ChemicalBook > CAS DataBase List > ANGIOTENSIN I/II (1-6)

ANGIOTENSIN I/II (1-6)

Product Name: ANGIOTENSIN I/II (1-6)
CAS No.: 47896-63-9
Chemical Name: ANGIOTENSIN I/II (1-6)
Synonyms: DRVYIH;H2N-DRVYIH-OH;ANGIOTENSIN 1/2 (1-6);ANGIOTENSIN I/II (1-6);ASP-ARG-VAL-TYR-ILE-HIS;H-ASP-ARG-VAL-TYR-ILE-HIS-OH;1-6-Angiotensin II, 5-L-isoleucine-;Angiotensin I/II (1-6) H-Asp-Arg-Val-Tyr-Ile-His-OH;Angiotensin I/II (16),Angiotensin I/II (1-6),Inhibitor,inhibit,Angiotensin I/II (1 6),Angiotensin Receptor
CBNumber: CB1473454
Molecular Formula: C36H55N11O10
Formula Weight: 801.89
MOL File: 47896-63-9.mol

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ANGIOTENSIN I/II (1-6) Property

storage temp.: -15°C
solubility: insoluble in EtOH; ≥62.4 mg/mL in H2O; ≥80.2 mg/mL in DMSO
form: solid

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ApexBio Technology

Product number: A1048
Product name: Angiotensin1/2(1-6)
Packaging: 5mg
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Updated: 2021/12/16

ApexBio Technology

Product number: A1048
Product name: Angiotensin1/2(1-6)
Packaging: 10mg
Price: $100
Updated: 2021/12/16

ApexBio Technology

Product number: A1048
Product name: Angiotensin1/2(1-6)
Packaging: 25mg
Price: $140
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA108793
Product name: Angiotensin I/II (1-6) H-Asp-Arg-Val-Tyr-Ile-His-OH
Packaging: 10mg
Price: $153
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA108793
Product name: Angiotensin I/II (1-6) H-Asp-Arg-Val-Tyr-Ile-His-OH
Packaging: 25mg
Price: $305
Updated: 2021/12/16

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ANGIOTENSIN I/II (1-6) Chemical Properties,Usage,Production

Uses

Angiotensin I/II 1-6 contains the amino acids 1-6 and is converted from Angiotensin I/II peptide. The precursor angiotensinogen is cleaved by renin to form angiotensin I. Angiotensin I ishydrolyzed by angiotensin-converting enzyme (ACE) to form the biologically active angiotensin II. Angiotensin II has been investigated for the treatment, basic science, and diagnostic of Hypertension, Renin Angiotensin System, and Idiopathic Membranous Nephropathy[1][2][3].

Biological Activity

angiotensin i/ii (1-6) is a peptide (asp-arg-val-tyr-ile-his) that contains the amino acids 1-6 and is converted from angiotensin i/ii peptide.angiotensin i is formed by the action of renin on angiotensinogen, an α-2-globulin with 12 amino acids. angiotensinogen is produced constitutively and released into the circulation mainly by the liver. renin cleaves the peptide bond between the leucine (leu) and valine (val) residues on angiotensinogen, creating the ten-amino acid peptide angiotensin i. angiotensin i is converted to angiotensin ii (aii) through removal of two c-terminal residues by angiotensin-converting enzyme (ace), primarily by ace within the lung.angiotensin is a peptide hormone that causes vasoconstriction and a subsequent increase in blood pressure. angiotensin also stimulates the release of aldosterone, which promotes sodium retention in the distal nephron, thereby increasing blood pressure.figure1 formula of angiotensin i/ii (1-6)

References

1. Basso N, Terragno NA (December 2001). "History about the discovery of the renin-angiotensin system". Hypertension 38 (6): 1246–9. 2. Richard A. Preston. et. (1998). “Age-Race Subgroup Compared With Renin Profile as Predictors of Blood Pressure Response to Antihypertensive Therapy”. JAMA. 1998;280(13):1168-1172.3. Williams GH, Dluhy RG (2008). "Chapter 336: Disorders of the Adrenal Cortex". In Loscalzo J, Fauci AS, Braunwald E, Kasper DL, Hauser SL, Longo DL. Harrison's principles of internal medicine. McGraw-Hill Medical.

ANGIOTENSIN I/II (1-6) Preparation Products And Raw materials

Raw materials

Preparation Products

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47896-63-9, ANGIOTENSIN I/II (1-6)Related Search:

ANGIOTENSIN III, HUMAN (SAR1,ILE4,8)-ANGIOTENSIN II ANGIOTENSINOGEN (1-13) (HUMAN) H-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-OH BRADYKININ (1-6) Angiogenin (108-122) TFA ANGIOTENSIN I/II (1-5) ABZ-GLY-4-NITRO-PHE-PRO-OH ANGIOTENSIN I/II (3-7) (DES-ASP1,ILE8)-ANGIOTENSIN II ASP-ARG-VAL-TYR Angiotensin acetate H-MET-LYS-ARG-SER-ARG-GLY-PRO-SER-PRO-ARG-ARG-OH ANGIOTENSIN I/II (4-8) ANGIOTENSIN II, HUMAN ANGIOTENSIN 1/2 + A (2 - 8) N-BENZOYL-PHE-ALA-PRO SAR-ARG-VAL-TYR-ILE-HIS-PRO-PHE

Angiotensin I/II (1-6) H-Asp-Arg-Val-Tyr-Ile-His-OH

ANGIOTENSIN I/II (1-6)

ANGIOTENSIN 1/2 (1-6)

H2N-DRVYIH-OH

H-ASP-ARG-VAL-TYR-ILE-HIS-OH

ASP-ARG-VAL-TYR-ILE-HIS

1-6-Angiotensin II, 5-L-isoleucine-

Angiotensin I/II (16),Angiotensin I/II (1-6),Inhibitor,inhibit,Angiotensin I/II (1 6),Angiotensin Receptor

DRVYIH

47896-63-9

C36H55N11O10

Cardiovascular