3-(4-Chlorophenyl)glutaric acid
- Product Name
- 3-(4-Chlorophenyl)glutaric acid
- CAS No.
- 35271-74-0
- Chemical Name
- 3-(4-Chlorophenyl)glutaric acid
- Synonyms
- CBI-BB ZERO/006271;Baclofen impurity C;Baclofen Impurity 3;Baclofen Impurity 1;Baclofen EP Impurity C;3-(4-chlorophenyl) glutarate;-(4-Chlorophenyl)glutaricacid;-(p-Chlorophenyl)glutaric Acid;b-(p-Chlorophenyl)glutaric Acid;3-(4-CHLOROPHENYL)GLUTARIC ACID
- CBNumber
- CB1419706
- Molecular Formula
- C11H11ClO4
- Formula Weight
- 242.66
- MOL File
- 35271-74-0.mol
3-(4-Chlorophenyl)glutaric acid Property
- Melting point:
- 164-166°C
- Boiling point:
- 394.4±27.0 °C(Predicted)
- Density
- 1.396±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Soluble in dimethyl sulfoxide. Slightly soluble in methanol.
- form
- Solid
- pka
- 4.01±0.10(Predicted)
- color
- White to Light Yellow
- BRN
- 1976828
- InChI
- InChI=1S/C11H11ClO4/c12-9-3-1-7(2-4-9)8(5-10(13)14)6-11(15)16/h1-4,8H,5-6H2,(H,13,14)(H,15,16)
- InChIKey
- URXVLIVRJJNJII-UHFFFAOYSA-N
- SMILES
- C(O)(=O)CC(C1=CC=C(Cl)C=C1)CC(O)=O
- CAS DataBase Reference
- 35271-74-0(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- C378250
- Product name
- 3-(4-Chlorophenyl)glutaricAcid
- Packaging
- 250mg
- Price
- $95
- Updated
- 2021/12/16
- Product number
- C378250
- Product name
- 3-(4-Chlorophenyl)glutaricAcid
- Packaging
- 1g
- Price
- $120
- Updated
- 2021/12/16
- Product number
- C378250
- Product name
- 3-(4-Chlorophenyl)glutaricAcid
- Packaging
- 5g
- Price
- $135
- Updated
- 2021/12/16
- Product number
- C378250
- Product name
- 3-(4-Chlorophenyl)glutaricAcid
- Packaging
- 10g
- Price
- $155
- Updated
- 2021/12/16
- Product number
- FC20344
- Product name
- 3-(4-Chlorophenyl)glutaric acid
- Packaging
- 500mg
- Price
- $200
- Updated
- 2021/12/16
3-(4-Chlorophenyl)glutaric acid Chemical Properties,Usage,Production
Chemical Properties
White Solid
Uses
3-(4-Chlorophenyl)glutaric Acid (cas# 35271-74-0) is a compound useful in organic synthesis. Baclofen Impurity 1
Synthesis
19411-80-4
35271-74-0
The general procedure for the synthesis of 3-(4-chlorophenyl)glutaric acid using baclofen impurity 9 as starting material: the intermediate Π was dissolved in 420 mL of a 30 N aqueous solution of potassium hydroxide and the reaction was stirred for 2 hr at 85-90 °C. The reaction process was monitored by thin layer chromatography (TLC) and the unfolding agent was a mixture of ethyl acetate and petroleum ether (2:3, v/v). After completion of the reaction, the reaction mixture was cooled to room temperature and 400 mL of dichloromethane and 500 mL of deionized water were added sequentially. After stirring for 20 min, the organic and aqueous layers were separated and the organic layer was discarded. The aqueous layer was acidified to pH 1-2 with 6 M hydrochloric acid and the precipitated solid was subsequently filtered. The solid was washed with deionized water and dried under vacuum at 55-60°C for 5 h to give 157 g of white solid intermediate in 86.4% yield. The melting point of the intermediate was 166.5~167.3 °C.
References
[1] Patent: CN106187794, 2016, A. Location in patent: Paragraph 0023; 0028
3-(4-Chlorophenyl)glutaric acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-(4-Chlorophenyl)glutaric acid manufacturers
- Product
- 3-(4-Chlorophenyl)glutaric acid 35271-74-0
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-10-29
- Product
- 3-(4-Chlorophenyl)glutaric acid 35271-74-0
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-10
- Product
- 3-(4-Chlorophenyl)glutaric acid 35271-74-0
- Price
- US $20.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 10 tons
- Release date
- 2023-09-05