2-PYRIDYLTHIOUREA

Product Name: 2-PYRIDYLTHIOUREA
CAS No.: 14294-11-2
Chemical Name: 2-PYRIDYLTHIOUREA
Synonyms: 2-PYRIDYLTHIOUREA;AKOS BBS-00007311;N-(2-Pyridyl)thiourea;N-PYRIDIN-2-YLTHIOUREA;1-PYRIDIN-2-YLTHIOUREA;N-2-Pyridinyl-Thiourea;Thiourea,N-2-pyridinyl-;1-(2-PYRIDYL)-2-THIOUREA;N-(2-Pyridyl)thiourea, 98%;1-(Pyridin-2-yl)thiourea 98%
CBNumber: CB1445909
Molecular Formula: C6H7N3S
Formula Weight: 153.2
MOL File: 14294-11-2.mol

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2-PYRIDYLTHIOUREA Property

Melting point:: 148-150°C
Boiling point:: 298.7±32.0 °C(Predicted)
Density: 1.382±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
form: powder to crystal
pka: 12.00±0.70(Predicted)
color: White to Light yellow
BRN: 117849
InChI: InChI=1S/C6H7N3S/c7-6(10)9-5-3-1-2-4-8-5/h1-4H,(H3,7,8,9,10)
InChIKey: SLUHLANJIVXTRQ-UHFFFAOYSA-N
SMILES: N(C1=NC=CC=C1)C(N)=S
CAS DataBase Reference: 14294-11-2(CAS DataBase Reference)

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Safety

Risk Statements: 36/37/38
Safety Statements: 26-36/37/39
RIDADR: 2811
HazardClass: 6.1
PackingGroup: III
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical

Product number: P2272
Product name: (2-Pyridyl)thiourea
Purity: >98.0%(HPLC)(T)
Packaging: 5g
Price: $124
Updated: 2025/07/31

TCI Chemical

Product number: P2272
Product name: (2-Pyridyl)thiourea
Purity: >98.0%(HPLC)(T)
Packaging: 25g
Price: $421
Updated: 2025/07/31

TRC

Product number: P992135
Product name: 2-Pyridylthiourea
Packaging: 1g
Price: $65
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0016674
Product name: 2-PYRIDYLTHIOUREA
Purity: 95.00%
Packaging: 1G
Price: $133.35
Updated: 2021/12/16

Matrix Scientific

Product number: 056823
Product name: 1-(2-Pyridyl)-2-thiourea
Purity: 97%
Packaging: 5g
Price: $52
Updated: 2021/12/16

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2-PYRIDYLTHIOUREA Chemical Properties,Usage,Production

Uses

2-Pyridylthiourea is an intermediate used to prepare disubstituted thiazoles as potential antibacterial and antiinflammatory agents via condensation of phenacyl bromide with thioureas and thiosemicarbazones. It is also used in the synthesis of 2-amino-5-(thioaryl)thiazoles as potent and selective Itk inhibitors.

Synthesis

4921-86-2

14294-11-2

The general procedure for the synthesis of 1-(2-pyridyl)thiourea from 1-benzoyl-3-(2-pyridyl)-2-thiourea was as follows: N-(pyridin-2-ylthiocarbonyl)benzamide (2.3 g, 8.95 mmol) was suspended in a 10% aqueous NaOH solution (10.4 mL, 26 mmol) and stirred for 10 min at room temperature, then heated to reflux to continue the reaction for 10 minutes. Upon completion of the reaction, the mixture was cooled to 0 °C, diluted with 100 mL of water and subsequently extracted with ethyl acetate (3 × 150 mL). The organic phases were combined, dried with anhydrous magnesium sulfate, filtered and concentrated to give the crude product 1-(2-pyridyl)thiourea (1.2 g). Mass spectrometry (electrospray ionization) m/z (M+H) confirmed the product.

References

[1] Synthesis, 1988, # 6, p. 456 - 459
[2] Bioorganic and Medicinal Chemistry Letters, 2006, vol. 16, # 14, p. 3706 - 3712
[3] Bioorganic and Medicinal Chemistry Letters, 2008, vol. 18, # 2, p. 634 - 639
[4] Journal of the Chemical Society, 1955, p. 803
[5] Journal of Organic Chemistry USSR (English Translation), 1991, vol. 27, # 1.2, p. 177 - 182

2-PYRIDYLTHIOUREA Preparation Products And Raw materials

Raw materials

Preparation Products

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2-PYRIDYLTHIOUREA Suppliers

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View Lastest Price from 2-PYRIDYLTHIOUREA manufacturers

Career Henan Chemical Co

Product: 2-PYRIDYLTHIOUREA 14294-11-2
Price: US $500.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1ton
Release date: 2018-08-04

14294-11-2, 2-PYRIDYLTHIOUREARelated Search:

2-PYRIDYLTHIOUREA 1-PHENYL-3-(2-PYRIDYL)-2-THIOUREA N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphate 3-PYRIDYLTHIOUREA, 98+%,3-PYRIDYLTHIOUREA 4-PYRIDYLTHIOUREA 1-BENZOYL-3-(2-PYRIDYL)-2-THIOUREA 1H-IMIDAZO[4,5-B]PYRIDINE-2-THIOL (6-METHYL-PYRIDIN-2-YL)-THIOUREA METHYL 3-([(2-PYRIDINYLAMINO)CARBOTHIOYL]AMINO)-2-THIOPHENECARBOXYLATE TIMTEC-BB SBB000741 N-ALLYL-N'-PYRIDIN-2-YLTHIOUREA AURORA KA-6689 N-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]THIOUREA N-(((3-CHLORO-5-(TRIFLUOROMETHYL)(2-PYRIDYL))AMINO)THIOXOMETHYL)BENZAMIDE 1-(4-BROMOPHENYL)-2-THIOXO-1,2,3,4-TETRAHYDROPYRIDO[2,3-D]PYRIMIDIN-4-ONE BUTTPARK 78\40-86 BUTTPARK 78\40-87 BUTTPARK 77\40-81

AKOS BBS-00007311

1-(2-PYRIDYL)-2-THIOUREA

1-PYRIDIN-2-YLTHIOUREA

2-PYRIDYLTHIOUREA

N-PYRIDIN-2-YLTHIOUREA

N-(2-Pyridyl)thiourea, 98%

Thiourea,N-2-pyridinyl-

N-2-Pyridinyl-Thiourea

1-(Pyridin-2-yl)thiourea 98%

N-(2-Pyridyl)thiourea

14294-11-2

Pyridines