2,2'-Dithiosalicylic acid
- Product Name
- 2,2'-Dithiosalicylic acid
- CAS No.
- 119-80-2
- Chemical Name
- 2,2'-Dithiosalicylic acid
- Synonyms
- DSTA;DITHIOSALICYLIC ACID;2,2'-disulfanediyldibenzoic acid;NSC 213;NSC 5346;NSC 405662;NSC 633230;AKOS AUF01570;Dithioslicylicacid;2,2'-Dithiodibenzoic
- CBNumber
- CB1420317
- Molecular Formula
- C14H10O4S2
- Formula Weight
- 306.36
- MOL File
- 119-80-2.mol
2,2'-Dithiosalicylic acid Property
- Melting point:
- 287-290 °C(lit.)
- Boiling point:
- 416.97°C (rough estimate)
- Density
- 1.4555 (rough estimate)
- vapor pressure
- 0Pa at 25℃
- refractive index
- 1.4950 (estimate)
- storage temp.
- Refrigerator
- solubility
- DMSO (Slightly), Methanol (Slightly)
- pka
- 3.02±0.36(Predicted)
- form
- Powder
- color
- Brown
- Water Solubility
- insoluble
- BRN
- 2221810
- InChIKey
- LBEMXJWGHIEXRA-UHFFFAOYSA-N
- LogP
- 1.61 at 25℃ and pH6.2-6.48
- CAS DataBase Reference
- 119-80-2(CAS DataBase Reference)
- EPA Substance Registry System
- Benzoic acid, 2,2'-dithiobis- (119-80-2)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36-24/25
- WGK Germany
- 3
- RTECS
- DG9660000
- Hazard Note
- Harmful/irritant
- TSCA
- Yes
- HS Code
- 29309070
- Toxicity
- LD50 ipr-mus: 367 mg/kg ARZNAD 21,284,71
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- PHR2590
- Product name
- Thimerosal Related Compound A
- Purity
- Pharmaceutical Secondary Standard; Certified Reference Material
- Packaging
- 100MG
- Price
- $534
- Updated
- 2024/03/01
- Product number
- 43761
- Product name
- 2,2′-Dithiodibenzoic acid
- Purity
- ≥95.0% (NT)
- Packaging
- 100g
- Price
- $53.1
- Updated
- 2024/03/01
- Product number
- 1659001
- Product name
- Thimerosal Related Compound A
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 50mg
- Price
- $1450
- Updated
- 2024/03/01
- Product number
- D1437
- Product name
- 2,2'-Dithiodibenzoic Acid
- Purity
- >96.0%(HPLC)(T)
- Packaging
- 25g
- Price
- $83
- Updated
- 2024/03/01
- Product number
- D1437
- Product name
- 2,2'-Dithiodibenzoic Acid
- Purity
- >96.0%(HPLC)(T)
- Packaging
- 100g
- Price
- $174
- Updated
- 2024/03/01
2,2'-Dithiosalicylic acid Chemical Properties,Usage,Production
Chemical Properties
brown powder
Uses
2,2'-Dithiosalicylic acid is an organosulfur compound produced from dibenzothiophene metabolites that is in turn biodegraded into transient metabolites such as benzoic acid.It is used in the preparation of a new class of anti-HIV-1 agents.
Uses
2,2′-Dithiodibenzoic acid may be used for the preparation of novel anionic heptadecanuclear silver(I) cluster, by the reaction with equivalent molar silver oxide under ultrasonic conditions at 50°C. It may be used for the preparation of polyamides containing a disulfide bond in their main chain.
General Description
2,2′-Dithiodibenzoic acid is an sulfhydryl modifying reagent. 2,2′-Dithiodibenzoic acid on cocrystallization with imidazole or 4-methylimidazole affords bis(imidazolium) 2,2′-dithiodibenzoate and 4-methylimidazolium 2-[(2-carboxyphenyl)disulfanyl]benzoate organic salt, respectively. It also cocrystallizes with isonicotinohydrazide from methanol solution to afford the 1:2 cocrystal, 2,2′-dithiodibenzoic acid-isonicotinohydrazide.
Safety Profile
Poison by intraperitoneal route.When heated to decomposition it emits toxic vapors ofSOx.
Synthesis
A preparation method of 2,2'-dithiosalicylic acid is as follows: using anthranilic acid as raw material and performing a diazotization reaction with sodium nitrite and hydrochloric acid at 0 to 10°C to obtain a diazo liquid. The liquid reacts with liquid sulfur dioxide for 0.5 to 3 hours in the presence of a catalyst and a cocatalyst at -20~~-10°C and then is kept at 80~100°C for 0.5~2 hours, cooled, and filtered to obtain 2,2'-Dithiosalicylic acid.
2,2'-Dithiosalicylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2,2'-Dithiosalicylic acid manufacturers
- Product
- 2,2'-Dithiosalicylic acid 119-80-2
- Price
- US $50.00/kg
- Min. Order
- 1kg
- Purity
- 99
- Supply Ability
- 5000
- Release date
- 2024-12-03
- Product
- 2,2'-Dithiosalicylic acid (DSTA) 119-80-2
- Price
- US $5.00/KG
- Min. Order
- 1KG
- Purity
- ≥99%
- Supply Ability
- 5000mt/year
- Release date
- 2023-07-17
- Product
- 2,2'-Dithiosalicylic acid (DSTA) 119-80-2
- Price
- US $30.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 2000kg
- Release date
- 2024-05-16