1-AMINO-3,6,9-TRIOXAUNDECANYL-11-OL
- Product Name
- 1-AMINO-3,6,9-TRIOXAUNDECANYL-11-OL
- CAS No.
- 86770-74-3
- Chemical Name
- 1-AMINO-3,6,9-TRIOXAUNDECANYL-11-OL
- Synonyms
- 2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethanol;NH2-PEG4;H2N-PEG4-OH;Amino-PEG4-alcohol;t4egma;NH2-PEG4-OH;H2N-dPEG4)-OH;NH2-PEG4-alcohol;Amino-dPEG(R)4-OH;HO-(CH2CH2O)4-NH2
- CBNumber
- CB1472260
- Molecular Formula
- C8H19NO4
- Formula Weight
- 193.24
- MOL File
- 86770-74-3.mol
1-AMINO-3,6,9-TRIOXAUNDECANYL-11-OL Property
- Boiling point:
- 301.6±27.0 °C(Predicted)
- Density
- 1.068±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- pka
- 14.36±0.10(Predicted)
- form
- solid or viscous liquid
- color
- Colourless to Dark Brown
- Appearance
- colorless to yellowish oil
- Water Solubility
- Water: 50 mg/mL (258.75 mM)
- Water Solubility
- Water: 50 mg/mL (258.75 mM)
- InChI
- InChI=1S/C8H19NO4/c9-1-3-11-5-7-13-8-6-12-4-2-10/h10H,1-9H2
- InChIKey
- ANOJXMUSDYSKET-UHFFFAOYSA-N
- SMILES
- C(O)COCCOCCOCCN
- CAS DataBase Reference
- 86770-74-3
- EPA Substance Registry System
- Ethanol, 2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]- (86770-74-3)
Safety
- HS Code
- 2922190090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- QBD10249
- Product name
- Amino-dPEG®4-OH
- Packaging
- 100MG
- Price
- $148
- Updated
- 2025/07/31
- Product number
- QBD10249
- Product name
- Amino-dPEG®4-OH
- Packaging
- 1000MG
- Price
- $296
- Updated
- 2025/07/31
- Product number
- CDS020855
- Product name
- 2-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)ethanol
- Packaging
- 50 mg
- Price
- $42.8
- Updated
- 2025/07/31
- Product number
- A631975
- Product name
- 1-Amino-3,6,9-trioxaundecanyl-11-ol
- Packaging
- 100mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- Z5221
- Product name
- 2-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)ethanol
- Packaging
- 250mg
- Price
- $89
- Updated
- 2021/12/16
1-AMINO-3,6,9-TRIOXAUNDECANYL-11-OL Chemical Properties,Usage,Production
Description
Amino-PEG4-alcohol is a very popular PEG reagent containing an amino group (NH2) with a hydroxyl group (OH). The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.
Chemical Properties
Pale Yellow Oil
Uses
1-Amino-3,6,9-trioxaundecanyl-11-ol can be used in a test kit to detect progesterone.
reaction suitability
reagent type: cross-linking reagent
reactivity: carboxyl reactive
Synthesis
86770-67-4
86770-74-3
General procedure for the synthesis of 1-amino-3,6,9-trioxa-11-undecanol from 11-azido-3,6,9-trioxa-11-undecanol: the azide was mixed with Pd/C catalyst (150 mg) in methanol (7.0 mL) and the reaction was stirred for 12 h under hydrogen atmosphere (1 atm). Upon completion of the reaction, the catalyst was removed by diatomaceous earth filtration and the filtrate was concentrated to afford the target product 1-amino-3,6,9-trioxa-11-undecanol in quantitative yield (0.520 g, 2.7 mmol). Ref: Xie, H. Z.; Braha, O.; Gu, L. Q.; Cheley, S.; Bayley, H. Chem. Biol. 2005, 12, 109-120.
IC 50
PEGs; Non-cleavable Linker
References
[1] Helvetica Chimica Acta, 1991, vol. 74, # 8, p. 1697 - 1706
[2] Organic Letters, 2009, vol. 11, # 1, p. 193 - 196
[3] Angewandte Chemie - International Edition, 2015, vol. 54, # 35, p. 10327 - 10330
[4] Angew. Chem., 2015, vol. 35, # 37, p. 10467 - 10471,5
[5] Chemistry - A European Journal, 2018, vol. 24, # 4, p. 813 - 817
1-AMINO-3,6,9-TRIOXAUNDECANYL-11-OL Preparation Products And Raw materials
Raw materials
Preparation Products
1-AMINO-3,6,9-TRIOXAUNDECANYL-11-OL Suppliers
- Tel
- --
- Fax
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- sales@apolloscientific.co.uk
- Country
- United Kingdom
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View Lastest Price from 1-AMINO-3,6,9-TRIOXAUNDECANYL-11-OL manufacturers
- Product
- NH2-PEG4-OH 86770-74-3
- Price
- US $1792.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 300kg
- Release date
- 2025-11-20
- Product
- 2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethanol 86770-74-3
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 1g/bottle, 10g/bottle, 100g/bottle
- Release date
- 2025-09-11
- Product
- Amino-PEG4-alcohol 86770-74-3
- Price
- US $2.00-6.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2025-08-05