Roxatidine

Product Name: Roxatidine
CAS No.: 78273-80-0
Chemical Name: Roxatidine
Synonyms: ROXATIDINE;desacetyl-TZU-0460;Roxatidine USP/EP/BP;RoxatidineAcetateHclBase;Roxatidine in acetonitrile;ROXATIDINE ENTERPRISE STANDARD;ROXATIDINE(SUBJECTTOPATENTFREE);Benzaldehyde,5-methoxy-7-nitro-;n-{3-[3-(1-piperidinylmethyl)phenoxy]propyl}hydroxyacetamide;2-Hydroxy-N-[3-[m-(piperidinomethyl)phenoxy]propyl]acetamide
CBNumber: CB1472068
Molecular Formula: C17H26N2O3
Formula Weight: 306.4
MOL File: 78273-80-0.mol

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Roxatidine Property

Melting point:: 59-60 °C
Boiling point:: 524.3±45.0 °C(Predicted)
Density: 1.137±0.06 g/cm3(Predicted)
storage temp.: -20°
solubility: Soluble in DMSO (up to 25 mg/ml).
pka: 13.34±0.10(Predicted)
form: oil
color: Colorless to pale yellow
Stability:: Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
CAS DataBase Reference: 78273-80-0(CAS DataBase Reference)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: API0005304
Product name: ROXATIDINE
Purity: 95.00%
Packaging: 5MG
Price: $504.65
Updated: 2021/12/16

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Roxatidine Chemical Properties,Usage,Production

Description

Roxatidine (78273-80-0) is a novel histamine H2 receptor antagonist.1?Suppresses inflammatory responses via inhibition of NFκB and p38 MAPK activation in LPS-induced RAW 264.7 macrophages.2?Clinically useful agent for prevention and healing of gastric and duodenal ulcers and bleeding.3?Attenuates degradation of extracellular matrix in osteoarthritis models by inactivating the NFkB pathway.4

Uses

Anti-ulcerative.

References

1) Mills and Wood (1989),?The pharmacology of histamine H2-receptor antagonists; Methods Find. Exp. Clin. Pharmacol., 11 Suppl. 1?87 2) Cho?et al. (2011), Roxatidine suppresses inflammatory responses via inhibition of NF-κB and p38 MAPK activation in LPS-induced RAW 264.7 macrophages; J. Cell. Biochem.,?112?3648 3) Imaeda?et al.?(2011),?Effect of lansoprazole versus roxatidine on prevention of bleeding and promotion of ulcer healing after endoscopic submucosal dissection for superficial gastric neoplasia; J. Gastroenterol.,?46?1267 4) Ze?et al. (2017),?Roxatidine Attenuates Degradation of Extracellular Matrix;?Biomed. Pharmacother.,?95?1156

Roxatidine Preparation Products And Raw materials

Raw materials

Preparation Products

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Roxatidine Suppliers

China 72 Europe 2 Germany 1 India 2 United Kingdom 3 United States 13 Global 93

XiaoGan ShenYuan ChemPharm co,ltd

Tel: 15527768850
Email: 1791901229@qq.com
Country: China
ProdList: 8843
Advantage: 52

BOC Sciences

Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 14055
Advantage: 65

Beijing HuaMeiHuLiBiological Chemical

Tel: 010-56205725
Fax: 010-65763397
Email: waley188@sohu.com
Country: China
ProdList: 12335
Advantage: 58

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 18042
Advantage: 56

Shanghai Kewel Chemical Co., Ltd.

Tel: 021-64609169 18901607656
Fax: 021-64609160
Email: greensnown@163.com
Country: China
ProdList: 9906
Advantage: 50

DebyeTec.com Inc.

Tel: 18086626237 18086626237
Fax: qq:2693528373
Email: sales@debyesci.com
Country: China
ProdList: 2644
Advantage: 56

BOC Sciences

Tel: 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 9923
Advantage: 65

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Wuhan FengyaoTonghui Chemical Products Co., Ltd.

Tel: 027-87466105 15377573527
Email: 2678564200@qq.com
Country: China
ProdList: 17987
Advantage: 58

Nanjing Daqin Pharmaceutical Technology Co., Ltd.

Tel: 025-58470199 18351831988
Fax: 025-58470199
Email: sales@daqinpharma.com
Country: China
ProdList: 312
Advantage: 58

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View Lastest Price from Roxatidine manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: Roxatidine 78273-80-0
Price: US $1.00-1.00/Kg/Bag
Min. Order: 1g
Purity: 99%
Supply Ability: 50tons
Release date: 2020-04-30

Hebei Weibang Biotechnology Co., Ltd

Product: Roxatidine 78273-80-0
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-29

Career Henan Chemical Co

Product: Roxatidine 78273-80-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kgs
Release date: 2020-02-17

78273-80-0, RoxatidineRelated Search:

Acetamide Famotidine Propyl butyrate Thioacetamide 3-Mercaptopropyltriethoxysilane Cimetidine DIACETAMIDE Propyl gallate Acetaminophen 3-Chloropropyltriethoxysilane N,N-Dimethylacetamide 3-Aminopropyltriethoxysilane 3-(1-Piperidinylmethyl)phenol ROXATIDINE OXALATE ROXATIDINE ACETATE ROXATIDINE ACETATE HYDROCHLORIDE,ROXATIDINE ACETATE HCL,ROXATIDINE HCL ACETATE N-[3-[3-(1-Piperidinylmethyl)phenoxy]propyl]amine 2-HYDROXYACETAMIDE

ROXATIDINE

n-{3-[3-(1-piperidinylmethyl)phenoxy]propyl}hydroxyacetamide

2-Hydroxy-N-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]acetamide

2-Hydroxy-N-[3-[m-(piperidinomethyl)phenoxy]propyl]acetamide

ROXATIDINE ENTERPRISE STANDARD

RoxatidineAcetateHclBase

ROXATIDINE(SUBJECTTOPATENTFREE)

desacetyl-TZU-0460

2-hydroxy-N-[3-[3-(piperidinomethyl)phenoxy]propyl] acetamide

2-hydroxy-N-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]acetamide hydrochloride

Acetamide, 2-hydroxy-N-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]-

Roxatidine USP/EP/BP

Benzaldehyde,5-methoxy-7-nitro-

Roxatidine in acetonitrile

78273-80-0

8273-80-0

C17H26N2O3

APIs