ChemicalBook > CAS DataBase List > Roxatidine

Roxatidine

Product Name
Roxatidine
CAS No.
78273-80-0
Chemical Name
Roxatidine
Synonyms
ROXATIDINE;desacetyl-TZU-0460;Roxatidine USP/EP/BP;RoxatidineAcetateHclBase;Roxatidine in acetonitrile;ROXATIDINE ENTERPRISE STANDARD;ROXATIDINE(SUBJECTTOPATENTFREE);Benzaldehyde,5-methoxy-7-nitro-;n-{3-[3-(1-piperidinylmethyl)phenoxy]propyl}hydroxyacetamide;2-Hydroxy-N-[3-[m-(piperidinomethyl)phenoxy]propyl]acetamide
CBNumber
CB1472068
Molecular Formula
C17H26N2O3
Formula Weight
306.4
MOL File
78273-80-0.mol
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Roxatidine Property

Melting point:
59-60 °C
Boiling point:
524.3±45.0 °C(Predicted)
Density 
1.137±0.06 g/cm3(Predicted)
storage temp. 
-20°
solubility 
Soluble in DMSO (up to 25 mg/ml).
pka
13.34±0.10(Predicted)
form 
oil
color 
Colorless to pale yellow
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
CAS DataBase Reference
78273-80-0(CAS DataBase Reference)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0005304
Product name
ROXATIDINE
Purity
95.00%
Packaging
5MG
Price
$504.65
Updated
2021/12/16
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Roxatidine Chemical Properties,Usage,Production

Description

Roxatidine (78273-80-0) is a novel histamine H2 receptor antagonist.1?Suppresses inflammatory responses via inhibition of NFκB and p38 MAPK activation in LPS-induced RAW 264.7 macrophages.2?Clinically useful agent for prevention and healing of gastric and duodenal ulcers and bleeding.3?Attenuates degradation of extracellular matrix in osteoarthritis models by inactivating the NFkB pathway.4

Uses

Anti-ulcerative.

References

1) Mills and Wood (1989),?The pharmacology of histamine H2-receptor antagonists; Methods Find. Exp. Clin. Pharmacol., 11 Suppl. 1?87 2) Cho?et al. (2011), Roxatidine suppresses inflammatory responses via inhibition of NF-κB and p38 MAPK activation in LPS-induced RAW 264.7 macrophages; J. Cell. Biochem.,?112?3648 3) Imaeda?et al.?(2011),?Effect of lansoprazole versus roxatidine on prevention of bleeding and promotion of ulcer healing after endoscopic submucosal dissection for superficial gastric neoplasia; J. Gastroenterol.,?46?1267 4) Ze?et al. (2017),?Roxatidine Attenuates Degradation of Extracellular Matrix;?Biomed. Pharmacother.,?95?1156

Roxatidine Preparation Products And Raw materials

Raw materials

Preparation Products

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Roxatidine Suppliers

China 70 Europe 2 Germany 1 India 2 United Kingdom 3 United States 13 Global 91
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View Lastest Price from Roxatidine manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Roxatidine 78273-80-0
Price
US $1.00-1.00/Kg/Bag
Min. Order
1g
Purity
99%
Supply Ability
50tons
Release date
2020-04-30
Hebei Guanlang Biotechnology Co., Ltd.
Product
Roxatidine 78273-80-0
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2022-10-18
Career Henan Chemical Co
Product
Roxatidine 78273-80-0
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200kgs
Release date
2020-02-17

78273-80-0, RoxatidineRelated Search:

Acetamide Famotidine Propyl butyrate Thioacetamide 3-Mercaptopropyltriethoxysilane Cimetidine DIACETAMIDE Propyl gallate Acetaminophen 3-Chloropropyltriethoxysilane N,N-Dimethylacetamide 3-Aminopropyltriethoxysilane 3-(1-Piperidinylmethyl)phenol ROXATIDINE OXALATE ROXATIDINE ACETATE ROXATIDINE ACETATE HYDROCHLORIDE,ROXATIDINE ACETATE HCL,ROXATIDINE HCL ACETATE N-[3-[3-(1-Piperidinylmethyl)phenoxy]propyl]amine 2-HYDROXYACETAMIDE

  • ROXATIDINE
  • n-{3-[3-(1-piperidinylmethyl)phenoxy]propyl}hydroxyacetamide
  • 2-Hydroxy-N-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]acetamide
  • 2-Hydroxy-N-[3-[m-(piperidinomethyl)phenoxy]propyl]acetamide
  • ROXATIDINE ENTERPRISE STANDARD
  • RoxatidineAcetateHclBase
  • ROXATIDINE(SUBJECTTOPATENTFREE)
  • desacetyl-TZU-0460
  • 2-hydroxy-N-[3-[3-(piperidinomethyl)phenoxy]propyl] acetamide
  • 2-hydroxy-N-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]acetamide hydrochloride
  • Acetamide, 2-hydroxy-N-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]-
  • Roxatidine USP/EP/BP
  • Benzaldehyde,5-methoxy-7-nitro-
  • Roxatidine in acetonitrile
  • 78273-80-0
  • 8273-80-0
  • C17H26N2O3
  • APIs