ChemicalBook > CAS DataBase List > (Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
(Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
- Product Name
- (Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
- CAS No.
- 2093243-16-2
- Chemical Name
- (Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
- Synonyms
- Nintedanib-013-Z;Nidanibu Impurity 8;Nintedanib impurities11;(Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate;Nintedanib impurity 12/Methyl (Z)-3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate;1H-Indole-6-carboxylic acid, 2,3-dihydro-3-(hydroxyphenylmethylene)-2-oxo-, methyl ester, (3Z)-
- CBNumber
- CB14656048
- Molecular Formula
- C17H13NO4
- Formula Weight
- 295.29
- MOL File
- 2093243-16-2.mol
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(Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate Property
- Melting point:
- >215°C (dec.)
- Boiling point:
- 536.9±50.0 °C(Predicted)
- Density
- 1.357±0.06 g/cm3(Predicted)
- storage temp.
- Hygroscopic, -20°C Freezer, Under inert atmosphere
- solubility
- DMSO (Slightly), Methanol (Slightly, Heated)
- form
- Solid
- pka
- 4.50±1.00(Predicted)
- color
- Yellow to Dark Yellow
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N-Bromosuccinimide Price
TRC
- Product number
- M323629
- Product name
- (Z)-Methyl3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
- Packaging
- 50mg
- Price
- $235
- Updated
- 2021/12/16
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(Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate Chemical Properties,Usage,Production
Uses
(Z)-Methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate is a useful intermediate for the preparation of nintedanib esylate. Nintedanib is a drug for the treatment of idiopathic pulmonary fibrosis.
(Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
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