ChemicalBook > CAS DataBase List > 2,2'-Dithiosalicylic acid

2,2'-Dithiosalicylic acid

Product Name
2,2'-Dithiosalicylic acid
CAS No.
119-80-2
Chemical Name
2,2'-Dithiosalicylic acid
Synonyms
DSTA;DITHIOSALICYLIC ACID;2,2'-disulfanediyldibenzoic acid;NSC 213;NSC 5346;NSC 405662;NSC 633230;AKOS AUF01570;Dithioslicylicacid;2,2'-Dithiodibenzoic
CBNumber
CB1420317
Molecular Formula
C14H10O4S2
Formula Weight
306.36
MOL File
119-80-2.mol
More
Less

2,2'-Dithiosalicylic acid Property

Melting point:
287-290 °C(lit.)
Boiling point:
416.97°C (rough estimate)
Density 
1.4555 (rough estimate)
vapor pressure 
0Pa at 25℃
refractive index 
1.4950 (estimate)
storage temp. 
Refrigerator
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Powder
pka
3.02±0.36(Predicted)
color 
Brown
Water Solubility 
insoluble
BRN 
2221810
InChIKey
LBEMXJWGHIEXRA-UHFFFAOYSA-N
LogP
1.61 at 25℃ and pH6.2-6.48
CAS DataBase Reference
119-80-2(CAS DataBase Reference)
EPA Substance Registry System
Benzoic acid, 2,2'-dithiobis- (119-80-2)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-24/25
WGK Germany 
3
RTECS 
DG9660000
Hazard Note 
Harmful/irritant
TSCA 
Yes
HS Code 
29309070
Toxicity
LD50 ipr-mus: 367 mg/kg ARZNAD 21,284,71
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR2590
Product name
Thimerosal Related Compound A
Purity
Pharmaceutical Secondary Standard; Certified Reference Material
Packaging
100MG
Price
$534
Updated
2024/03/01
Sigma-Aldrich
Product number
43761
Product name
2,2′-Dithiodibenzoic acid
Purity
≥95.0% (NT)
Packaging
100g
Price
$53.1
Updated
2024/03/01
Sigma-Aldrich
Product number
1659001
Product name
Thimerosal Related Compound A
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
50mg
Price
$1450
Updated
2024/03/01
TCI Chemical
Product number
D1437
Product name
2,2'-Dithiodibenzoic Acid
Purity
>96.0%(HPLC)(T)
Packaging
25g
Price
$83
Updated
2024/03/01
TCI Chemical
Product number
D1437
Product name
2,2'-Dithiodibenzoic Acid
Purity
>96.0%(HPLC)(T)
Packaging
100g
Price
$174
Updated
2024/03/01
More
Less

2,2'-Dithiosalicylic acid Chemical Properties,Usage,Production

Chemical Properties

brown powder

Uses

2,2'-Dithiosalicylic acid is an organosulfur compound produced from dibenzothiophene metabolites that is in turn biodegraded into transient metabolites such as benzoic acid.It is used in the preparation of a new class of anti-HIV-1 agents.

Uses

2,2′-Dithiodibenzoic acid may be used for the preparation of novel anionic heptadecanuclear silver(I) cluster, by the reaction with equivalent molar silver oxide under ultrasonic conditions at 50°C. It may be used for the preparation of polyamides containing a disulfide bond in their main chain.

General Description

2,2′-Dithiodibenzoic acid is an sulfhydryl modifying reagent. 2,2′-Dithiodibenzoic acid on cocrystallization with imidazole or 4-methylimidazole affords bis(imidazolium) 2,2′-dithiodibenzoate and 4-methylimidazolium 2-[(2-carboxyphenyl)disulfanyl]benzoate organic salt, respectively. It also cocrystallizes with isonicotinohydrazide from methanol solution to afford the 1:2 cocrystal, 2,2′-dithiodibenzoic acid-isonicotinohydrazide.

Safety Profile

Poison by intraperitoneal route.When heated to decomposition it emits toxic vapors ofSOx.

Synthesis

A preparation method of 2,2'-dithiosalicylic acid is as follows: using anthranilic acid as raw material and performing a diazotization reaction with sodium nitrite and hydrochloric acid at 0 to 10°C to obtain a diazo liquid. The liquid reacts with liquid sulfur dioxide for 0.5 to 3 hours in the presence of a catalyst and a cocatalyst at -20~~-10°C and then is kept at 80~100°C for 0.5~2 hours, cooled, and filtered to obtain 2,2'-Dithiosalicylic acid.

2,2'-Dithiosalicylic acid Preparation Products And Raw materials

Raw materials

Anthranilic acid

Preparation Products

More
Less

2,2'-Dithiosalicylic acid Suppliers

Americas 1 Belgium 2 Canada 2 China 368 Czech Republic 1 Europe 4 France 2 Germany 9 India 27 Japan 5 Slovakia 1 South Korea 2 Switzerland 4 The Netherlands 2 Ukraine 2 United Kingdom 18 United States 52 Global 502
Dongying Sifang Litong New Material Co. LTD
Tel
17861826421
Email
dysflt@126.com
Country
China
ProdList
276
Advantage
58
Beijing Holiyang Chemical Co. Ltd.
Tel
13718199399
Fax
QQ : 206661479
Email
holiyangchem@163.com
Country
China
ProdList
3387
Advantage
56
Wisdom Drugs Co., Ltd.
Tel
18261161868
Email
527536256@qq.com
Country
China
ProdList
314
Advantage
58
Hubei Keyijia Chemical Co., Ltd.
Tel
15629167229
Email
1796273473@qq.com
Country
China
ProdList
428
Advantage
58
Wuhan Rongcan Biotechnology Co., Ltd
Tel
18327024450
Fax
183-27024450
Email
2130026275@qq.com
Country
China
ProdList
4590
Advantage
58
Wuhan Qixinhui Technology Co., Ltd
Tel
027-87002654 18062710658
Email
554831559@qq.com
Country
China
ProdList
934
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40240
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2341
Advantage
56
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18217
Advantage
66
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9816
Advantage
59
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
18089
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
Country
China
ProdList
42982
Advantage
64
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8849
Advantage
52
Shandong Xiya Chemical Co., Ltd
Tel
13355009207 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18739
Advantage
57
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12990
Advantage
57
BEST-REAGENT
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11726
Advantage
57
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7815
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14443
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9823
Advantage
79
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11714
Advantage
57
Beijing Taiya Jie Technology Development Co., Ltd.
Tel
021-33690831-8001 13552411790
Fax
021-33690831
Email
postmaster@tyjchem.cn
Country
China
ProdList
1542
Advantage
55
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9872
Advantage
52
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17779
Advantage
75
Beijing innoChem Science & Technology Co.,Ltd.
Tel
400-810-7969 010-59572699
Fax
010-59572688
Email
ningzi.li@inno-chem.com.cn
Country
China
ProdList
6139
Advantage
55
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66099280 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19918
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18216
Advantage
56
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
18521735133 18521732826;
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25014
Advantage
65
Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.
Tel
+86-28-85122536 85324413
Fax
+86-28-85326443
Email
market@astatech.cn
Country
China
ProdList
8033
Advantage
55
Zouping Mingxing Chemical Co.,Ltd.
Tel
86-13605431940 13605431940
Fax
0086-0543-2240079
Email
zpmxchemical@126.com
Country
China
ProdList
2002
Advantage
62
Quzhou Juhua Friendship Co., Ltd
Tel
0570-3066667
Fax
0570-3063388
Country
China
ProdList
3933
Advantage
58
Shanghai BeiZhuo Biotech Co., Ltd.
Tel
021-61119791,13386096464
Fax
021-50190009
Email
bzswkf@foxmail.com
Country
China
ProdList
3924
Advantage
50
Hubei XinyuanShun Chemical Co., Ltd.
Tel
13971561712, 13995564702, 027-50664929
Fax
027-50664927
Email
hbeixys2001@163.com
Country
China
ProdList
3123
Advantage
55
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9986
Advantage
55
Bide Pharmatech Ltd.
Tel
400-1647117 15221909166
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41438
Advantage
60
Chemwill Asia Co.,Ltd.
Tel
86-21-51086038
Fax
86-21-51861608
Country
China
ProdList
2931
Advantage
58
Shanghai DiBai Chemicals Co., Ltd.
Tel
021-54359730 400-008-9730
Fax
021-54353864
Email
info@chemxyz.com
Country
China
ProdList
3993
Advantage
60
Mei Lan Industrial (Shanghai) Co., Ltd.
Tel
021-58958189
Fax
021-58957967
Email
wouchina@126.com
Country
China
ProdList
2671
Advantage
55
Shanghai Worldyang Chemical Co.,Ltd.
Tel
021-021-56795766
Fax
+86-21-56795266
Email
sales@worldyachem.com
Country
China
ProdList
9352
Advantage
58
Shanghai ideal Industrial Co., Ltd.
Tel
021-58957966 18930537195
Fax
021-60899437
Email
wouchina@126.com
Country
China
ProdList
3033
Advantage
58
Chengdu HuaXia Chemical Reagent Co. Ltd
Tel
400-1166-196 13458535857
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
13359
Advantage
58
GuangTuo Chemical (Shanghai) Co., Ltd.
Tel
021-60899189-8001 18918189673
Fax
021-60899304
Email
gtchem@126.com
Country
China
ProdList
2661
Advantage
58
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15185
Advantage
58
Credit-Chem Co., Ltd.
Tel
400-821-5857 021-64326257
Fax
021-64393586 QQ;2798200800
Email
credit-chem@foxmail.com
Country
China
ProdList
5223
Advantage
58
Wuhan Dahua Pharmaceutical Co., Ltd.
Tel
027-59262863 13277907145 3091977954
Fax
027-59420980
Country
China
ProdList
4951
Advantage
58
More
Less

View Lastest Price from 2,2'-Dithiosalicylic acid manufacturers

hebei hongtan Biotechnology Co., Ltd
Product
2,2'-Dithiosalicylic acid (DSTA) 119-80-2
Price
US $30.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
2000kg
Release date
2024-05-16
Jinan Finer Chemical Co., Ltd
Product
2,2'-Dithiosalicylic acid (DSTA) 119-80-2
Price
US $5.00/KG
Min. Order
1KG
Purity
≥99%
Supply Ability
5000mt/year
Release date
2023-07-17
Hebei Kingfiner Technology Development Co.Ltd
Product
2,2'-Dithiosalicylic acid 119-80-2
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
500000kg
Release date
2024-05-15

119-80-2, 2,2'-Dithiosalicylic acidRelated Search:

Dilauryl thiodipropionate Diphenylthiocarbazide TEREPHTHALIC DIHYDRAZIDE Terephthalic acid Folic acid Thiobenzoic acid Ethyl 2-(Chlorosulfonyl)acetate Citric acid Ascoric Acid Zinc Dialkyl Dithio Phosphate(ZDDP) DIPHENYL DISULFIDE Thiosalicylic acid Salicylic acid 2,2'-Dithiobis(3-methylbenzoic acid) dimethyl 2,2'-dithiobisbenzoate 2,2'-DITHIOBIS(6-FLUOROBENZOIC ACID) 2,2'-Dithiosalicylic acid 2,2'-DITHIOSALICYLIC ACID, DISODIUM SALT,2,2'-DITHIOSALICYLIC ACID, DISODIUM SALT

  • 2,2'-Dithiodibenzoic acid >=95.0% (NT)
  • 2,2’-dithiobis(benzoicacid)
  • 2,2’-dithiobis-benzoicaci
  • Thimerosal Related Compound A
  • DSTA
  • 2,2'-DITHIOSALICYLIC ACID, TECH., 85%
  • 2-Hydroxybenzenecarbothioic acid
  • 2-Carboxyphenyl disulfide, Bis(2-carboxyphenyl) disulfide, Dithiosalicylic acid
  • 2,2'-DITHIOBENZOCI ACID
  • 2,2 -DITHIOSALICYCLIC ACID
  • 2,2 '-dithio-dibenzoate
  • 2-Hydroxybenzenethionothiolic acid
  • o-Hydroxydithiobenzoic acid
  • 2'-Dithiodibenzoic acid
  • 2,2'-Dithiodibenzoic
  • Benzoic acid, 2,2-dithiobis-
  • 2,2'-Dithiosalicylic acid 82%
  • Dithioslicylicacid
  • DL-Tryptophan, 5-methoxy-
  • NSC 405662
  • Bis(o-carboxylphenyl)disulfide
  • 2,2'-Dithiosalicylic acid,98%
  • NSC 213
  • NSC 5346
  • NSC 633230
  • o,o'-Dithiodibenzoic acid
  • 2,2'-DITHIODIBENZOIC ACID FOR SYNTHESIS
  • DTSA)2,2′-Dithiodiben
  • 2,2'-Dithiosalicylic acid(DTSA)
  • 2,2'-disulfanediyldibenzoic acid
  • 2,2'-Disulphanediyldibenzoic acid 82%
  • 2-[(2-carboxylatophenyl)disulfanyl]benzoate
  • 2,2’-dithiodibenzoesaeure
  • 2,2’-dithiodi-benzoicaci
  • bis(o-carboxyphenyl)disulfide
  • AKOS AUF01570
  • 2-(2-CARBOXYPHENYL)DISULFANYLBENZOIC ACID
  • 2,2'-DITHIOSALICYLIC ACID
  • 2,2'-DITHIODIBENZOIC ACID
  • 2,2-DITHIODIBENZOIC ACID
  • 2,2'-DITHIOBENZOIC ACID
  • 2,2-DITHIOBENZOIC ACID
  • 2-CARBOXYPHENYL DISULFIDE
  • BIS(2-CARBOXYPHENYL) DISULFIDE
  • DITHIOSALICYLIC ACID
  • DIPHENYL DISULFIDE-2,2'-DICARBOXYLIC ACID
  • di(2-carboxyphenyl) disulphide
  • 2-Carboxyphenyl disulfide 2,2'-Dithiodibenzoic Acid
  • 2,2'-Dithiosalicy acid
  • 2,2-Dithiodibenzoic acid(Technical)
  • 2,2'-Dithiodibenzoic Acid &gt
  • 2,2'-Dithiosalicylic acid (DSTA)
  • Thimerosal Related Compound A (2,2''-Disulfanediyldibenzoic acid) (1659001)
  • 2,2'-Dithiosalicylic acid
  • 2,2'-Dithiodibenzoic acid
  • 119-80-2
  • 119-60-7
  • 118-80-2