ChemicalBook > CAS DataBase List > (S)-4-Hydroxy-2-pyrrolidinone

(S)-4-Hydroxy-2-pyrrolidinone

Product Name
(S)-4-Hydroxy-2-pyrrolidinone
CAS No.
68108-18-9
Chemical Name
(S)-4-Hydroxy-2-pyrrolidinone
Synonyms
SHPD;OxiracetaM iMpurity A;Oxiracetam Impurity 9;Oxiracetam impurity H;Oxiracetam Impurity N;Busulfan Impurity1706;Oxiracetam impurities1718;4-HYDROXY-PYRROLIDIN-2-ONE;(S)-4-HYDROXY-2-PYRROLIDONE;(s)-β-hydroxy-γ-butyrolactam
CBNumber
CB1474345
Molecular Formula
C4H7NO2
Formula Weight
101.1
MOL File
68108-18-9.mol
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(S)-4-Hydroxy-2-pyrrolidinone Property

Melting point:
156-159 °C (lit.)
alpha 
-41 º (c=% in ethanol)
Boiling point:
363.6±35.0 °C(Predicted)
Density 
1.292±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
Water Solubility 
Slightly soluble in water
pka
13.62±0.20(Predicted)
form 
Solid
color 
White to off-white
optical activity
[α]23/D 43°, c = 1 in ethanol
BRN 
1524192
InChIKey
IOGISYQVOGVIEU-VKHMYHEASA-N
CAS DataBase Reference
68108-18-9(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn
Risk Statements 
22-41
Safety Statements 
22-24/25-36-26
WGK Germany 
3
HS Code 
29349990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
479179
Product name
(S)-(?)-4-Hydroxy-2-pyrrolidinone
Purity
97%
Packaging
5g
Price
$94
Updated
2024/03/01
Sigma-Aldrich
Product number
479179
Product name
(S)-(?)-4-Hydroxy-2-pyrrolidinone
Purity
97%
Packaging
1g
Price
$52.5
Updated
2023/06/20
TCI Chemical
Product number
H1368
Product name
(S)-(-)-4-Hydroxy-2-pyrrolidone
Purity
>98.0%(GC)
Packaging
1g
Price
$205
Updated
2024/03/01
Alfa Aesar
Product number
H66455
Product name
(S)-(-)-4-Hydroxy-2-pyrrolidinone, 97+%
Packaging
250mg
Price
$36.7
Updated
2023/06/20
Alfa Aesar
Product number
H66455
Product name
(S)-(-)-4-Hydroxy-2-pyrrolidinone, 97+%
Packaging
1g
Price
$106
Updated
2023/06/20
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(S)-4-Hydroxy-2-pyrrolidinone Chemical Properties,Usage,Production

Chemical Properties

White crystal

Uses

(S)-(?)-4-Hydroxy-2-pyrrolidinone can be used as a starting material in the preparation of:

  • Biologically significant pyrrolo[1,2:1′,2′]azepino[5,6-b]indole derivatives.
  • Substituted azepanes by reacting with various aldehydes via photochemical [5+2] cycloaddition.

Uses

The (S)-enantiomer intermediate in the preparation of Oxiracetam

General Description

4-Hydroxy-2-pyrrolidinone is an important building block found in many bioactive compounds like streptopyrrolidine. It can be used as an intermediate in the synthesis of various γ-amino acids (GABA) and substituted 2-pyrrolidinones like cynometrine and cynodine.

(S)-4-Hydroxy-2-pyrrolidinone Preparation Products And Raw materials

Raw materials

Preparation Products

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(S)-4-Hydroxy-2-pyrrolidinone Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
Advantage
66
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12390
Advantage
60
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
Advantage
62
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14103
Advantage
59
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View Lastest Price from (S)-4-Hydroxy-2-pyrrolidinone manufacturers

R&D Scientific Inc.
Product
4-Hydroxy-2-pyrrolidone 68108-18-9
Price
US $2800.00/Kg
Min. Order
1Kg
Purity
98
Supply Ability
500 Kg
Release date
2024-05-08
Zhuozhou Wenxi import and Export Co., Ltd
Product
(S)-4-Hydroxy-2-pyrrolidinone 68108-18-9
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27
Career Henan Chemical Co
Product
(S)-4-Hydroxy-2-pyrrolidinone 68108-18-9
Price
US $1.00/kg
Min. Order
1kg
Purity
95%-99%
Supply Ability
as request
Release date
2018-12-24

68108-18-9, (S)-4-Hydroxy-2-pyrrolidinoneRelated Search:


  • 2-PYRROLIDINONE, 4-HYDROXY-, (S)
  • 2-PYRROLIDINONE, 4-HYDROXY-, (4S)-
  • (4S)-4-HYDROXYPYRROLIDIN-2-ONE
  • 4-HYDROXY-PYRROLIDIN-2-ONE
  • (s)-(-)-β-hydroxy-γ-butyrolactam
  • (s)-β-hydroxy-γ-butyrolactam
  • (S)-(-)-4-HYDROXY-2-PYRROLIDINONE
  • (S)-(+)-4-HYDROXY-2-PYRROLIDINONE
  • (S)-4-HYDROXY-2-PYRROLIDINONE
  • (S)-4-HYDROXY-2-PYRROLIDONE
  • (S)-4-HYDROXY-PYRROLIDINE-2-ONE
  • SHPD
  • (S)-BETA-HYDROXY-GAMMA-BUTYROLACTAM
  • (S)-(-)-4-Hydroxy-2-pyrrolinone
  • (4S)-4-hydroxy-2-pyrrolidone
  • (S)-4-Hydroxy-pyrrolidin-2-one
  • (4S)-(-)-4-Hydroxy-2-oxopyrrolidine, (4S)-(-)-beta-Hydroxy-gamma-butyrolactam
  • (4S)-4-Hydroxy-2-pyrrolidinone
  • OxiracetaM iMpurity A
  • Oxiracetam Impurity 9
  • (S)-4-Mercapto-2-pyrrolidone
  • Oxiracetam Impurity A ((S)-4-Hydroxy-2-pyrrolidinone)
  • (S)-(-)-4-Hydroxy-2-pyrrolidinone 97%
  • (S)-4-Hydroxy-2-pyrrolidone,99%e.e.
  • Oxiracetam impurity H
  • Oxiracetam Impurity N
  • (S)-(-)-4-Hydroxy-2-pyrrolidone&gt
  • Busulfan Impurity1706
  • Oxiracetam impurities1718
  • (S)-(-)-4-Hydroxy-2-pyrrolidinone (Oxiracetam Impurity)
  • 68108-18-9
  • C4H7NO2
  • Heterocyclic Building Blocks
  • Pyrrolidines
  • Chiral Building Blocks
  • Asymmetric Synthesis
  • Amines
  • Chiral Reagents
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Chiral
  • Pyrrolidinone derivatives
  • Drug Intermediates