2,2'-Dithiosalicylic acid

Product Name: 2,2'-Dithiosalicylic acid
CAS No.: 119-80-2
Chemical Name: 2,2'-Dithiosalicylic acid
Synonyms: DSTA;DITHIOSALICYLIC ACID;2,2'-disulfanediyldibenzoic acid;NSC 213;NSC 5346;NSC 405662;NSC 633230;AKOS AUF01570;Dithioslicylicacid;2,2'-Dithiodibenzoic
CBNumber: CB1420317
Molecular Formula: C14H10O4S2
Formula Weight: 306.36
MOL File: 119-80-2.mol

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2,2'-Dithiosalicylic acid Property

Melting point:: 287-290 °C(lit.)
Boiling point:: 416.97°C (rough estimate)
Density: 1.4555 (rough estimate)
vapor pressure: 0Pa at 25℃
refractive index: 1.4950 (estimate)
storage temp.: Refrigerator
solubility: DMSO (Slightly), Methanol (Slightly)
form: Powder
pka: 3.02±0.36(Predicted)
color: Brown
Water Solubility: insoluble
BRN: 2221810
InChIKey: LBEMXJWGHIEXRA-UHFFFAOYSA-N
LogP: 1.61 at 25℃ and pH6.2-6.48
CAS DataBase Reference: 119-80-2(CAS DataBase Reference)
EPA Substance Registry System: Benzoic acid, 2,2'-dithiobis- (119-80-2)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-24/25
WGK Germany: 3
RTECS: DG9660000
Hazard Note: Harmful/irritant
TSCA: Yes
HS Code: 29309070
Toxicity: LD50 ipr-mus: 367 mg/kg ARZNAD 21,284,71

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHR2590
Product name: Thimerosal Related Compound A
Purity: Pharmaceutical Secondary Standard; Certified Reference Material
Packaging: 100MG
Price: $534
Updated: 2024/03/01

Sigma-Aldrich

Product number: 43761
Product name: 2,2′-Dithiodibenzoic acid
Purity: ≥95.0% (NT)
Packaging: 100g
Price: $53.1
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1659001
Product name: Thimerosal Related Compound A
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 50mg
Price: $1450
Updated: 2024/03/01

TCI Chemical

Product number: D1437
Product name: 2,2'-Dithiodibenzoic Acid
Purity: >96.0%(HPLC)(T)
Packaging: 25g
Price: $83
Updated: 2024/03/01

TCI Chemical

Product number: D1437
Product name: 2,2'-Dithiodibenzoic Acid
Purity: >96.0%(HPLC)(T)
Packaging: 100g
Price: $174
Updated: 2024/03/01

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2,2'-Dithiosalicylic acid Chemical Properties,Usage,Production

Chemical Properties

brown powder

Uses

2,2'-Dithiosalicylic acid is an organosulfur compound produced from dibenzothiophene metabolites that is in turn biodegraded into transient metabolites such as benzoic acid.It is used in the preparation of a new class of anti-HIV-1 agents.

Uses

2,2′-Dithiodibenzoic acid may be used for the preparation of novel anionic heptadecanuclear silver(I) cluster, by the reaction with equivalent molar silver oxide under ultrasonic conditions at 50°C. It may be used for the preparation of polyamides containing a disulfide bond in their main chain.

General Description

2,2′-Dithiodibenzoic acid is an sulfhydryl modifying reagent. 2,2′-Dithiodibenzoic acid on cocrystallization with imidazole or 4-methylimidazole affords bis(imidazolium) 2,2′-dithiodibenzoate and 4-methylimidazolium 2-[(2-carboxyphenyl)disulfanyl]benzoate organic salt, respectively. It also cocrystallizes with isonicotinohydrazide from methanol solution to afford the 1:2 cocrystal, 2,2′-dithiodibenzoic acid-isonicotinohydrazide.

Safety Profile

Poison by intraperitoneal route.When heated to decomposition it emits toxic vapors ofSOx.

Synthesis

A preparation method of 2,2'-dithiosalicylic acid is as follows: using anthranilic acid as raw material and performing a diazotization reaction with sodium nitrite and hydrochloric acid at 0 to 10°C to obtain a diazo liquid. The liquid reacts with liquid sulfur dioxide for 0.5 to 3 hours in the presence of a catalyst and a cocatalyst at -20~~-10°C and then is kept at 80~100°C for 0.5~2 hours, cooled, and filtered to obtain 2,2'-Dithiosalicylic acid.

2,2'-Dithiosalicylic acid Preparation Products And Raw materials

Raw materials

Anthranilic acid

Preparation Products

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2,2'-Dithiosalicylic acid Suppliers

Americas 1 Belgium 2 Canada 2 China 371 Czech Republic 1 Europe 4 France 2 Germany 9 India 28 Japan 5 Slovakia 1 South Korea 2 Switzerland 4 The Netherlands 2 Ukraine 2 United Kingdom 18 United States 51 Global 505

Dongying Sifang Litong New Material Co. LTD

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INTATRADE GmbH

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3B Pharmachem (Wuhan) International Co.,Ltd.

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Alfa Aesar

Tel: 400-6106006
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View Lastest Price from 2,2'-Dithiosalicylic acid manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 2,2'-Dithiosalicylic acid 119-80-2
Price: US $0.00/KG
Min. Order: 1KG
Purity: 96.0%
Supply Ability: 1000kg/month
Release date: 2021-07-27

Jinan Finer Chemical Co., Ltd

Product: 2,2'-Dithiosalicylic acid (DSTA) 119-80-2
Price: US $5.00/KG
Min. Order: 1KG
Purity: ≥99%
Supply Ability: 5000mt/year
Release date: 2023-07-17

hebei hongtan Biotechnology Co., Ltd

Product: 2,2'-Dithiosalicylic acid (DSTA) 119-80-2
Price: US $30.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 2000kg
Release date: 2024-05-16

119-80-2, 2,2'-Dithiosalicylic acidRelated Search:

Dilauryl thiodipropionate Diphenylthiocarbazide TEREPHTHALIC DIHYDRAZIDE Terephthalic acid Folic acid Thiobenzoic acid Ethyl 2-(Chlorosulfonyl)acetate Citric acid Ascoric Acid Zinc Dialkyl Dithio Phosphate(ZDDP) DIPHENYL DISULFIDE Thiosalicylic acid Salicylic acid 2,2'-Dithiobis(3-methylbenzoic acid) dimethyl 2,2'-dithiobisbenzoate 2,2'-DITHIOBIS(6-FLUOROBENZOIC ACID) 2,2'-Dithiosalicylic acid 2,2'-DITHIOSALICYLIC ACID, DISODIUM SALT,2,2'-DITHIOSALICYLIC ACID, DISODIUM SALT

2,2'-Dithiodibenzoic acid >=95.0% (NT)

2,2’-dithiobis(benzoicacid)

2,2’-dithiobis-benzoicaci

Thimerosal Related Compound A

DSTA

2,2'-DITHIOSALICYLIC ACID, TECH., 85%

2-Hydroxybenzenecarbothioic acid

2-Carboxyphenyl disulfide, Bis(2-carboxyphenyl) disulfide, Dithiosalicylic acid

2,2'-DITHIOBENZOCI ACID

2,2 -DITHIOSALICYCLIC ACID

2,2 '-dithio-dibenzoate

2-Hydroxybenzenethionothiolic acid

o-Hydroxydithiobenzoic acid

2'-Dithiodibenzoic acid

2,2'-Dithiodibenzoic

Benzoic acid, 2,2-dithiobis-

2,2'-Dithiosalicylic acid 82%

Dithioslicylicacid

DL-Tryptophan, 5-methoxy-

NSC 405662

Bis(o-carboxylphenyl)disulfide

2,2'-Dithiosalicylic acid,98%

NSC 213

NSC 5346

NSC 633230

o,o'-Dithiodibenzoic acid

2,2'-DITHIODIBENZOIC ACID FOR SYNTHESIS

DTSA)2,2′-Dithiodiben

2,2'-Dithiosalicylic acid(DTSA)

2,2'-disulfanediyldibenzoic acid

2,2'-Disulphanediyldibenzoic acid 82%

2-[(2-carboxylatophenyl)disulfanyl]benzoate

2,2’-dithiodibenzoesaeure

2,2’-dithiodi-benzoicaci

bis(o-carboxyphenyl)disulfide

AKOS AUF01570

2-(2-CARBOXYPHENYL)DISULFANYLBENZOIC ACID

2,2'-DITHIOSALICYLIC ACID

2,2'-DITHIODIBENZOIC ACID

2,2-DITHIODIBENZOIC ACID

2,2'-DITHIOBENZOIC ACID

2,2-DITHIOBENZOIC ACID

2-CARBOXYPHENYL DISULFIDE

BIS(2-CARBOXYPHENYL) DISULFIDE

DITHIOSALICYLIC ACID

DIPHENYL DISULFIDE-2,2'-DICARBOXYLIC ACID

di(2-carboxyphenyl) disulphide

2-Carboxyphenyl disulfide 2,2'-Dithiodibenzoic Acid

2,2'-Dithiosalicy acid

2,2-Dithiodibenzoic acid(Technical)

2,2'-Dithiodibenzoic Acid &gt

2,2'-Dithiosalicylic acid (DSTA)

Thimerosal Related Compound A (2,2''-Disulfanediyldibenzoic acid) (1659001)

2,2'-Dithiosalicylic acid

2,2'-Dithiodibenzoic acid

2,2'- dithiobenzoic acid

2,2'-Disulfanediyldibenzoic acid

Axitinib Impurity N24