ChemicalBook > CAS DataBase List > Cinobufotalin

Cinobufotalin

Product Name
Cinobufotalin
CAS No.
1108-68-5
Chemical Name
Cinobufotalin
Synonyms
Nsc90326;Cinobufotlin;CINOBUFOTALIN;Chinbufotalin;CINOBUFOTALIN(RG);Cinobufotalin std.;Cinobufotalin Standard;Cinobufotalin USP/EP/BP;cinobufotalin venom toad;5beta-Hydroxycinobufagin
CBNumber
CB1410581
Molecular Formula
C26H34O7
Formula Weight
458.54
MOL File
1108-68-5.mol
More
Less

Cinobufotalin Property

Melting point:
259-262°
alpha 
D20 +11°
Boiling point:
627.3±55.0 °C(Predicted)
Density 
1.34±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMF: 10 mg/ml; DMF:PBS (pH 7.2) (1:1): 0.5 mg/ml; DMSO: 5 mg/ml; Ethanol: 5 mg/ml
pka
14.67±0.70(Predicted)
form 
White to off-white solid.
color 
White to off-white
CAS DataBase Reference
1108-68-5
More
Less

Safety

Hazard Codes 
T+
Risk Statements 
26/27/28
Safety Statements 
22-36/37/39-45
RIDADR 
UN 2811 6.1/PG 1
WGK Germany 
3
RTECS 
EI2991000
HazardClass 
6.1(a)
PackingGroup 
II
Toxicity
cat,LD50,intravenous,200ug/kg (0.2mg/kg),"Die Herzwirksamen Glykoside," Baumgarten, G., and W. Forster, Leipzig, Ger. Dem. Rep., VEB Georg Thieme, 1963Vol. -, Pg. 189, 1963.
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P262Do not get in eyes, on skin, or on clothing.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C1147
Product name
Cinobufotalin
Packaging
10mg
Price
$416
Updated
2024/03/01
Cayman Chemical
Product number
19845
Product name
Cinobufotalin
Packaging
5mg
Price
$112
Updated
2024/03/01
Cayman Chemical
Product number
19845
Product name
Cinobufotalin
Packaging
25mg
Price
$341
Updated
2024/03/01
Cayman Chemical
Product number
19845
Product name
Cinobufotalin
Packaging
1mg
Price
$36
Updated
2024/03/01
Cayman Chemical
Product number
19845
Product name
Cinobufotalin
Packaging
10mg
Price
$172
Updated
2024/03/01
More
Less

Cinobufotalin Chemical Properties,Usage,Production

Description

Cinobufacin is an indole-type total alkaloid extracted from the dried toad skin of Chinese toad, which has the functions of clearing away heat and detoxifying, reducing swelling and pain, promoting blood circulation and removing blood stasis, softening and dispelling knots.

Application

Cinobufacin can be used for a variety of middle and advanced tumors (lung cancer, breast cancer, cervical cancer, digestive system tumors such as primary liver cancer, gastric cancer, colon cancer, etc.), chronic hepatitis B, especially for chronic hepatitis B virus carriers. Especially prominent.

Side effects

For individual patients, if the dosage is too large or the interval between two administrations is less than 6 to 8 hours, chills and fever may occur about 30 minutes after administration; a small number of patients have local irritation or phlebitis after long-term intravenous infusion, which will slow down the infusion rate. Very few patients may also appear urticaria, dermatitis and so on.

Cinobufotalin Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Cinobufotalin Suppliers

China 124 France 1 Japan 1 Switzerland 2 The Netherlands 1 United Kingdom 3 United States 21 Global 153
Nanjing Endesa Bio-tech Co., Ltd.
Tel
025-58862853 18915922038
Fax
+86-025-58862853
Email
sales@endesachem.com
Country
China
ProdList
591
Advantage
58
Chembest Research Laboratories Limited
Tel
+86-21-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6005
Advantage
61
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7811
Advantage
57
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
meilunui@163.com
Country
China
ProdList
4727
Advantage
58
Chengdu Biopurify Phytochemicals Ltd.
Tel
+86-028-82633397 18982077548
Fax
+86-28-82633165
Email
cwb1@biopurify.cn
Country
China
ProdList
2376
Advantage
60
Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7552
Advantage
61
Shanghai Tauto Biotech Co., Ltd.
Tel
021-51320588
Fax
0086-21-51320502
Email
tauto@tautobiotech.com
Country
China
ProdList
3989
Advantage
66
Shanghai BeiZhuo Biotech Co., Ltd.
Tel
021-61119791,13386096464
Fax
021-50190009
Email
bzswkf@foxmail.com
Country
China
ProdList
3921
Advantage
50
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9978
Advantage
55
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15178
Advantage
58
Shanghai Yongye Biotechnology Co., Ltd.
Tel
86-021-61559134 15921386130
Fax
021-55068248
Email
3423497944@qq.com
Country
China
ProdList
8144
Advantage
55
Wuhan ChemFaces Biochemical Co., Ltd.
Tel
18607101326 15172504745
Fax
+86-27-84254680
Email
aileen@chemfaces.com
Country
China
ProdList
7059
Advantage
55
Guangzhou QiYun Biotechnology Co., Ltd.
Tel
020-61288194 61288195
Fax
020-61288700
Email
505721671@qq.com
Country
China
ProdList
3866
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
27313
Advantage
60
Shanghai QianYan Bio-technology Co., Ltd
Tel
02781293128
Email
orders@biochemsafebuy.com
Country
China
ProdList
9923
Advantage
55
Shandong Xiya Chemical Co., Ltd.
Tel
4009903999 13395398332
Fax
0539-6365991
Email
sales@xiyashiji.com
Country
China
ProdList
20806
Advantage
60
Shanghai ChengShao Biological Technology Co., Ltd.
Tel
021-61847300 13341622919
Fax
021-61847300
Email
shcss01@163.com
Country
China
ProdList
4808
Advantage
58
WG reagent
Tel
13391486464
Fax
QQ:14748090
Email
samwjf@163.com
Country
China
ProdList
3086
Advantage
55
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 4009686088
Email
3193328036@qq.com
Country
China
ProdList
29785
Advantage
68
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
Advantage
58
Shanghai Uteam Biotechnology Co., Ltd.
Tel
021-36031160 13311776681
Email
3338195766@QQ.com
Country
China
ProdList
5175
Advantage
55
Shanghai Biological Technology Development Co., Ltd.
Tel
021-69955236-807 13918189704
Fax
021-65211385
Email
chinaruji@chinaruji.com
Country
China
ProdList
5176
Advantage
55
Chengdu Push Bio-Technology Co., Ltd.
Tel
028-85370565-229 18080489829
Email
3004654993@qq.com
Country
China
ProdList
8899
Advantage
60
Shandong Ono Chemical Co., Ltd.
Tel
0539-6362799 20）
Fax
0539-6362799（To 20）
Country
China
ProdList
9998
Advantage
58
Shenzhen Regent Biochemical Technology Co., Ltd.
Tel
0755-0755-85201366 18938635012
Fax
0755-85201366
Email
sales@regentsciences.com
Country
China
ProdList
9355
Advantage
58
Chengdu Alfa Biotechnology Co.,Ltd.
Tel
028-85142057, 18030712385
Fax
028-85142057 QQ:3591697873
Email
sales@alfabiotech.com
Country
China
ProdList
1925
Advantage
58
Chengdu Greenpure Biopharma CO.,Ltd
Tel
028-88203606; 18283602253
Email
jancyzheng@gcgreenpure.com
Country
China
ProdList
1589
Advantage
58
Shanghai Standard Technology Co.,Ltd.
Tel
021-021-57127007-6622-6622 15618937986
Fax
+86 (21) 5132-0077
Email
zhaok@nature-standard.com
Country
China
ProdList
3016
Advantage
58
Aikon International Limited
Tel
025-58851090 13611564524
Fax
(6)02557626880
Email
lwan@aikonchem.com
Country
China
ProdList
15951
Advantage
58
Shanghai Innovative Reseach Center Of Traditional
Tel
86-21-50801717-301
Fax
86-21-50800509
Email
wangjh@sirc-tcm.sh.cn
Country
China
ProdList
2070
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
4009004166/18616739031 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52693
Advantage
58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
57412
Advantage
58
Nanjing Yuanzhi Biotechnology Co. Ltd.
Tel
15805159960
Email
1211550495@qq.com
Country
China
ProdList
1795
Advantage
58
Chengdu Glip Biotechnology Co., Ltd.
Tel
028-87075086 18030859262
Email
2851503756@qq.com
Country
China
ProdList
1926
Advantage
58
Hefei TNJ Chemical Industry Co.,Ltd.
Tel
+86-0551-65418671 +8618949823763
Fax
0551-65418697
Email
sales@tnjchem.com
Country
China
ProdList
34553
Advantage
58
Hubei Ipure Biology Co., Ltd
Tel
+8613367258412
Fax
18062427325
Email
ada@ipurechemical.com
Country
China
ProdList
10319
Advantage
58
Dideu Industries Group Limited
Tel
+86-29-89586680 +86-15129568250
Email
1026@dideu.com
Country
China
ProdList
22883
Advantage
58
HONG KONG IPURE BIOLOGY CO.,LIMITED
Tel
86 18062405514 18062405514
Email
ada@ipurechemical.com
Country
CHINA
ProdList
3461
Advantage
58
Wuhan ChemNorm Biotech Co.,Ltd.
Tel
+86-27-8439 4403 18971486879
Fax
+86-27-8439 4403
Email
sales@chemnorm.com
Country
CHINA
ProdList
2935
Advantage
58
Jinan Ruisi Pharmaceutical Technology Co., LTD
Tel
0531-69900633 18340090523
Email
changyuan20@163.com
Country
China
ProdList
2585
Advantage
58
Hubei Jusheng Technology Co.,Ltd.
Tel
18871490254
Fax
027-59599243
Email
linda@hubeijusheng.com
Country
CHINA
ProdList
28172
Advantage
58
Zhejiang Lianshuo Biotechnology Co., Ltd.
Tel
18616526224
Email
lianshuo@vip.126.com
Country
China
ProdList
9607
Advantage
58
DC Chemicals
Tel
021-58447131 13564518121
Email
sales@dcchemicals.com
Country
China
ProdList
9409
Advantage
58
Chengdu Peter-like Biotechnology Co., Ltd.
Tel
028-81700200 18108052721
Email
2850505130@qq.com
Country
China
ProdList
5176
Advantage
58
Guangdong Wengjiang Chemical Reagent Co., Ltd.
Tel
0751-2886766 13927870850
Fax
0751-2886756
Email
3001267247@qq.com
Country
China
ProdList
9974
Advantage
58
Shaanxi Pioneer Biotech Co., Ltd .
Tel
+8613259417953
Fax
029-84385017
Email
sales@pioneerbiotech.com
Country
China
ProdList
3000
Advantage
58
Hubei xin bonus chemical co. LTD
Tel
86-13657291602
Fax
027-59338440
Email
linda@hubeijusheng.com
Country
CHINA
ProdList
22963
Advantage
58
Chongqing Chemdad Co., Ltd
Tel
+86-023-6139-8061 +86-86-13650506873
Email
sales@chemdad.com
Country
China
ProdList
39894
Advantage
58
Shanghai Standard Technology Co., Ltd.
Tel
18502101150
Fax
+86-21-57127007-6606
Email
ft-sales@nature-standard.com
Country
CHINA
ProdList
1923
Advantage
58
Chengdu Alfa Biotechnology Co.,Ltd.
Tel
028-028-85142057 19983342022
Fax
028-85142057
Email
3005359975@qq.com
Country
China
ProdList
1950
Advantage
58
More
Less

View Lastest Price from Cinobufotalin manufacturers

Shanghai Standard Technology Co., Ltd.
Product
Cinobufotalin 1108-68-5
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2020-03-20
Dideu Industries Group Limited
Product
Cinobufotalin 1108-68-5
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons Min
Release date
2021-07-02
Shaanxi Dideu Medichem Co. Ltd
Product
Cinobufotalin 1108-68-5
Price
US $0.00-0.00/Kg
Min. Order
1KG
Purity
99.0%
Supply Ability
800 ton
Release date
2020-04-30

1108-68-5, CinobufotalinRelated Search:

Ethyl acetate Sodium acetate Vinyl acetate Methyl acetate Glatiramer acetate Butyl acetate Potassium Acetate Tocopheryl acetate ACETATE bufoin injection ALPHA-PYRONE 1,2-EPOXYTETRADECANE (R)-(+)-1,2-Epoxybutane 1,2-Epoxydodecane TERPIN MONOHYDRATE 2,3-EPOXY-2-METHYLBUTANE CIS-1,2-CYCLOPENTANEDIOL (R)-(+)-Glycidol

  • cinobufotalin venom toad
  • Cinobufotalin std.
  • 5BETA,20[22]-BUFADIENOLIDE-14,15BETA-EPOXY-3BETA,5ALPHA,16BETA-TRIOL 16-ACETATE
  • 14,15-beta-epoxy-3-beta,5,16-beta-trihydroxy-22-dienolid16-5-beta-bufa-2
  • CINOBUFOTALIN(RG)
  • 14,15b-Epoxy-3b,5a,16b-trihydroxy-5b,20(22)-bufadienolide 16-acetate
  • 5β,20(22)-Bufadienolide-14,15β-epoxy-3β,5α,16β-triol 16-acetate, 14,15β-Epoxy-3β,5α,16β-trihydroxy-5β,20(22)-bufadienolide 16-acetate
  • 14,15-Epoxy-14H-cyclopenta[a]phenanthrene, bufa-20,22-dienolide deriv.
  • 5-b-Bufa-20,22-dienolide, 14,15-b-epoxy-3-b,5,16-b-trihydroxy, 16-acetate
  • Bufa-20,22-dienolide, 16- (acetyloxy)-14,15-epoxy-3,5-dihydroxy-, (3.beta.,5.beta.,15.beta.,16.beta.)-
  • 16β-(Acetyloxy)-14,15β-epoxy-3β,5-dihydroxy-5β,14β-bufa-20,22-dienolide
  • 16β-Acetoxy-14,15β-epoxy-3β,5-dihydroxy-5β-bufa-20,22-dienolide
  • 3β,5β-Dihydroxy-16β-acetoxy-14,15β-epoxy-5β-bufa-20,22-dienolide
  • 5.beta.-Bufa-20,22-dienolide, 14,15.beta.-epoxy-3.beta.,5,16.beta.-trihydroxy-, 16-acetate
  • Cinobufotlin
  • Nsc90326
  • 14,15β-Epoxy-3β,5α,16β-trihydroxy-5β,20(22)-bufadienolide 16-acetate
  • 5β,20(22)-Bufadienolide-14,15β-epoxy-3β,5α,16β-triol 16-acetate
  • CINOBUFOTALIN
  • 20,22,5BETA-BUFADIENOLID-14BETA,15BETA-EPOXY-3BETA, 5BETA, 6BETA-TRIOL-16-ACETATE
  • Cinobufotalin, 98%, from animal extracts
  • 14,15BETA-EPOXY-3BETA,5ALPHA,16BETA-TRIHYDROXY-5BETA,20[22]-BUFADIENOLIDE 16-ACETATE
  • 5beta-Hydroxycinobufagin, HPLC≥98%
  • Cinobufotalin Standard
  • Bufa-20,22-dienolide, 16-(acetyloxy)-14,15-epoxy-3,5-dihydroxy-, (3β,5β,15β,16β)-
  • Cinobufotalin USP/EP/BP
  • 5beta-Hydroxycinobufagin
  • Chinbufotalin
  • (1R,2R,2aR,3aS,3bR,5aS,7S,9aR,9bS,11aR)-5a,7-Dihydroxy-9a,11a-dimethyl-1-(2-oxo-2H-pyran-5-yl)hexadecahydronaphtho[1',2':6,7]indeno[1,7a-b]oxiren-2-yl acetate
  • 1108-68-5
  • C26H34O7