cinobufotalin USP/EP/BP;cinobufotalin venom toad;5beta-Hydroxycinobufagin
CBNumber
CB1410581
Molecular Formula
C26H34O7
Formula Weight
458.54
MOL File
1108-68-5.mol
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Cinobufotalin Property

Melting point:
259-262°
alpha 
D20 +11°
Boiling point:
627.3±55.0 °C(Predicted)
Density 
1.34±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMF: 10 mg/ml; DMF:PBS (pH 7.2) (1:1): 0.5 mg/ml; DMSO: 5 mg/ml; Ethanol: 5 mg/ml
pka
14.67±0.70(Predicted)
form 
White to off-white solid.
CAS DataBase Reference
1108-68-5
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Safety

Hazard Codes 
T+
Risk Statements 
26/27/28
Safety Statements 
22-36/37/39-45
RIDADR 
UN 2811 6.1/PG 1
WGK Germany 
3
RTECS 
EI2991000
HazardClass 
6.1(a)
PackingGroup 
II
Toxicity
cat,LD50,intravenous,200ug/kg (0.2mg/kg),"Die Herzwirksamen Glykoside," Baumgarten, G., and W. Forster, Leipzig, Ger. Dem. Rep., VEB Georg Thieme, 1963Vol. -, Pg. 189, 1963.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P262Do not get in eyes, on skin, or on clothing.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C1147
Product name
Cinobufotalin
Packaging
10mg
Price
$416
Updated
2024/03/01
Cayman Chemical
Product number
19845
Product name
Cinobufotalin
Packaging
5mg
Price
$112
Updated
2024/03/01
Cayman Chemical
Product number
19845
Product name
Cinobufotalin
Packaging
25mg
Price
$341
Updated
2024/03/01
Cayman Chemical
Product number
19845
Product name
Cinobufotalin
Packaging
1mg
Price
$36
Updated
2024/03/01
Cayman Chemical
Product number
19845
Product name
Cinobufotalin
Packaging
10mg
Price
$172
Updated
2024/03/01
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Cinobufotalin Chemical Properties,Usage,Production

Description

Cinobufacin is an indole-type total alkaloid extracted from the dried toad skin of Chinese toad, which has the functions of clearing away heat and detoxifying, reducing swelling and pain, promoting blood circulation and removing blood stasis, softening and dispelling knots.

Application

Cinobufacin can be used for a variety of middle and advanced tumors (lung cancer, breast cancer, cervical cancer, digestive system tumors such as primary liver cancer, gastric cancer, colon cancer, etc.), chronic hepatitis B, especially for chronic hepatitis B virus carriers. Especially prominent.

Side effects

For individual patients, if the dosage is too large or the interval between two administrations is less than 6 to 8 hours, chills and fever may occur about 30 minutes after administration; a small number of patients have local irritation or phlebitis after long-term intravenous infusion, which will slow down the infusion rate. Very few patients may also appear urticaria, dermatitis and so on.

Cinobufotalin Preparation Products And Raw materials

Raw materials

Preparation Products

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Cinobufotalin Suppliers

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View Lastest Price from Cinobufotalin manufacturers

Shanghai Standard Technology Co., Ltd.
Product
Cinobufotalin 1108-68-5
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2020-03-20
Dideu Industries Group Limited
Product
Cinobufotalin 1108-68-5
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons Min
Release date
2021-07-02
Shaanxi Dideu Medichem Co. Ltd
Product
Cinobufotalin 1108-68-5
Price
US $0.00-0.00/Kg
Min. Order
1KG
Purity
99.0%
Supply Ability
800 ton
Release date
2020-04-30

1108-68-5, CinobufotalinRelated Search:

Ethyl acetate Sodium acetate Vinyl acetate Methyl acetate Glatiramer acetate Butyl acetate Potassium Acetate Tocopheryl acetate ACETATE bufoin injection ALPHA-PYRONE 1,2-EPOXYTETRADECANE (R)-(+)-1,2-Epoxybutane 1,2-Epoxydodecane TERPIN MONOHYDRATE 2,3-EPOXY-2-METHYLBUTANE CIS-1,2-CYCLOPENTANEDIOL (R)-(+)-Glycidol

  • cinobufotalin venom toad
  • Cinobufotalin std.
  • 5BETA,20[22]-BUFADIENOLIDE-14,15BETA-EPOXY-3BETA,5ALPHA,16BETA-TRIOL 16-ACETATE
  • 14,15-beta-epoxy-3-beta,5,16-beta-trihydroxy-22-dienolid16-5-beta-bufa-2
  • CINOBUFOTALIN(RG)
  • 14,15b-Epoxy-3b,5a,16b-trihydroxy-5b,20(22)-bufadienolide 16-acetate
  • 5β,20(22)-Bufadienolide-14,15β-epoxy-3β,5α,16β-triol 16-acetate, 14,15β-Epoxy-3β,5α,16β-trihydroxy-5β,20(22)-bufadienolide 16-acetate
  • 14,15-Epoxy-14H-cyclopenta[a]phenanthrene, bufa-20,22-dienolide deriv.
  • 5-b-Bufa-20,22-dienolide, 14,15-b-epoxy-3-b,5,16-b-trihydroxy, 16-acetate
  • Bufa-20,22-dienolide, 16- (acetyloxy)-14,15-epoxy-3,5-dihydroxy-, (3.beta.,5.beta.,15.beta.,16.beta.)-
  • 16β-(Acetyloxy)-14,15β-epoxy-3β,5-dihydroxy-5β,14β-bufa-20,22-dienolide
  • 16β-Acetoxy-14,15β-epoxy-3β,5-dihydroxy-5β-bufa-20,22-dienolide
  • 3β,5β-Dihydroxy-16β-acetoxy-14,15β-epoxy-5β-bufa-20,22-dienolide
  • 5.beta.-Bufa-20,22-dienolide, 14,15.beta.-epoxy-3.beta.,5,16.beta.-trihydroxy-, 16-acetate
  • Cinobufotlin
  • Nsc90326
  • 14,15β-Epoxy-3β,5α,16β-trihydroxy-5β,20(22)-bufadienolide 16-acetate
  • 5β,20(22)-Bufadienolide-14,15β-epoxy-3β,5α,16β-triol 16-acetate
  • CINOBUFOTALIN
  • 20,22,5BETA-BUFADIENOLID-14BETA,15BETA-EPOXY-3BETA, 5BETA, 6BETA-TRIOL-16-ACETATE
  • Cinobufotalin, 98%, from animal extracts
  • 14,15BETA-EPOXY-3BETA,5ALPHA,16BETA-TRIHYDROXY-5BETA,20[22]-BUFADIENOLIDE 16-ACETATE
  • 5beta-Hydroxycinobufagin, HPLC≥98%
  • Cinobufotalin Standard
  • Bufa-20,22-dienolide, 16-(acetyloxy)-14,15-epoxy-3,5-dihydroxy-, (3β,5β,15β,16β)-
  • Cinobufotalin USP/EP/BP
  • 5beta-Hydroxycinobufagin
  • Chinbufotalin
  • 1108-68-5
  • C26H34O7