3-(4-Chlorophenyl)glutaramic acid

Product Name: 3-(4-Chlorophenyl)glutaramic acid
CAS No.: 1141-23-7
Chemical Name: 3-(4-Chlorophenyl)glutaramic acid
Synonyms: utaramic Acid;Baclofen iMpurity B;Baclofen EP Impurity B;Β-(4-Chlorophenyl)Glutarimide;3-(p-chlorophenyl)glutaramic acid;3-(4-CHLOROPHENYL)GLUTARAMIC ACID;3-(4-Chlorophenyl) Glutarmic Acid;(3RS)-5-Amino-3-(4-chlorophenyl)-5-;-(4-Chlorophenyl)glutaricacidmonoamide;3-(4-CHLOROPHENYL)GLUTARIC ACID MONOAMIDE
CBNumber: CB7127492
Molecular Formula: C11H12ClNO3
Formula Weight: 241.67
MOL File: 1141-23-7.mol

More

Less

3-(4-Chlorophenyl)glutaramic acid Property

Melting point:: 168-170°C
Boiling point:: 494.9±40.0 °C(Predicted)
Density: 1.343±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: Methanol (Slightly)
form: Solid
pka: 4.50±0.10(Predicted)
color: White
BRN: 2460842
CAS DataBase Reference: 1141-23-7(CAS DataBase Reference)

More

Less

Safety

Risk Statements: 36/37/38
Safety Statements: 26-36

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

More

Less

N-Bromosuccinimide Price

TRC

Product number: C378130
Product name: 3-(4-Chlorophenyl)glutaramicAcid
Packaging: 50g
Price: $240
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC41765
Product name: 3-(4-Chlorophenyl)glutaramic acid
Packaging: 100mg
Price: $310
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC41765
Product name: 3-(4-Chlorophenyl)glutaramic acid
Packaging: 25mg
Price: $120
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC41765
Product name: 3-(4-Chlorophenyl)glutaramic acid
Packaging: 50mg
Price: $192
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC41765
Product name: 3-(4-Chlorophenyl)glutaramic acid
Packaging: 250mg
Price: $625
Updated: 2021/12/16

More

Less

3-(4-Chlorophenyl)glutaramic acid Chemical Properties,Usage,Production

Uses

3-(4-Chlorophenyl)glutaramic acids serves as a reagent for the synthesis of heterocyclic compounds as mGlu5 antagonists for treating urinary tract disorders, migraine, and gastroesophageal reflux disease.

Synthesis

84803-46-3

1141-23-7

General procedure for the synthesis of 3-(4-chlorophenyl)glutaric acid monoamide from 3-(4-chlorophenyl)glutaric acid monoamide: Intermediate IV (120 g, 0.537 mol) was taken, aqueous sodium hydroxide solution (600 μl, 15N) was added, and the reaction was stirred for 1.5 hr at 65-70 °C. After the reaction was completed, it was cooled to room temperature and toluene (500 ml) and deionized water (700 ml) were added. The mixture was stirred for 20 min, and the organic layer was discarded after standing and layering. The pH of the aqueous layer was adjusted to 2~3 with concentrated hydrochloric acid, left to stand and filtered, and the solids were washed with water. The solid was dried under vacuum at 55~60°C for 5 hours to give 116 g of white solid intermediate V in 89.5% yield.

References

[1] Patent: CN106187794, 2016, A. Location in patent: Paragraph 0025; 0030

3-(4-Chlorophenyl)glutaramic acid Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

3-(4-Chlorophenyl)glutaramic acid Suppliers

China 122 Germany 3 India 19 Ukraine 1 United Kingdom 5 United States 20 Global 170

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11035
Advantage: 64

Maya High Purity Chemicals

Tel: +86 (573) 82222445 (0)18006601000 452520369
Fax: +86 (573) 82222643
Email: sales@maya-r.com
Country: China
ProdList: 11707
Advantage: 57

Hangzhou Yuhao Chemical Technology Co., Ltd

Tel: 0571-82693216
Fax: +86-571-82880190
Email: info@yuhaochemical.com
Country: China
ProdList: 6387
Advantage: 52

Shanghai civi chemical technology co.,Ltd

Tel: 86-21-34053660
Fax: 86-21-34053661
Email: sale@labgogo.com
Country: China
ProdList: 9865
Advantage: 52

Shanghai T&W Pharmaceutical Co., Ltd.

Tel: +86 21 61551611
Fax: +86 21 50676805
Country: China
ProdList: 9891
Advantage: 58

Shanghai Raise Chemical Technology Co.,Ltd

Tel: +86-021-50935922
Fax: +86-021-33847795
Country: China
ProdList: 7865
Advantage: 55

Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.

Tel: +86-28-85122536 85324413
Fax: +86-28-85326443
Email: market@astatech.cn
Country: China
ProdList: 8026
Advantage: 55

More

Less

View Lastest Price from 3-(4-Chlorophenyl)glutaramic acid manufacturers

RongNa Biotechnology Co.,Ltd

Product: 3-(4-Chlorophenyl)glutaramic acid 1141-23-7
Price: US $10.00/ASSAYS
Min. Order: 1ASSAYS
Purity: 99%
Supply Ability: 1 ton
Release date: 2025-08-19

Shaanxi Dideu New Materials Co. Ltd

Product: 3-(4-Chlorophenyl)glutaramic acid 1141-23-7
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000KGS
Release date: 2025-05-23

Henan Aochuang Chemical Co.,Ltd.

Product: 3-(4-Chlorophenyl)glutaramic acid 1141-23-7
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-10

1141-23-7, 3-(4-Chlorophenyl)glutaramic acidRelated Search:

Triphenylmethyl Chloride 1,3-Acetonedicarboxylic acid Glutaric acid Chlorantraniliprole tert-Butylchlorodiphenylsilane Glutaric anhydride 3-(4-Chlorophenyl)glutaric acid Baclofen impurity 6 BETA-(4-CHLOROPHENYL)GLUTARIC ANHYDRIDE Baclofen-d4 4-(4-Chlorophenyl)-2-pyrrolidinone 3-(4-CHLOROPHENYL) GLUTARIMIDE Baclofen Impurity 2 (beta-(4-Chlorophenyl)-gama-Hydroxybutyric Acid) Baclofen Impurity 3 (Mixture of Diastereomers) ETHYL 4-(4-CHLOROPHENYL)-1-(2-ETHOXY-2-OXOETHYL)-2-METHYL-6-OXO-1,4,5,6-TETRAHYDRO-3-PYRIDINECARBOXYLATE ETHYL 4-(2,4-DICHLOROPHENYL)-2-METHYL-6-OXO-1,4,5,6-TETRAHYDRO-3-PYRIDINECARBOXYLATE 3-(4-Chlorophenyl)glutaramic acid Chlorophenyl

-(4-Chlorophenyl)glutaricacidmonoamide

B-(4-CHLOROPHENYL) GLUTARIC ACID MONOAMIDE

3-(4-CHLOROPHENYL)GLUTARAMIC ACID

3-(4-CHLOROPHENYL)GLUTARIC ACID MONOAMIDE

beta-(4-Chlorophenyl)glutaric acid monoamide

3-(4-Chlorophenyl)Glutaramic Acid Monoamide

Benzenepropanoic acid, b-(2-aMino-2-oxoethyl)-4-chloro-

3-(p-chlorophenyl)glutaramic acid

5-AMino-3-(4-chlorophenyl)-5-oxopentanoic acid

Baclofen iMpurity B

4-Carbamoyl-3-(4-chlorophenyl)butanoic Acid

Baclofen EP Impurity B

Baclofen Impurity 2（Baclofen EP Impurity B）

Β-(4-Chlorophenyl)Glutarimide

(3RS)-5-Amino-3-(4-chlorophenyl)-5-

utaramic Acid

(3RS)-5-Amino-3-(4-chlorophenyl)-5-oxopentanoic acid

Benzenepropanoic acid, β-(2-amino-2-oxoethyl)-4-chloro-

Baclofen Impurity BQ: What is Baclofen Impurity B Q: What is the CAS Number of Baclofen Impurity B Q: What is the storage condition of Baclofen Impurity B Q: What are the applications of Baclofen Impurity B

β-(2-Amino-2-oxoethyl)-4-chlorobenzenepropanoic acid

beta-(2-Amino-2-oxoethyl)-4-chlorobenzenepropanoic acid

3-(4-Chlorophenyl) Glutarmic Acid

Baclofen Imp. B (EP): (3RS)-5-Amino-3-(4-chlorophenyl)- 5-oxopentanoic Acid

1141-23-7

1114-23-7

114-23-7

Organic acids