ChemicalBook > CAS DataBase List > 3-(4-Chlorophenyl)glutaramic acid

3-(4-Chlorophenyl)glutaramic acid

Product Name: 3-(4-Chlorophenyl)glutaramic acid
CAS No.: 1141-23-7
Chemical Name: 3-(4-Chlorophenyl)glutaramic acid
Synonyms: utaramic Acid;Baclofen iMpurity B;Baclofen EP Impurity B;Β-(4-Chlorophenyl)Glutarimide;3-(p-chlorophenyl)glutaramic acid;3-(4-CHLOROPHENYL)GLUTARAMIC ACID;3-(4-Chlorophenyl) Glutarmic Acid;(3RS)-5-Amino-3-(4-chlorophenyl)-5-;-(4-Chlorophenyl)glutaricacidmonoamide;3-(4-CHLOROPHENYL)GLUTARIC ACID MONOAMIDE
CBNumber: CB7127492
Molecular Formula: C11H12ClNO3
Formula Weight: 241.67
MOL File: 1141-23-7.mol

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3-(4-Chlorophenyl)glutaramic acid Property

Melting point:: 168-170°C
Boiling point:: 494.9±40.0 °C(Predicted)
Density: 1.343±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: Methanol (Slightly)
form: Solid
pka: 4.50±0.10(Predicted)
color: White
BRN: 2460842
CAS DataBase Reference: 1141-23-7(CAS DataBase Reference)

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Safety

Risk Statements: 36/37/38
Safety Statements: 26-36

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC

Product number: C378130
Product name: 3-(4-Chlorophenyl)glutaramicAcid
Packaging: 50g
Price: $240
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC41765
Product name: 3-(4-Chlorophenyl)glutaramic acid
Packaging: 100mg
Price: $310
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC41765
Product name: 3-(4-Chlorophenyl)glutaramic acid
Packaging: 25mg
Price: $120
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC41765
Product name: 3-(4-Chlorophenyl)glutaramic acid
Packaging: 50mg
Price: $192
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC41765
Product name: 3-(4-Chlorophenyl)glutaramic acid
Packaging: 250mg
Price: $625
Updated: 2021/12/16

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3-(4-Chlorophenyl)glutaramic acid Chemical Properties,Usage,Production

Uses

3-(4-Chlorophenyl)glutaramic acids serves as a reagent for the synthesis of heterocyclic compounds as mGlu5 antagonists for treating urinary tract disorders, migraine, and gastroesophageal reflux disease.

Synthesis

84803-46-3

1141-23-7

General procedure for the synthesis of 3-(4-chlorophenyl)glutaric acid monoamide from 3-(4-chlorophenyl)glutaric acid monoamide: Intermediate IV (120 g, 0.537 mol) was taken, aqueous sodium hydroxide solution (600 μl, 15N) was added, and the reaction was stirred for 1.5 hr at 65-70 °C. After the reaction was completed, it was cooled to room temperature and toluene (500 ml) and deionized water (700 ml) were added. The mixture was stirred for 20 min, and the organic layer was discarded after standing and layering. The pH of the aqueous layer was adjusted to 2~3 with concentrated hydrochloric acid, left to stand and filtered, and the solids were washed with water. The solid was dried under vacuum at 55~60°C for 5 hours to give 116 g of white solid intermediate V in 89.5% yield.

References

[1] Patent: CN106187794, 2016, A. Location in patent: Paragraph 0025; 0030

3-(4-Chlorophenyl)glutaramic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 3-(4-Chlorophenyl)glutaramic acid manufacturers

RongNa Biotechnology Co.,Ltd

Product: 3-(4-Chlorophenyl)glutaramic acid 1141-23-7
Price: US $10.00/ASSAYS
Min. Order: 1ASSAYS
Purity: 99%
Supply Ability: 1 ton
Release date: 2025-08-19

Shaanxi Dideu New Materials Co. Ltd

Product: 3-(4-Chlorophenyl)glutaramic acid 1141-23-7
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000KGS
Release date: 2025-05-23

Henan Aochuang Chemical Co.,Ltd.

Product: 3-(4-Chlorophenyl)glutaramic acid 1141-23-7
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-10

1141-23-7, 3-(4-Chlorophenyl)glutaramic acidRelated Search:

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beta-(4-Chlorophenyl)glutaric acid monoamide

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5-AMino-3-(4-chlorophenyl)-5-oxopentanoic acid

Baclofen iMpurity B

4-Carbamoyl-3-(4-chlorophenyl)butanoic Acid

Baclofen EP Impurity B

Baclofen Impurity 2（Baclofen EP Impurity B）

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utaramic Acid

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Baclofen Impurity BQ: What is Baclofen Impurity B Q: What is the CAS Number of Baclofen Impurity B Q: What is the storage condition of Baclofen Impurity B Q: What are the applications of Baclofen Impurity B

β-(2-Amino-2-oxoethyl)-4-chlorobenzenepropanoic acid

beta-(2-Amino-2-oxoethyl)-4-chlorobenzenepropanoic acid

3-(4-Chlorophenyl) Glutarmic Acid

Baclofen Imp. B (EP): (3RS)-5-Amino-3-(4-chlorophenyl)- 5-oxopentanoic Acid

1141-23-7

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114-23-7

Organic acids