Roxatidine

ChemicalBook > CAS DataBase List > Roxatidine

Product Name: Roxatidine
CAS No.: 78273-80-0
Chemical Name: Roxatidine
Synonyms: ROXATIDINE;desacetyl-TZU-0460;Roxatidine USP/EP/BP;RoxatidineAcetateHclBase;Roxatidine in acetonitrile;ROXATIDINE ENTERPRISE STANDARD;ROXATIDINE(SUBJECTTOPATENTFREE);Benzaldehyde,5-methoxy-7-nitro-;n-{3-[3-(1-piperidinylmethyl)phenoxy]propyl}hydroxyacetamide;2-Hydroxy-N-[3-[m-(piperidinomethyl)phenoxy]propyl]acetamide
CBNumber: CB1472068
Molecular Formula: C17H26N2O3
Formula Weight: 306.4
MOL File: 78273-80-0.mol

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Roxatidine Property

Melting point:: 59-60 °C
Boiling point:: 524.3±45.0 °C(Predicted)
Density: 1.137±0.06 g/cm3(Predicted)
storage temp.: -20°
solubility: Soluble in DMSO (up to 25 mg/ml).
pka: 13.34±0.10(Predicted)
form: oil
color: Colorless to pale yellow
Stability:: Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
CAS DataBase Reference: 78273-80-0(CAS DataBase Reference)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: API0005304
Product name: ROXATIDINE
Purity: 95.00%
Packaging: 5MG
Price: $504.65
Updated: 2021/12/16

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Roxatidine Chemical Properties,Usage,Production

Description

Roxatidine (78273-80-0) is a novel histamine H2 receptor antagonist.1?Suppresses inflammatory responses via inhibition of NFκB and p38 MAPK activation in LPS-induced RAW 264.7 macrophages.2?Clinically useful agent for prevention and healing of gastric and duodenal ulcers and bleeding.3?Attenuates degradation of extracellular matrix in osteoarthritis models by inactivating the NFkB pathway.4

Uses

Anti-ulcerative.

References

1) Mills and Wood (1989),?The pharmacology of histamine H2-receptor antagonists; Methods Find. Exp. Clin. Pharmacol., 11 Suppl. 1?87 2) Cho?et al. (2011), Roxatidine suppresses inflammatory responses via inhibition of NF-κB and p38 MAPK activation in LPS-induced RAW 264.7 macrophages; J. Cell. Biochem.,?112?3648 3) Imaeda?et al.?(2011),?Effect of lansoprazole versus roxatidine on prevention of bleeding and promotion of ulcer healing after endoscopic submucosal dissection for superficial gastric neoplasia; J. Gastroenterol.,?46?1267 4) Ze?et al. (2017),?Roxatidine Attenuates Degradation of Extracellular Matrix;?Biomed. Pharmacother.,?95?1156

Roxatidine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Roxatidine manufacturers

Sinoway Industrial co., ltd.

Product: Roxatidine 78273-80-0
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20tons
Release date: 2024-11-29

Shaanxi Dideu Medichem Co. Ltd

Product: Roxatidine 78273-80-0
Price: US $1.00-1.00/Kg/Bag
Min. Order: 1g
Purity: 99%
Supply Ability: 50tons
Release date: 2020-04-30

Hebei Weibang Biotechnology Co., Ltd

Product: Roxatidine 78273-80-0
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-29

78273-80-0, RoxatidineRelated Search:

Acetamide Famotidine Propyl butyrate Thioacetamide 3-Mercaptopropyltriethoxysilane Cimetidine DIACETAMIDE Propyl gallate Acetaminophen 3-Chloropropyltriethoxysilane 3-Aminopropyltriethoxysilane N,N-Dimethylacetamide 3-(1-Piperidinylmethyl)phenol ROXATIDINE OXALATE ROXATIDINE ACETATE ROXATIDINE ACETATE HYDROCHLORIDE,ROXATIDINE ACETATE HCL,ROXATIDINE HCL ACETATE N-[3-[3-(1-Piperidinylmethyl)phenoxy]propyl]amine 2-HYDROXYACETAMIDE

ROXATIDINE

n-{3-[3-(1-piperidinylmethyl)phenoxy]propyl}hydroxyacetamide

2-Hydroxy-N-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]acetamide

2-Hydroxy-N-[3-[m-(piperidinomethyl)phenoxy]propyl]acetamide

ROXATIDINE ENTERPRISE STANDARD

RoxatidineAcetateHclBase

ROXATIDINE(SUBJECTTOPATENTFREE)

desacetyl-TZU-0460

2-hydroxy-N-[3-[3-(piperidinomethyl)phenoxy]propyl] acetamide

2-hydroxy-N-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]acetamide hydrochloride

Acetamide, 2-hydroxy-N-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]-

Roxatidine USP/EP/BP

Benzaldehyde,5-methoxy-7-nitro-

Roxatidine in acetonitrile

78273-80-0

8273-80-0

C17H26N2O3

APIs